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Results: 1 to 20 of 96

1.

Synthesis of micheliolide derivatives and their activities against AML progenitor cells.

Ma WW, Shi QQ, Ding YH, Long J, Zhang Q, Chen Y.

Molecules. 2013 May 21;18(5):5980-92. doi: 10.3390/molecules18055980.

PMID:
23698050
[PubMed - indexed for MEDLINE]
Free Article
2.

The application of Heck reaction in the synthesis of guaianolide sesquiterpene lactones derivatives selectively inhibiting resistant acute leukemic cells.

Ding YH, Fan HX, Long J, Zhang Q, Chen Y.

Bioorg Med Chem Lett. 2013 Nov 15;23(22):6087-92. doi: 10.1016/j.bmcl.2013.09.028. Epub 2013 Sep 14.

PMID:
24095093
[PubMed - indexed for MEDLINE]
3.

Guaianolide sesquiterpene lactones, a source to discover agents that selectively inhibit acute myelogenous leukemia stem and progenitor cells.

Zhang Q, Lu Y, Ding Y, Zhai J, Ji Q, Ma W, Yang M, Fan H, Long J, Tong Z, Shi Y, Jia Y, Han B, Zhang W, Qiu C, Ma X, Li Q, Shi Q, Zhang H, Li D, Zhang J, Lin J, Li LY, Gao Y, Chen Y.

J Med Chem. 2012 Oct 25;55(20):8757-69. doi: 10.1021/jm301064b. Epub 2012 Oct 11.

PMID:
22985027
[PubMed - indexed for MEDLINE]
4.

Reactive oxygen species-specific mechanisms of drug resistance in paraquat-resistant acute myelogenous leukemia sublines.

Choi CH, Kim HS, Kweon OS, Lee TB, You HJ, Rha HS, Jeong JH, Lim DY, Min YD, Kim MS, Chung MH.

Mol Cells. 2000 Feb 29;10(1):38-46.

PMID:
10774745
[PubMed - indexed for MEDLINE]
Free Article
5.

Resveratrol-mediated reversal of doxorubicin resistance in acute myeloid leukemia cells via downregulation of MRP1 expression.

Kweon SH, Song JH, Kim TS.

Biochem Biophys Res Commun. 2010 Apr 23;395(1):104-10. doi: 10.1016/j.bbrc.2010.03.147. Epub 2010 Mar 27.

PMID:
20350534
[PubMed - indexed for MEDLINE]
6.

Double-edged sword of chemosensitizer: increase of multidrug resistance protein (MRP) in leukemic cells by an MRP inhibitor probenecid.

Kim HS, Min YD, Choi CH.

Biochem Biophys Res Commun. 2001 Apr 27;283(1):64-71.

PMID:
11322768
[PubMed - indexed for MEDLINE]
7.

Down-regulation of catalase gene expression in the doxorubicin-resistant AML subline AML-2/DX100.

Kim HS, Lee TB, Choi CH.

Biochem Biophys Res Commun. 2001 Feb 16;281(1):109-14.

PMID:
11178967
[PubMed - indexed for MEDLINE]
8.

Antineoplastic mechanisms of niclosamide in acute myelogenous leukemia stem cells: inactivation of the NF-kappaB pathway and generation of reactive oxygen species.

Jin Y, Lu Z, Ding K, Li J, Du X, Chen C, Sun X, Wu Y, Zhou J, Pan J.

Cancer Res. 2010 Mar 15;70(6):2516-27. doi: 10.1158/0008-5472.CAN-09-3950. Epub 2010 Mar 9.

PMID:
20215516
[PubMed - indexed for MEDLINE]
Free Article
9.

Expression of multidrug resistance-associated protein (MRP) mRNA in blast cells from acute myeloid leukemia (AML) patients.

Ross DD, Doyle LA, Schiffer CA, Lee EJ, Grant CE, Cole SP, Deeley RG, Yang W, Tong Y.

Leukemia. 1996 Jan;10(1):48-55.

PMID:
8558937
[PubMed - indexed for MEDLINE]
10.

Molecular and biologic characterization and drug sensitivity of pan-histone deacetylase inhibitor-resistant acute myeloid leukemia cells.

Fiskus W, Rao R, Fernandez P, Herger B, Yang Y, Chen J, Kolhe R, Mandawat A, Wang Y, Joshi R, Eaton K, Lee P, Atadja P, Peiper S, Bhalla K.

