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Results: 1 to 20 of 110

1.

RRM2 regulates Bcl-2 in head and neck and lung cancers: a potential target for cancer therapy.

Rahman MA, Amin AR, Wang D, Koenig L, Nannapaneni S, Chen Z, Wang Z, Sica G, Deng X, Chen ZG, Shin DM.

Clin Cancer Res. 2013 Jul 1;19(13):3416-28. doi: 10.1158/1078-0432.CCR-13-0073. Epub 2013 May 29.

PMID:
23719266
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

TNF-α promotes c-REL/ΔNp63α interaction and TAp73 dissociation from key genes that mediate growth arrest and apoptosis in head and neck cancer.

Lu H, Yang X, Duggal P, Allen CT, Yan B, Cohen J, Nottingham L, Romano RA, Sinha S, King KE, Weinberg WC, Chen Z, Van Waes C.

Cancer Res. 2011 Nov 1;71(21):6867-77. doi: 10.1158/0008-5472.CAN-11-2460. Epub 2011 Sep 20.

PMID:
21933882
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Systemic delivery of siRNA nanoparticles targeting RRM2 suppresses head and neck tumor growth.

Rahman MA, Amin AR, Wang X, Zuckerman JE, Choi CH, Zhou B, Wang D, Nannapaneni S, Koenig L, Chen Z, Chen ZG, Yen Y, Davis ME, Shin DM.

J Control Release. 2012 May 10;159(3):384-92. doi: 10.1016/j.jconrel.2012.01.045. Epub 2012 Feb 8.

PMID:
22342644
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Essential role of caspase-8 in p53/p73-dependent apoptosis induced by etoposide in head and neck carcinoma cells.

Liu J, Uematsu H, Tsuchida N, Ikeda MA.

Mol Cancer. 2011 Jul 31;10:95. doi: 10.1186/1476-4598-10-95.

PMID:
21801448
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

The proteasome inhibitor MG132 potentiates TRAIL receptor agonist-induced apoptosis by stabilizing tBid and Bik in human head and neck squamous cell carcinoma cells.

Sung ES, Park KJ, Choi HJ, Kim CH, Kim YS.

Exp Cell Res. 2012 Aug 1;318(13):1564-76. doi: 10.1016/j.yexcr.2012.04.003. Epub 2012 Apr 10.

PMID:
22513214
[PubMed - indexed for MEDLINE]
6.

p53 apoptotic response to DNA damage dependent on bcl2 but not bax in head and neck squamous cell carcinoma lines.

Crowe DL, Sinha UK.

Head Neck. 2006 Jan;28(1):15-23.

PMID:
16302195
[PubMed - indexed for MEDLINE]
7.

A signal network involving coactivated NF-kappaB and STAT3 and altered p53 modulates BAX/BCL-XL expression and promotes cell survival of head and neck squamous cell carcinomas.

Lee TL, Yeh J, Friedman J, Yan B, Yang X, Yeh NT, Van Waes C, Chen Z.

Int J Cancer. 2008 May 1;122(9):1987-98. doi: 10.1002/ijc.23324.

PMID:
18172861
[PubMed - indexed for MEDLINE]
8.

Novel anti-tumor mechanism of galanin receptor type 2 in head and neck squamous cell carcinoma cells.

Uehara T, Kanazawa T, Mizukami H, Uchibori R, Tsukahara T, Urabe M, Kume A, Misawa K, Carey TE, Suzuki M, Ichimura K, Ozawa K.

Cancer Sci. 2014 Jan;105(1):72-80. doi: 10.1111/cas.12315. Epub 2013 Dec 1.

PMID:
24168112
[PubMed - indexed for MEDLINE]
9.

Targeting antiapoptotic Bcl-2 family members with cell-permeable BH3 peptides induces apoptosis signaling and death in head and neck squamous cell carcinoma cells.

Li R, Boehm AL, Miranda MB, Shangary S, Grandis JR, Johnson DE.

Neoplasia. 2007 Oct;9(10):801-11.

PMID:
17971900
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

CTIP2 expression in human head and neck squamous cell carcinoma is linked to poorly differentiated tumor status.

Ganguli-Indra G, Wasylyk C, Liang X, Millon R, Leid M, Wasylyk B, Abecassis J, Indra AK.

PLoS One. 2009;4(4):e5367. doi: 10.1371/journal.pone.0005367. Epub 2009 Apr 28. Erratum in: PLoS One. 2009;4(4). doi: 10.1371/annotation/b01c646f-14c7-4aac-8812-9ed4f847c857. Indra, Arup [corrected to Indra, Arup K].

