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Results: 1 to 20 of 196

1.

NLRP3 activation induces ASC-dependent programmed necrotic cell death, which leads to neutrophilic inflammation.

Satoh T, Kambe N, Matsue H.

Cell Death Dis. 2013 May 23;4:e644. doi: 10.1038/cddis.2013.169.

PMID:
23703389
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Caspase-1 protein induces apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC)-mediated necrosis independently of its catalytic activity.

Motani K, Kushiyama H, Imamura R, Kinoshita T, Nishiuchi T, Suda T.

J Biol Chem. 2011 Sep 30;286(39):33963-72. doi: 10.1074/jbc.M111.286823. Epub 2011 Aug 8.

PMID:
21832064
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Serum amyloid A activates the NLRP3 inflammasome via P2X7 receptor and a cathepsin B-sensitive pathway.

Niemi K, Teirilä L, Lappalainen J, Rajamäki K, Baumann MH, Öörni K, Wolff H, Kovanen PT, Matikainen S, Eklund KK.

J Immunol. 2011 Jun 1;186(11):6119-28. doi: 10.4049/jimmunol.1002843. Epub 2011 Apr 20.

PMID:
21508263
[PubMed - indexed for MEDLINE]
Free Article
4.

The purinergic 2X7 receptor participates in renal inflammation and injury induced by high-fat diet: possible role of NLRP3 inflammasome activation.

Solini A, Menini S, Rossi C, Ricci C, Santini E, Blasetti Fantauzzi C, Iacobini C, Pugliese G.

J Pathol. 2013 Nov;231(3):342-53. doi: 10.1002/path.4237. Epub 2013 Sep 3.

PMID:
23843215
[PubMed - indexed for MEDLINE]
5.

TLR9 and the NLRP3 inflammasome link acinar cell death with inflammation in acute pancreatitis.

Hoque R, Sohail M, Malik A, Sarwar S, Luo Y, Shah A, Barrat F, Flavell R, Gorelick F, Husain S, Mehal W.

Gastroenterology. 2011 Jul;141(1):358-69. doi: 10.1053/j.gastro.2011.03.041. Epub 2011 Mar 24.

PMID:
21439959
[PubMed - indexed for MEDLINE]
Free PMC Article
6.
7.

Tripartite-motif protein 30 negatively regulates NLRP3 inflammasome activation by modulating reactive oxygen species production.

Hu Y, Mao K, Zeng Y, Chen S, Tao Z, Yang C, Sun S, Wu X, Meng G, Sun B.

J Immunol. 2010 Dec 15;185(12):7699-705. doi: 10.4049/jimmunol.1001099. Epub 2010 Nov 3.

PMID:
21048113
[PubMed - indexed for MEDLINE]
Free Article
8.

Mycobacterium abscessus activates the NLRP3 inflammasome via Dectin-1-Syk and p62/SQSTM1.

Lee HM, Yuk JM, Kim KH, Jang J, Kang G, Park JB, Son JW, Jo EK.

Immunol Cell Biol. 2012 Jul;90(6):601-10. doi: 10.1038/icb.2011.72. Epub 2011 Aug 30.

PMID:
21876553
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

NLRP3 inflammasome-mediated neutrophil recruitment and hypernociception depend on leukotriene B(4) in a murine model of gout.

Amaral FA, Costa VV, Tavares LD, Sachs D, Coelho FM, Fagundes CT, Soriani FM, Silveira TN, Cunha LD, Zamboni DS, Quesniaux V, Peres RS, Cunha TM, Cunha FQ, Ryffel B, Souza DG, Teixeira MM.

Arthritis Rheum. 2012 Feb;64(2):474-84. doi: 10.1002/art.33355.

PMID:
21952942
[PubMed - indexed for MEDLINE]
Free Article
10.

Apoptosis-associated speck-like protein containing a caspase recruitment domain is a regulator of procaspase-1 activation.

Stehlik C, Lee SH, Dorfleutner A, Stassinopoulos A, Sagara J, Reed JC.

J Immunol. 2003 Dec 1;171(11):6154-63.

PMID:
14634131
[PubMed - indexed for MEDLINE]
Free Article
11.

A Yersinia effector with enhanced inhibitory activity on the NF-κB pathway activates the NLRP3/ASC/caspase-1 inflammasome in macrophages.

Zheng Y, Lilo S, Brodsky IE, Zhang Y, Medzhitov R, Marcu KB, Bliska JB.

