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Results: 1 to 20 of 113

1.

Interaction between the TP63 and SHH pathways is an important determinant of epidermal homeostasis.

Chari NS, Romano RA, Koster MI, Jaks V, Roop D, Flores ER, Teglund S, Sinha S, Gruber W, Aberger F, Medeiros LJ, Toftgard R, McDonnell TJ.

Cell Death Differ. 2013 Aug;20(8):1080-8. doi: 10.1038/cdd.2013.41. Epub 2013 May 17.

PMID:
23686138
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved.

Chen MH, Wilson CW, Li YJ, Law KK, Lu CS, Gacayan R, Zhang X, Hui CC, Chuang PT.

Genes Dev. 2009 Aug 15;23(16):1910-28. doi: 10.1101/gad.1794109.

PMID:
19684112
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Differential regulation of Gli proteins by Sufu in the lung affects PDGF signaling and myofibroblast development.

Lin C, Chen MH, Yao E, Song H, Gacayan R, Hui CC, Chuang PT.

Dev Biol. 2014 Aug 15;392(2):324-33. doi: 10.1016/j.ydbio.2014.05.014. Epub 2014 Jun 2.

PMID:
24886827
[PubMed - indexed for MEDLINE]
4.

Induction of basal cell carcinoma features in transgenic human skin expressing Sonic Hedgehog.

Fan H, Oro AE, Scott MP, Khavari PA.

Nat Med. 1997 Jul;3(7):788-92.

PMID:
9212109
[PubMed - indexed for MEDLINE]
5.

p63/p51-induced onset of keratinocyte differentiation via the c-Jun N-terminal kinase pathway is counteracted by keratinocyte growth factor.

Ogawa E, Okuyama R, Egawa T, Nagoshi H, Obinata M, Tagami H, Ikawa S, Aiba S.

J Biol Chem. 2008 Dec 5;283(49):34241-9. doi: 10.1074/jbc.M804101200. Epub 2008 Oct 10.

PMID:
18849344
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Suppressor of fused is required to maintain the multipotency of neural progenitor cells in the retina.

Cwinn MA, Mazerolle C, McNeill B, Ringuette R, Thurig S, Hui CC, Wallace VA.

J Neurosci. 2011 Mar 30;31(13):5169-80. doi: 10.1523/JNEUROSCI.5495-10.2011.

PMID:
21451052
[PubMed - indexed for MEDLINE]
Free Article
7.

Dynamic life of a skin keratinocyte: an intimate tryst with the master regulator p63.

Romano RA, Sinha S.

Indian J Exp Biol. 2011 Oct;49(10):721-31. Review.

PMID:
22013738
[PubMed - indexed for MEDLINE]
8.

Kif7 regulates Gli2 through Sufu-dependent and -independent functions during skin development and tumorigenesis.

Li ZJ, Nieuwenhuis E, Nien W, Zhang X, Zhang J, Puviindran V, Wainwright BJ, Kim PC, Hui CC.

Development. 2012 Nov;139(22):4152-61. doi: 10.1242/dev.081190. Epub 2012 Oct 3.

PMID:
23034632
[PubMed - indexed for MEDLINE]
Free Article
9.

deltaNp63alpha functions as both a positive and a negative transcriptional regulator and blocks in vitro differentiation of murine keratinocytes.

King KE, Ponnamperuma RM, Yamashita T, Tokino T, Lee LA, Young MF, Weinberg WC.

Oncogene. 2003 Jun 5;22(23):3635-44.

PMID:
12789272
[PubMed - indexed for MEDLINE]
10.

Unique domain functions of p63 isotypes that differentially regulate distinct aspects of epidermal homeostasis.

King KE, Ponnamperuma RM, Gerdes MJ, Tokino T, Yamashita T, Baker CC, Weinberg WC.

Carcinogenesis. 2006 Jan;27(1):53-63. Epub 2005 Aug 4.

PMID:
16081516
[PubMed - indexed for MEDLINE]
Free Article
11.

