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Results: 1 to 20 of 131

1.

A genetic screen identifies TCF3/E2A and TRIAP1 as pathway-specific regulators of the cellular response to p53 activation.

Andrysik Z, Kim J, Tan AC, Espinosa JM.

Cell Rep. 2013 May 30;3(5):1346-54. doi: 10.1016/j.celrep.2013.04.014. Epub 2013 May 16.

PMID:
23684607
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Systematic genetic dissection of p14ARF-mediated mitochondrial cell death signaling reveals a key role for p21CDKN1 and the BH3-only protein Puma/bbc3.

Hemmati PG, Müer A, Gillissen B, Overkamp T, Milojkovic A, Wendt J, Dörken B, Daniel PT.

J Mol Med (Berl). 2010 Jun;88(6):609-22. doi: 10.1007/s00109-010-0606-5. Epub 2010 Apr 25.

PMID:
20419447
[PubMed - indexed for MEDLINE]
3.

p53-Dependent p21-mediated growth arrest pre-empts and protects HCT116 cells from PUMA-mediated apoptosis induced by EGCG.

Thakur VS, Ruhul Amin AR, Paul RK, Gupta K, Hastak K, Agarwal MK, Jackson MW, Wald DN, Mukhtar H, Agarwal ML.

Cancer Lett. 2010 Oct 28;296(2):225-32. doi: 10.1016/j.canlet.2010.04.012. Epub 2010 May 4.

PMID:
20444544
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

p53 efficiently suppresses tumor development in the complete absence of its cell-cycle inhibitory and proapoptotic effectors p21, Puma, and Noxa.

Valente LJ, Gray DH, Michalak EM, Pinon-Hofbauer J, Egle A, Scott CL, Janic A, Strasser A.

Cell Rep. 2013 May 30;3(5):1339-45. doi: 10.1016/j.celrep.2013.04.012. Epub 2013 May 9.

PMID:
23665218
[PubMed - indexed for MEDLINE]
Free Article
5.

Putting the brakes on p53-driven apoptosis.

Höpker K, Hagmann H, Khurshid S, Chen S, Schermer B, Benzing T, Reinhardt HC.

Cell Cycle. 2012 Nov 15;11(22):4122-8. doi: 10.4161/cc.21997. Epub 2012 Sep 14.

PMID:
22983126
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

TRIM8 modulates p53 activity to dictate cell cycle arrest.

Caratozzolo MF, Micale L, Turturo MG, Cornacchia S, Fusco C, Marzano F, Augello B, D'Erchia AM, Guerrini L, Pesole G, Sbisà E, Merla G, Tullo A.

Cell Cycle. 2012 Feb 1;11(3):511-23. doi: 10.4161/cc.11.3.19008. Epub 2012 Feb 1.

PMID:
22262183
[PubMed - indexed for MEDLINE]
7.

SKIP counteracts p53-mediated apoptosis via selective regulation of p21Cip1 mRNA splicing.

Chen Y, Zhang L, Jones KA.

Genes Dev. 2011 Apr 1;25(7):701-16. doi: 10.1101/gad.2002611.

PMID:
21460037
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

The p53-p21WAF1 checkpoint pathway plays a protective role in preventing DNA rereplication induced by abrogation of FOXF1 function.

Lo PK, Lee JS, Sukumar S.

Cell Signal. 2012 Jan;24(1):316-24. doi: 10.1016/j.cellsig.2011.09.017. Epub 2011 Sep 22.

PMID:
21964066
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

LYG-202 inhibits the proliferation of human colorectal carcinoma HCT-116 cells through induction of G1/S cell cycle arrest and apoptosis via p53 and p21(WAF1/Cip1) expression.

Liu W, Dai Q, Lu N, Wei L, Ha J, Rong J, Mu R, You Q, Li Z, Guo Q.

Biochem Cell Biol. 2011 Jun;89(3):287-98. doi: 10.1139/O10-162. Epub 2011 Apr 14.

PMID:
21491996
[PubMed - indexed for MEDLINE]
10.

Chromium-mediated apoptosis: involvement of DNA-dependent protein kinase (DNA-PK) and differential induction of p53 target genes.

Hill R, Leidal AM, Madureira PA, Gillis LD, Waisman DM, Chiu A, Lee PW.