PLoS Pathog. 2011 Apr;7(4):e1002026. doi: 10.1371/journal.ppat.1002026. Epub 2011 Apr 21.

PMID:
21533069
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases.

Shio MT, Eisenbarth SC, Savaria M, Vinet AF, Bellemare MJ, Harder KW, Sutterwala FS, Bohle DS, Descoteaux A, Flavell RA, Olivier M.

PLoS Pathog. 2009 Aug;5(8):e1000559. doi: 10.1371/journal.ppat.1000559. Epub 2009 Aug 21. Erratum in: PLoS Pathog. 2009 Sep;5(9). doi: 10.1371/annotation/abca067d-b82b-4de6-93c5-0fcc38e3df05. Tiemi Shio, Marina [corrected to Shio, Marina Tiemi].

PMID:
19696895
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Differential regulation of caspase-1 activation, pyroptosis, and autophagy via Ipaf and ASC in Shigella-infected macrophages.

Suzuki T, Franchi L, Toma C, Ashida H, Ogawa M, Yoshikawa Y, Mimuro H, Inohara N, Sasakawa C, Nuñez G.

PLoS Pathog. 2007 Aug 10;3(8):e111.

PMID:
17696608
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia-reperfusion injury.

Sandanger Ø, Ranheim T, Vinge LE, Bliksøen M, Alfsnes K, Finsen AV, Dahl CP, Askevold ET, Florholmen G, Christensen G, Fitzgerald KA, Lien E, Valen G, Espevik T, Aukrust P, Yndestad A.

Cardiovasc Res. 2013 Jul 1;99(1):164-74. doi: 10.1093/cvr/cvt091. Epub 2013 Apr 10.

PMID:
23580606
[PubMed - indexed for MEDLINE]
Free Article
15.

Anti-inflammatory activity of PYNOD and its mechanism in humans and mice.

Imamura R, Wang Y, Kinoshita T, Suzuki M, Noda T, Sagara J, Taniguchi S, Okamoto H, Suda T.

J Immunol. 2010 May 15;184(10):5874-84. doi: 10.4049/jimmunol.0900779. Epub 2010 Apr 14.

PMID:
20393137
[PubMed - indexed for MEDLINE]
Free Article
16.

Tumor suppressor death-associated protein kinase is required for full IL-1β production.

Chuang YT, Lin YC, Lin KH, Chou TF, Kuo WC, Yang KT, Wu PR, Chen RH, Kimchi A, Lai MZ.

Blood. 2011 Jan 20;117(3):960-70. doi: 10.1182/blood-2010-08-303115. Epub 2010 Nov 1.

PMID:
21041719
[PubMed - indexed for MEDLINE]
Free Article
17.

NLRP3 inflammasome activation in retinal pigment epithelial cells by lysosomal destabilization: implications for age-related macular degeneration.

Tseng WA, Thein T, Kinnunen K, Lashkari K, Gregory MS, D'Amore PA, Ksander BR.

Invest Ophthalmol Vis Sci. 2013 Jan 7;54(1):110-20. doi: 10.1167/iovs.12-10655.

PMID:
23221073
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC.

Sagulenko V, Thygesen SJ, Sester DP, Idris A, Cridland JA, Vajjhala PR, Roberts TL, Schroder K, Vince JE, Hill JM, Silke J, Stacey KJ.

Cell Death Differ. 2013 Sep;20(9):1149-60. doi: 10.1038/cdd.2013.37. Epub 2013 May 3.

PMID:
23645208
[PubMed - indexed for MEDLINE]
19.

TLR-induced PAI-2 expression suppresses IL-1β processing via increasing autophagy and NLRP3 degradation.

Chuang SY, Yang CH, Chou CC, Chiang YP, Chuang TH, Hsu LC.

Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):16079-84. doi: 10.1073/pnas.1306556110. Epub 2013 Sep 16.

PMID:
24043792
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Enterohemorrhagic Escherichia coli specific enterohemolysin induced IL-1β in human macrophages and EHEC-induced IL-1β required activation of NLRP3 inflammasome.

Zhang X, Cheng Y, Xiong Y, Ye C, Zheng H, Sun H, Zhao H, Ren Z, Xu J.

PLoS One. 2012;7(11):e50288. doi: 10.1371/journal.pone.0050288. Epub 2012 Nov 27.

PMID:
23209696
[PubMed - indexed for MEDLINE]
Free PMC Article

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