Blood. 2008 Oct 1;112(7):2896-905. doi: 10.1182/blood-2007-10-116319. Epub 2008 Jul 25.

PMID:
18660379
[PubMed - indexed for MEDLINE]
Free Article
11.

High TRAIL-R3 expression on leukemic blasts is associated with poor outcome and induces apoptosis-resistance which can be overcome by targeting TRAIL-R2.

Chamuleau ME, Ossenkoppele GJ, van Rhenen A, van Dreunen L, Jirka SM, Zevenbergen A, Schuurhuis GJ, van de Loosdrecht AA.

Leuk Res. 2011 Jun;35(6):741-9. doi: 10.1016/j.leukres.2010.12.032. Epub 2011 Feb 1.

PMID:
21281967
[PubMed - indexed for MEDLINE]
Free Article
12.

Human stem cell factor-antibody [anti-SCF] enhances chemotherapy cytotoxicity in human CD34+ resistant myeloid leukaemia cells.

Lu C, Hassan HT.

Leuk Res. 2006 Mar;30(3):296-302. Epub 2005 Aug 19.

PMID:
16112192
[PubMed - indexed for MEDLINE]
13.

BCL-2 expression does not not correlate with patient outcome in pediatric acute myelogenous leukemia.

Naumovski L, Martinovsky G, Wong C, Chang M, Ravendranath Y, Weinstein H, Dahl G.

Leuk Res. 1998 Jan;22(1):81-7.

PMID:
9585084
[PubMed - indexed for MEDLINE]
14.

Recovery of drug sensitivity by MS-209, a new multidrug resistance-reversing agent, on acute myelogenous leukaemic blasts and K562 cells resistant to adriamycin cell line.

Wang YH, Motoji T, Motomura S, Shiozaki H, Tsuruo T, Mizoguchi H.

Eur J Haematol. 1997 Mar;58(3):186-94.

PMID:
9150713
[PubMed - indexed for MEDLINE]
15.

Multidrug resistance reverting activity and antitumor profile of new phenothiazine derivatives.

Bisi A, Meli M, Gobbi S, Rampa A, Tolomeo M, Dusonchet L.

Bioorg Med Chem. 2008 Jul 1;16(13):6474-82. doi: 10.1016/j.bmc.2008.05.040. Epub 2008 May 20.

PMID:
18522868
[PubMed - indexed for MEDLINE]
16.

Regulation of drug sensitivity by ribosomal protein S3a.

Hu ZB, Minden MD, McCulloch EA, Stahl J.

Blood. 2000 Feb 1;95(3):1047-55. Erratum in: Blood 2000 Sep 1;96(5):1632.

PMID:
10648421
[PubMed - indexed for MEDLINE]
Free Article
17.

Salinomycin overcomes ABC transporter-mediated multidrug and apoptosis resistance in human leukemia stem cell-like KG-1a cells.

Fuchs D, Daniel V, Sadeghi M, Opelz G, Naujokat C.

Biochem Biophys Res Commun. 2010 Apr 16;394(4):1098-104. doi: 10.1016/j.bbrc.2010.03.138. Epub 2010 Mar 27.

PMID:
20350531
[PubMed - indexed for MEDLINE]
19.

MEK inhibition enhances ABT-737-induced leukemia cell apoptosis via prevention of ERK-activated MCL-1 induction and modulation of MCL-1/BIM complex.

Konopleva M, Milella M, Ruvolo P, Watts JC, Ricciardi MR, Korchin B, McQueen T, Bornmann W, Tsao T, Bergamo P, Mak DH, Chen W, McCubrey J, Tafuri A, Andreeff M.

Leukemia. 2012 Apr;26(4):778-87. doi: 10.1038/leu.2011.287. Epub 2011 Nov 8.

PMID:
22064351
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Novel ROS-activated agents utilize a tethered amine to selectively target acute myeloid leukemia.

Bell-Horwath TR, Vadukoot AK, Thowfeik FS, Li G, Wunderlich M, Mulloy JC, Merino EJ.

Bioorg Med Chem Lett. 2013 May 15;23(10):2951-4. doi: 10.1016/j.bmcl.2013.03.048. Epub 2013 Mar 26.

PMID:
23578690
[PubMed - indexed for MEDLINE]
Free PMC Article
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