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Items: 1 to 20 of 164

1.

Autophagy inhibition rescues against leptin-induced cardiac contractile dysfunction.

Kandadi MR, Roe ND, Ren J.

Curr Pharm Des. 2014;20(4):675-83.

PMID:
23688013
2.
3.

Deletion of protein tyrosine phosphatase 1B rescues against myocardial anomalies in high fat diet-induced obesity: Role of AMPK-dependent autophagy.

Kandadi MR, Panzhinskiy E, Roe ND, Nair S, Hu D, Sun A.

Biochim Biophys Acta. 2015 Feb;1852(2):299-309. doi: 10.1016/j.bbadis.2014.07.004. Epub 2014 Jul 10.

4.

A novel protective mechanism for mitochondrial aldehyde dehydrogenase (ALDH2) in type i diabetes-induced cardiac dysfunction: role of AMPK-regulated autophagy.

Guo Y, Yu W, Sun D, Wang J, Li C, Zhang R, Babcock SA, Li Y, Liu M, Ma M, Shen M, Zeng C, Li N, He W, Zou Q, Zhang Y, Wang H.

Biochim Biophys Acta. 2015 Feb;1852(2):319-31. doi: 10.1016/j.bbadis.2014.05.017. Epub 2014 May 27.

5.

Targeted deletion of PTEN in cardiomyocytes renders cardiac contractile dysfunction through interruption of Pink1-AMPK signaling and autophagy.

Roe ND, Xu X, Kandadi MR, Hu N, Pang J, Weiser-Evans MC, Ren J.

Biochim Biophys Acta. 2015 Feb;1852(2):290-8. doi: 10.1016/j.bbadis.2014.09.002. Epub 2014 Sep 16.

6.

Inhibition of AMPK accentuates prolonged caloric restriction-induced change in cardiac contractile function through disruption of compensatory autophagy.

Zheng Q, Zhao K, Han X, Huff AF, Cui Q, Babcock SA, Yu S, Zhang Y.

Biochim Biophys Acta. 2015 Feb;1852(2):332-42. doi: 10.1016/j.bbadis.2014.04.023. Epub 2014 May 2.

7.

Deficiency in AMPK attenuates ethanol-induced cardiac contractile dysfunction through inhibition of autophagosome formation.

Guo R, Ren J.

Cardiovasc Res. 2012 Jun 1;94(3):480-91. doi: 10.1093/cvr/cvs127. Epub 2012 Mar 26.

8.

Cardiomyocyte-specific deletion of endothelin receptor A rescues aging-associated cardiac hypertrophy and contractile dysfunction: role of autophagy.

Ceylan-Isik AF, Dong M, Zhang Y, Dong F, Turdi S, Nair S, Yanagisawa M, Ren J.

Basic Res Cardiol. 2013 Mar;108(2):335. doi: 10.1007/s00395-013-0335-3. Epub 2013 Feb 5.

9.

AMP-activated protein kinase deficiency rescues paraquat-induced cardiac contractile dysfunction through an autophagy-dependent mechanism.

Wang Q, Yang L, Hua Y, Nair S, Xu X, Ren J.

Toxicol Sci. 2014 Nov;142(1):6-20. doi: 10.1093/toxsci/kfu158. Epub 2014 Aug 4.

10.

Facilitated ethanol metabolism promotes cardiomyocyte contractile dysfunction through autophagy in murine hearts.

Guo R, Hu N, Kandadi MR, Ren J.

Autophagy. 2012 Apr;8(4):593-608. doi: 10.4161/auto.18997. Epub 2012 Apr 1.

11.

Cardiac overexpression of metallothionein rescues cardiac contractile dysfunction and endoplasmic reticulum stress but not autophagy in sepsis.

Ceylan-Isik AF, Zhao P, Zhang B, Xiao X, Su G, Ren J.

J Mol Cell Cardiol. 2010 Feb;48(2):367-78. doi: 10.1016/j.yjmcc.2009.11.003. Epub 2009 Nov 13.

12.

Antioxidant catalase rescues against high fat diet-induced cardiac dysfunction via an IKK╬▓-AMPK-dependent regulation of autophagy.

Liang L, Shou XL, Zhao HK, Ren GQ, Wang JB, Wang XH, Ai WT, Maris JR, Hueckstaedt LK, Ma AQ, Zhang Y.

Biochim Biophys Acta. 2015 Feb;1852(2):343-52. doi: 10.1016/j.bbadis.2014.06.027. Epub 2014 Jun 30.

13.

AMP-dependent kinase and autophagic flux are involved in aldehyde dehydrogenase-2-induced protection against cardiac toxicity of ethanol.

Ge W, Guo R, Ren J.

Free Radic Biol Med. 2011 Nov 1;51(9):1736-48. doi: 10.1016/j.freeradbiomed.2011.08.002. Epub 2011 Aug 10.

14.

Cold stress accentuates pressure overload-induced cardiac hypertrophy and contractile dysfunction: role of TRPV1/AMPK-mediated autophagy.

Lu S, Xu D.

Biochem Biophys Res Commun. 2013 Dec 6;442(1-2):8-15. doi: 10.1016/j.bbrc.2013.10.128. Epub 2013 Nov 5.

PMID:
24211590
15.

Toll-like receptor 4 knockout protects against anthrax lethal toxin-induced cardiac contractile dysfunction: role of autophagy.

Kandadi MR, Frankel AE, Ren J.

Br J Pharmacol. 2012 Oct;167(3):612-26. doi: 10.1111/j.1476-5381.2012.02040.x.

16.

Heavy metal scavenger metallothionein mitigates deep hypothermia-induced myocardial contractile anomalies: role of autophagy.

Jiang S, Guo R, Zhang Y, Zou Y, Ren J.

Am J Physiol Endocrinol Metab. 2013 Jan 1;304(1):E74-86. doi: 10.1152/ajpendo.00176.2012. Epub 2012 Nov 6.

17.

Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy.

Matsui Y, Takagi H, Qu X, Abdellatif M, Sakoda H, Asano T, Levine B, Sadoshima J.

Circ Res. 2007 Mar 30;100(6):914-22. Epub 2007 Mar 1.

18.

Mitochondrial aldehyde dehydrogenase obliterates endoplasmic reticulum stress-induced cardiac contractile dysfunction via correction of autophagy.

Zhang B, Zhang Y, La Cour KH, Richmond KL, Wang XM, Ren J.

Biochim Biophys Acta. 2013 Apr;1832(4):574-84. doi: 10.1016/j.bbadis.2013.01.013. Epub 2013 Jan 23.

19.

Suppression of autophagy is protective in high glucose-induced cardiomyocyte injury.

Kobayashi S, Xu X, Chen K, Liang Q.

Autophagy. 2012 Apr;8(4):577-92. doi: 10.4161/auto.18980. Epub 2012 Apr 1.

20.

Aldehyde dehydrogenase 2 ameliorates doxorubicin-induced myocardial dysfunction through detoxification of 4-HNE and suppression of autophagy.

Sun A, Cheng Y, Zhang Y, Zhang Q, Wang S, Tian S, Zou Y, Hu K, Ren J, Ge J.

J Mol Cell Cardiol. 2014 Jun;71:92-104. doi: 10.1016/j.yjmcc.2014.01.002. Epub 2014 Jan 13.

PMID:
24434637
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