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Items: 1 to 20 of 111

1.

Mitochondrial calcium uniporter, MiRNA and cancer: Live and let die.

Marchi S, Pinton P.

Commun Integr Biol. 2013 May 1;6(3):e23818. doi: 10.4161/cib.23818. Epub 2013 May 13.

2.

MCUR1 is an essential component of mitochondrial Ca2+ uptake that regulates cellular metabolism.

Mallilankaraman K, Cárdenas C, Doonan PJ, Chandramoorthy HC, Irrinki KM, Golenár T, Csordás G, Madireddi P, Yang J, Müller M, Miller R, Kolesar JE, Molgó J, Kaufman B, Hajnóczky G, Foskett JK, Madesh M.

Nat Cell Biol. 2012 Dec;14(12):1336-43. doi: 10.1038/ncb2622. Epub 2012 Nov 25. Erratum in: Nat Cell Biol. 2015 Jul;17(7):953. Nat Cell Biol. 2013 Jan;15(1):123.

3.

Downregulation of the mitochondrial calcium uniporter by cancer-related miR-25.

Marchi S, Lupini L, Patergnani S, Rimessi A, Missiroli S, Bonora M, Bononi A, Corrà F, Giorgi C, De Marchi E, Poletti F, Gafà R, Lanza G, Negrini M, Rizzuto R, Pinton P.

Curr Biol. 2013 Jan 7;23(1):58-63. doi: 10.1016/j.cub.2012.11.026. Epub 2012 Dec 13.

4.

Mitochondrial calcium uniporter activity is dispensable for MDA-MB-231 breast carcinoma cell survival.

Hall DD, Wu Y, Domann FE, Spitz DR, Anderson ME.

PLoS One. 2014 May 6;9(5):e96866. doi: 10.1371/journal.pone.0096866. eCollection 2014.

5.

Impaired expression of the mitochondrial calcium uniporter suppresses mast cell degranulation.

Furuno T, Shinkai N, Inoh Y, Nakanishi M.

Mol Cell Biochem. 2015 Dec;410(1-2):215-21. doi: 10.1007/s11010-015-2554-4. Epub 2015 Sep 8.

PMID:
26350567
6.

MICU1 and MICU2 finely tune the mitochondrial Ca2+ uniporter by exerting opposite effects on MCU activity.

Patron M, Checchetto V, Raffaello A, Teardo E, Vecellio Reane D, Mantoan M, Granatiero V, Szabò I, De Stefani D, Rizzuto R.

Mol Cell. 2014 Mar 6;53(5):726-37. doi: 10.1016/j.molcel.2014.01.013. Epub 2014 Feb 20.

7.

A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter.

De Stefani D, Raffaello A, Teardo E, Szabò I, Rizzuto R.

Nature. 2011 Jun 19;476(7360):336-40. doi: 10.1038/nature10230.

8.

MICU1 motifs define mitochondrial calcium uniporter binding and activity.

Hoffman NE, Chandramoorthy HC, Shamugapriya S, Zhang X, Rajan S, Mallilankaraman K, Gandhirajan RK, Vagnozzi RJ, Ferrer LM, Sreekrishnanilayam K, Natarajaseenivasan K, Vallem S, Force T, Choi ET, Cheung JY, Madesh M.

Cell Rep. 2013 Dec 26;5(6):1576-88. doi: 10.1016/j.celrep.2013.11.026. Epub 2013 Dec 12.

9.

MICU1 is an essential gatekeeper for MCU-mediated mitochondrial Ca(2+) uptake that regulates cell survival.

Mallilankaraman K, Doonan P, Cárdenas C, Chandramoorthy HC, Müller M, Miller R, Hoffman NE, Gandhirajan RK, Molgó J, Birnbaum MJ, Rothberg BS, Mak DO, Foskett JK, Madesh M.

Cell. 2012 Oct 26;151(3):630-44. doi: 10.1016/j.cell.2012.10.011.

10.