DNA Repair (Amst). 2008 Sep 1;7(9):1484-99. doi: 10.1016/j.dnarep.2008.05.007. Epub 2008 Jul 7. Erratum in: DNA Repair (Amst). 2013 Oct;12(10):870.

PMID:
18602874
[PubMed - indexed for MEDLINE]
11.

Human rpL3 induces G₁/S arrest or apoptosis by modulating p21 (waf1/cip1) levels in a p53-independent manner.

Russo A, Esposito D, Catillo M, Pietropaolo C, Crescenzi E, Russo G.

Cell Cycle. 2013 Jan 1;12(1):76-87. doi: 10.4161/cc.22963. Epub 2012 Dec 19.

PMID:
23255119
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

c-ABL tyrosine kinase modulates p53-dependent p21 induction and ensuing cell fate decision in response to DNA damage.

Udden SM, Morita-Fujimura Y, Satake M, Ikawa S.

Cell Signal. 2014 Feb;26(2):444-52. doi: 10.1016/j.cellsig.2013.10.005. Epub 2013 Oct 28.

PMID:
24177958
[PubMed - indexed for MEDLINE]
13.

Identification of HEXIM1 as a positive regulator of p53.

Lew QJ, Chia YL, Chu KL, Lam YT, Gurumurthy M, Xu S, Lam KP, Cheong N, Chao SH.

J Biol Chem. 2012 Oct 19;287(43):36443-54. doi: 10.1074/jbc.M112.374157. Epub 2012 Sep 4.

PMID:
22948151
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Puma and p21 represent cooperating checkpoints limiting self-renewal and chromosomal instability of somatic stem cells in response to telomere dysfunction.

Sperka T, Song Z, Morita Y, Nalapareddy K, Guachalla LM, Lechel A, Begus-Nahrmann Y, Burkhalter MD, Mach M, Schlaudraff F, Liss B, Ju Z, Speicher MR, Rudolph KL.

Nat Cell Biol. 2011 Dec 4;14(1):73-9. doi: 10.1038/ncb2388.

PMID:
22138576
[PubMed - indexed for MEDLINE]
15.

TAT-RasGAP317-326 requires p53 and PUMA to sensitize tumor cells to genotoxins.

Michod D, Widmann C.

Mol Cancer Res. 2007 May;5(5):497-507.

PMID:
17510315
[PubMed - indexed for MEDLINE]
Free Article
16.

The histone acetyltransferase PCAF regulates p21 transcription through stress-induced acetylation of histone H3.

Love IM, Sekaric P, Shi D, Grossman SR, Androphy EJ.

Cell Cycle. 2012 Jul 1;11(13):2458-66. doi: 10.4161/cc.20864. Epub 2012 Jul 1.

PMID:
22713239
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Selenoprotein W depletion induces a p53- and p21-dependent delay in cell cycle progression in RWPE-1 prostate epithelial cells.

Hawkes WC, Printsev I, Alkan Z.

J Cell Biochem. 2012 Jan;113(1):61-9. doi: 10.1002/jcb.23328.

PMID:
21866568
[PubMed - indexed for MEDLINE]
18.

Cyclin-dependent kinase inhibitors uncouple cell cycle progression from mitochondrial apoptotic functions in DNA-damaged cancer cells.

Le HV, Minn AJ, Massagué J.

J Biol Chem. 2005 Sep 9;280(36):32018-25. Epub 2005 Jul 6.

PMID:
16002406
[PubMed - indexed for MEDLINE]
Free Article
19.

p21(WAF1) is component of a positive feedback loop that maintains the p53 transcriptional program.

Pang LY, Scott M, Hayward RL, Mohammed H, Whitelaw CB, Smith GC, Hupp TR.

Cell Cycle. 2011 Mar 15;10(6):932-50. Epub 2011 Mar 15.

PMID:
21368573
[PubMed - indexed for MEDLINE]
Free Article
20.

Gene-specific repression of the p53 target gene PUMA via intragenic CTCF-Cohesin binding.

Gomes NP, Espinosa JM.

Genes Dev. 2010 May 15;24(10):1022-34. doi: 10.1101/gad.1881010.

PMID:
20478995
[PubMed - indexed for MEDLINE]
Free PMC Article

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