Novel mechanism of action on Hedgehog signaling by a suppressor of fused carboxy terminal variant.

Tostar U, Finta C, Rahman MF, Shimokawa T, Zaphiropoulos PG.

PLoS One. 2012;7(5):e37761. doi: 10.1371/journal.pone.0037761. Epub 2012 May 29.

PMID:
22666390
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Epidermal growth factor receptor signaling synergizes with Hedgehog/GLI in oncogenic transformation via activation of the MEK/ERK/JUN pathway.

Schnidar H, Eberl M, Klingler S, Mangelberger D, Kasper M, Hauser-Kronberger C, Regl G, Kroismayr R, Moriggl R, Sibilia M, Aberger F.

Cancer Res. 2009 Feb 15;69(4):1284-92. doi: 10.1158/0008-5472.CAN-08-2331. Epub 2009 Feb 3.

PMID:
19190345
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Activation of the BCL2 promoter in response to Hedgehog/GLI signal transduction is predominantly mediated by GLI2.

Regl G, Kasper M, Schnidar H, Eichberger T, Neill GW, Philpott MP, Esterbauer H, Hauser-Kronberger C, Frischauf AM, Aberger F.

Cancer Res. 2004 Nov 1;64(21):7724-31.

PMID:
15520176
[PubMed - indexed for MEDLINE]
Free Article
14.

Genetic elimination of Suppressor of fused reveals an essential repressor function in the mammalian Hedgehog signaling pathway.

Svärd J, Heby-Henricson K, Persson-Lek M, Rozell B, Lauth M, Bergström A, Ericson J, Toftgård R, Teglund S.

Dev Cell. 2006 Feb;10(2):187-97. Erratum in: Dev Cell. 2006 Mar;10(3):409. Henricson, Karin Heby [corrected to Heby-Henricson, Karin].

PMID:
16459298
[PubMed - indexed for MEDLINE]
Free Article
15.

Tumor-specific p73 up-regulation mediates p63 dependence in squamous cell carcinoma.

DeYoung MP, Johannessen CM, Leong CO, Faquin W, Rocco JW, Ellisen LW.

Cancer Res. 2006 Oct 1;66(19):9362-8.

PMID:
17018588
[PubMed - indexed for MEDLINE]
Free Article
16.

Overexpression of hedgehog signaling is associated with epidermal tumor formation in vitamin D receptor-null mice.

Teichert AE, Elalieh H, Elias PM, Welsh J, Bikle DD.

J Invest Dermatol. 2011 Nov;131(11):2289-97. doi: 10.1038/jid.2011.196. Epub 2011 Aug 4.

PMID:
21814234
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors.

Liu A, Wang B, Niswander LA.

Development. 2005 Jul;132(13):3103-11. Epub 2005 Jun 1.

PMID:
15930098
[PubMed - indexed for MEDLINE]
Free Article
18.

14-3-3σ and p63 play opposing roles in epidermal tumorigenesis.

Li Q, Sambandam SA, Lu HJ, Thomson A, Kim SH, Lu H, Xin Y, Lu Q.

Carcinogenesis. 2011 Dec;32(12):1782-8. doi: 10.1093/carcin/bgr207. Epub 2011 Sep 16.

PMID:
21926108
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Antagonistic and cooperative actions of Kif7 and Sufu define graded intracellular Gli activities in Hedgehog signaling.

Law KK, Makino S, Mo R, Zhang X, Puviindran V, Hui CC.

PLoS One. 2012;7(11):e50193. doi: 10.1371/journal.pone.0050193. Epub 2012 Nov 16.

PMID:
23166838
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Cardiac and CNS defects in a mouse with targeted disruption of suppressor of fused.

Cooper AF, Yu KP, Brueckner M, Brailey LL, Johnson L, McGrath JM, Bale AE.

Development. 2005 Oct;132(19):4407-17.

PMID:
16155214
[PubMed - indexed for MEDLINE]
Free Article

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