MCU encodes the pore conducting mitochondrial calcium currents.

Chaudhuri D, Sancak Y, Mootha VK, Clapham DE.

Elife. 2013 Jun 4;2:e00704. doi: 10.7554/eLife.00704.

11.

The plasma membrane Na+/Ca2+ exchange inhibitor KB-R7943 is also a potent inhibitor of the mitochondrial Ca2+ uniporter.

Santo-Domingo J, Vay L, Hernández-Sanmiguel E, Lobatón CD, Moreno A, Montero M, Alvarez J.

Br J Pharmacol. 2007 Jul;151(5):647-54. Epub 2007 Apr 30.

12.

The mitochondrial Ca(2+) uniporter complex.

Foskett JK, Philipson B.

J Mol Cell Cardiol. 2015 Jan;78:3-8. doi: 10.1016/j.yjmcc.2014.11.015. Epub 2014 Nov 22. Review.

13.

Rearrangement of MICU1 multimers for activation of MCU is solely controlled by cytosolic Ca(2.).

Waldeck-Weiermair M, Malli R, Parichatikanond W, Gottschalk B, Madreiter-Sokolowski CT, Klec C, Rost R, Graier WF.

Sci Rep. 2015 Oct 22;5:15602. doi: 10.1038/srep15602.

14.

Structure and function of the N-terminal domain of the human mitochondrial calcium uniporter.

Lee Y, Min CK, Kim TG, Song HK, Lim Y, Kim D, Shin K, Kang M, Kang JY, Youn HS, Lee JG, An JY, Park KR, Lim JJ, Kim JH, Kim JH, Park ZY, Kim YS, Wang J, Kim do H, Eom SH.

EMBO Rep. 2015 Oct;16(10):1318-33. doi: 10.15252/embr.201540436. Epub 2015 Sep 3.

15.

Distinctive characteristics and functions of multiple mitochondrial Ca2+ influx mechanisms.

Pan S, Ryu SY, Sheu SS.

Sci China Life Sci. 2011 Aug;54(8):763-9. doi: 10.1007/s11427-011-4203-9. Epub 2011 Jul 24. Review.

16.

UCP2 modulates single-channel properties of a MCU-dependent Ca(2+) inward current in mitochondria.

Bondarenko AI, Parichatikanond W, Madreiter CT, Rost R, Waldeck-Weiermair M, Malli R, Graier WF.

Pflugers Arch. 2015 Dec;467(12):2509-18. doi: 10.1007/s00424-015-1727-z. Epub 2015 Aug 16.

17.

Structural and mechanistic insights into MICU1 regulation of mitochondrial calcium uptake.

Wang L, Yang X, Li S, Wang Z, Liu Y, Feng J, Zhu Y, Shen Y.

EMBO J. 2014 Mar 18;33(6):594-604. doi: 10.1002/embj.201386523. Epub 2014 Feb 10.

18.

Gene expression changes of single skeletal muscle fibers in response to modulation of the mitochondrial calcium uniporter (MCU).

Chemello F, Mammucari C, Gherardi G, Rizzuto R, Lanfranchi G, Cagnin S.

Genom Data. 2015 May 30;5:64-7. doi: 10.1016/j.gdata.2015.05.023. eCollection 2015 Sep.

19.

Mitochondrial calcium uniporter Mcu controls excitotoxicity and is transcriptionally repressed by neuroprotective nuclear calcium signals.

Qiu J, Tan YW, Hagenston AM, Martel MA, Kneisel N, Skehel PA, Wyllie DJ, Bading H, Hardingham GE.

Nat Commun. 2013;4:2034. doi: 10.1038/ncomms3034.

20.

Structure and function of the mitochondrial calcium uniporter complex.

De Stefani D, Patron M, Rizzuto R.

Biochim Biophys Acta. 2015 Sep;1853(9):2006-11. doi: 10.1016/j.bbamcr.2015.04.008. Epub 2015 Apr 18. Review.

PMID:
25896525
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