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Similar articles for PubMed (Select 23722650)


Staurosporine is chemoprotective by inducing G1 arrest in a Chk1- and pRb-dependent manner.

Murray MM, Bui T, Smith M, Bagheri-Yarmand R, Wingate H, Hunt KK, Keyomarsi K.

Carcinogenesis. 2013 Oct;34(10):2244-52. doi: 10.1093/carcin/bgt186. Epub 2013 May 30.


Deficiency of G1 regulators P53, P21Cip1 and/or pRb decreases hepatocyte sensitivity to TGFbeta cell cycle arrest.

Sheahan S, Bellamy CO, Dunbar DR, Harrison DJ, Prost S.

BMC Cancer. 2007 Nov 19;7:215.


CDK4 inhibition restores G(1)-S arrest in MYCN-amplified neuroblastoma cells in the context of doxorubicin-induced DNA damage.

Gogolin S, Ehemann V, Becker G, Brueckner LM, Dreidax D, Bannert S, Nolte I, Savelyeva L, Bell E, Westermann F.

Cell Cycle. 2013 Apr 1;12(7):1091-104. doi: 10.4161/cc.24091. Epub 2013 Mar 5.


The specific role of pRb in p16 (INK4A) -mediated arrest of normal and malignant human breast cells.

Bazarov AV, Lee WJ, Bazarov I, Bosire M, Hines WC, Stankovich B, Chicas A, Lowe SW, Yaswen P.

Cell Cycle. 2012 Mar 1;11(5):1008-13. doi: 10.4161/cc.11.5.19492. Epub 2012 Mar 1.


Staurosporine-induced G(1) arrest in cancer cells depends on an intact pRB but is independent of p16 status.

Zhou W, Lin Y, Wersto R, Chrest J, Gabrielson E.

Cancer Lett. 2002 Sep 8;183(1):103-7.


Piperine causes G1 phase cell cycle arrest and apoptosis in melanoma cells through checkpoint kinase-1 activation.

Fofaria NM, Kim SH, Srivastava SK.

PLoS One. 2014 May 7;9(5):e94298. doi: 10.1371/journal.pone.0094298. eCollection 2014.


PTEN tumour suppressor is linked to the cell cycle control through the retinoblastoma protein.

Paramio JM, Navarro M, Segrelles C, Gómez-Casero E, Jorcano JL.

Oncogene. 1999 Dec 9;18(52):7462-8.


Differing effects of staurosporine and UCN-01 on RB protein phosphorylation and expression of lung cancer cell lines.

Shimizu E, Zhao MR, Nakanishi H, Yamamoto A, Yoshida S, Takada M, Ogura T, Sone S.

Oncology. 1996 Nov-Dec;53(6):494-504.


Inhibition of Hsp90 function by ansamycins causes retinoblastoma gene product-dependent G1 arrest.

Srethapakdi M, Liu F, Tavorath R, Rosen N.

Cancer Res. 2000 Jul 15;60(14):3940-6.


Effects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplication.

Niculescu AB 3rd, Chen X, Smeets M, Hengst L, Prives C, Reed SI.

Mol Cell Biol. 1998 Jan;18(1):629-43. Erratum in: Mol Cell Biol 1998 Mar;18(3):1763.


p53-dependent G1 arrest involves pRB-related proteins and is disrupted by the human papillomavirus 16 E7 oncoprotein.

Slebos RJ, Lee MH, Plunkett BS, Kessis TD, Williams BO, Jacks T, Hedrick L, Kastan MB, Cho KR.

Proc Natl Acad Sci U S A. 1994 Jun 7;91(12):5320-4.


Protection of normal proliferating cells against chemotherapy by staurosporine-mediated, selective, and reversible G(1) arrest.

Chen X, Lowe M, Herliczek T, Hall MJ, Danes C, Lawrence DA, Keyomarsi K.

J Natl Cancer Inst. 2000 Dec 20;92(24):1999-2008.


Baicalein induces G1 arrest in oral cancer cells by enhancing the degradation of cyclin D1 and activating AhR to decrease Rb phosphorylation.

Cheng YH, Li LA, Lin P, Cheng LC, Hung CH, Chang NW, Lin C.

Toxicol Appl Pharmacol. 2012 Sep 15;263(3):360-7. doi: 10.1016/j.taap.2012.07.010. Epub 2012 Jul 20.

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