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Results: 1 to 20 of 124

1.

Selective roles of normal and mutant huntingtin in neural induction and early neurogenesis.

Nguyen GD, Gokhan S, Molero AE, Mehler MF.

PLoS One. 2013 May 14;8(5):e64368. doi: 10.1371/journal.pone.0064368. Print 2013.

PMID:
23691206
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Functions of huntingtin in germ layer specification and organogenesis.

Nguyen GD, Molero AE, Gokhan S, Mehler MF.

PLoS One. 2013 Aug 13;8(8):e72698. doi: 10.1371/journal.pone.0072698. eCollection 2013.

PMID:
23967334
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

The generation of definitive neural stem cells from PiggyBac transposon-induced pluripotent stem cells can be enhanced by induction of the NOTCH signaling pathway.

Salewski RP, Buttigieg J, Mitchell RA, van der Kooy D, Nagy A, Fehlings MG.

Stem Cells Dev. 2013 Feb 1;22(3):383-96. doi: 10.1089/scd.2012.0218. Epub 2012 Sep 17.

PMID:
22889305
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Multiple phenotypes in Huntington disease mouse neural stem cells.

Ritch JJ, Valencia A, Alexander J, Sapp E, Gatune L, Sangrey GR, Sinha S, Scherber CM, Zeitlin S, Sadri-Vakili G, Irimia D, Difiglia M, Kegel KB.

Mol Cell Neurosci. 2012 May;50(1):70-81. doi: 10.1016/j.mcn.2012.03.011. Epub 2012 Apr 6.

PMID:
22508027
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

FGF dependent regulation of Zfhx1b gene expression promotes the formation of definitive neural stem cells in the mouse anterior neurectoderm.

Dang LT, Tropepe V.

Neural Dev. 2010 May 6;5:13. doi: 10.1186/1749-8104-5-13.

PMID:
20459606
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Impaired mitochondrial dynamics and Nrf2 signaling contribute to compromised responses to oxidative stress in striatal cells expressing full-length mutant huntingtin.

Jin YN, Yu YV, Gundemir S, Jo C, Cui M, Tieu K, Johnson GV.

PLoS One. 2013;8(3):e57932. doi: 10.1371/journal.pone.0057932. Epub 2013 Mar 1.

PMID:
23469253
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Lack of huntingtin promotes neural stem cells differentiation into glial cells while neurons expressing huntingtin with expanded polyglutamine tracts undergo cell death.

Conforti P, Camnasio S, Mutti C, Valenza M, Thompson M, Fossale E, Zeitlin S, MacDonald ME, Zuccato C, Cattaneo E.

Neurobiol Dis. 2013 Feb;50:160-70. doi: 10.1016/j.nbd.2012.10.015. Epub 2012 Oct 23.

PMID:
23089356
[PubMed - indexed for MEDLINE]
8.

Impaired basal and running-induced hippocampal neurogenesis coincides with reduced Akt signaling in adult R6/1 HD mice.

Ransome MI, Hannan AJ.

Mol Cell Neurosci. 2013 May;54:93-107. doi: 10.1016/j.mcn.2013.01.005. Epub 2013 Feb 4.

PMID:
23384443
[PubMed - indexed for MEDLINE]
9.

Generation of neural stem cells from embryonic stem cells using the default mechanism: in vitro and in vivo characterization.

Rowland JW, Lee JJ, Salewski RP, Eftekharpour E, van der Kooy D, Fehlings MG.

Stem Cells Dev. 2011 Nov;20(11):1829-45. doi: 10.1089/scd.2011.0214. Epub 2011 Jul 5.

PMID:
21604925
[PubMed - indexed for MEDLINE]
10.

Expanded CAG repeats in the murine Huntington's disease gene increases neuronal differentiation of embryonic and neural stem cells.

Lorincz MT, Zawistowski VA.

Mol Cell Neurosci. 2009 Jan;40(1):1-13. doi: 10.1016/j.mcn.2008.06.004. Epub 2008 Jun 19.

PMID:
18625318
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Impairment of developmental stem cell-mediated striatal neurogenesis and pluripotency genes in a knock-in model of Huntington's disease.

Molero AE, Gokhan S, Gonzalez S, Feig JL, Alexandre LC, Mehler MF.