PMID:
19399189
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Expression of apoptosis-related genes in human head and neck squamous cell carcinomas undergoing p53-mediated programmed cell death.

Frederick MJ, Holton PR, Hudson M, Wang M, Clayman GL.

Clin Cancer Res. 1999 Feb;5(2):361-9.

PMID:
10037186
[PubMed - indexed for MEDLINE]
Free Article
12.

Spontaneous apoptosis and the expression of p53 and Bcl-2 family proteins in locally advanced head and neck cancer.

Hotz MA, Bosq J, Zbaeren P, Reed J, Schwab G, Krajewski S, Brousset P, Borner MM.

Arch Otolaryngol Head Neck Surg. 1999 Apr;125(4):417-22.

PMID:
10208679
[PubMed - indexed for MEDLINE]
13.

HOXC6 is deregulated in human head and neck squamous cell carcinoma and modulates Bcl-2 expression.

Moon SM, Kim SA, Yoon JH, Ahn SG.

J Biol Chem. 2012 Oct 12;287(42):35678-88. doi: 10.1074/jbc.M112.361675. Epub 2012 Aug 15.

PMID:
22896703
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Degradation of epidermal growth factor receptor mediates dasatinib-induced apoptosis in head and neck squamous cell carcinoma cells.

Lin YC, Wu MH, Wei TT, Chuang SH, Chen KF, Cheng AL, Chen CC.

Neoplasia. 2012 Jun;14(6):463-75.

PMID:
22787428
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Mutation of p53 in head and neck squamous cell carcinoma correlates with Bcl-2 expression and increased susceptibility to cisplatin-induced apoptosis.

Andrews GA, Xi S, Pomerantz RG, Lin CJ, Gooding WE, Wentzel AL, Wu L, Sidransky D, Grandis JR.

Head Neck. 2004 Oct;26(10):870-7.

PMID:
15390206
[PubMed - indexed for MEDLINE]
16.

CK2 modulation of NF-kappaB, TP53, and the malignant phenotype in head and neck cancer by anti-CK2 oligonucleotides in vitro or in vivo via sub-50-nm nanocapsules.

Brown MS, Diallo OT, Hu M, Ehsanian R, Yang X, Arun P, Lu H, Korman V, Unger G, Ahmed K, Van Waes C, Chen Z.

Clin Cancer Res. 2010 Apr 15;16(8):2295-307. doi: 10.1158/1078-0432.CCR-09-3200. Epub 2010 Apr 6.

PMID:
20371694
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Tumor BRCA1, RRM1 and RRM2 mRNA expression levels and clinical response to first-line gemcitabine plus docetaxel in non-small-cell lung cancer patients.

Boukovinas I, Papadaki C, Mendez P, Taron M, Mavroudis D, Koutsopoulos A, Sanchez-Ronco M, Sanchez JJ, Trypaki M, Staphopoulos E, Georgoulias V, Rosell R, Souglakos J.

PLoS One. 2008;3(11):e3695. doi: 10.1371/journal.pone.0003695. Epub 2008 Nov 11.

PMID:
19002265
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Knockdown of the Bcl-2 gene increases sensitivity to EGFR tyrosine kinase inhibitors in the H1975 lung cancer cell line harboring T790M mutation.

Zou M, Xia S, Zhuang L, Han N, Chu Q, Chao T, Peng P, Chen Y, Gui Q, Yu S.

Int J Oncol. 2013 Jun;42(6):2094-102. doi: 10.3892/ijo.2013.1895. Epub 2013 Apr 12.

PMID:
23588221
[PubMed - indexed for MEDLINE]
19.

Insulin-like growth factor-I receptor signaling pathway induces resistance to the apoptotic activities of SCH66336 (lonafarnib) through Akt/mammalian target of rapamycin-mediated increases in survivin expression.

Oh SH, Jin Q, Kim ES, Khuri FR, Lee HY.

Clin Cancer Res. 2008 Mar 1;14(5):1581-9. doi: 10.1158/1078-0432.CCR-07-0952.

PMID:
18316583
[PubMed - indexed for MEDLINE]
Free Article
20.

TrkB induces EMT and has a key role in invasion of head and neck squamous cell carcinoma.

Kupferman ME, Jiffar T, El-Naggar A, Yilmaz T, Zhou G, Xie T, Feng L, Wang J, Holsinger FC, Yu D, Myers JN.

Oncogene. 2010 Apr 8;29(14):2047-59. doi: 10.1038/onc.2009.486. Epub 2010 Jan 18.

PMID:
20101235
[PubMed - indexed for MEDLINE]
Free PMC Article

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