Proc Natl Acad Sci U S A. 2009 Dec 22;106(51):21900-5. doi: 10.1073/pnas.0912171106. Epub 2009 Dec 2.

PMID:
19955426
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Full length mutant huntingtin is required for altered Ca2+ signaling and apoptosis of striatal neurons in the YAC mouse model of Huntington's disease.

Zhang H, Li Q, Graham RK, Slow E, Hayden MR, Bezprozvanny I.

Neurobiol Dis. 2008 Jul;31(1):80-8. doi: 10.1016/j.nbd.2008.03.010. Epub 2008 Apr 16.

PMID:
18502655
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Specific caspase interactions and amplification are involved in selective neuronal vulnerability in Huntington's disease.

Hermel E, Gafni J, Propp SS, Leavitt BR, Wellington CL, Young JE, Hackam AS, Logvinova AV, Peel AL, Chen SF, Hook V, Singaraja R, Krajewski S, Goldsmith PC, Ellerby HM, Hayden MR, Bredesen DE, Ellerby LM.

Cell Death Differ. 2004 Apr;11(4):424-38.

PMID:
14713958
[PubMed - indexed for MEDLINE]
Free Article
14.

Neural induction intermediates exhibit distinct roles of Fgf signaling.

Sterneckert J, Stehling M, Bernemann C, Araúzo-Bravo MJ, Greber B, Gentile L, Ortmeier C, Sinn M, Wu G, Ruau D, Zenke M, Brintrup R, Klein DC, Ko K, Schöler HR.

Stem Cells. 2010 Oct;28(10):1772-81. doi: 10.1002/stem.498.

PMID:
20715182
[PubMed - indexed for MEDLINE]
Free Article
15.

LIF-dependent primitive neural stem cells derived from mouse ES cells represent a reversible stage of neural commitment.

Tsang WH, Wang B, Wong WK, Shi S, Chen X, He X, Gu S, Hu J, Wang C, Liu PC, Lu G, Chen X, Zhao H, Poon WS, Chan WY, Feng B.

Stem Cell Res. 2013 Nov;11(3):1091-102. doi: 10.1016/j.scr.2013.07.007. Epub 2013 Aug 2.

PMID:
23973799
[PubMed - indexed for MEDLINE]
16.

AP2γ regulates neural and epidermal development downstream of the BMP pathway at early stages of ectodermal patterning.

Qiao Y, Zhu Y, Sheng N, Chen J, Tao R, Zhu Q, Zhang T, Qian C, Jing N.

Cell Res. 2012 Nov;22(11):1546-61. doi: 10.1038/cr.2012.122. Epub 2012 Sep 4.

PMID:
22945355
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

An evolutionary recent neuroepithelial cell adhesion function of huntingtin implicates ADAM10-Ncadherin.

Lo Sardo V, Zuccato C, Gaudenzi G, Vitali B, Ramos C, Tartari M, Myre MA, Walker JA, Pistocchi A, Conti L, Valenza M, Drung B, Schmidt B, Gusella J, Zeitlin S, Cotelli F, Cattaneo E.

Nat Neurosci. 2012 May;15(5):713-21. doi: 10.1038/nn.3080.

PMID:
22466506
[PubMed - indexed for MEDLINE]
18.

Neuronal vs. glial fate of embryonic stem cell-derived neural progenitors (ES-NPs) is determined by FGF2/EGF during proliferation.

Sanalkumar R, Vidyanand S, Lalitha Indulekha C, James J.

J Mol Neurosci. 2010 Sep;42(1):17-27. doi: 10.1007/s12031-010-9335-z. Epub 2010 Feb 13.

PMID:
20155332
[PubMed - indexed for MEDLINE]
19.

Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice.

Gray M, Shirasaki DI, Cepeda C, André VM, Wilburn B, Lu XH, Tao J, Yamazaki I, Li SH, Sun YE, Li XJ, Levine MS, Yang XW.

J Neurosci. 2008 Jun 11;28(24):6182-95. doi: 10.1523/JNEUROSCI.0857-08.2008.

PMID:
18550760
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

The apical polarity determinant Crumbs 2 is a novel regulator of ESC-derived neural progenitors.

Boroviak T, Rashbass P.

Stem Cells. 2011 Feb;29(2):193-205. doi: 10.1002/stem.567.

PMID:
21732478
[PubMed - indexed for MEDLINE]
Free Article

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