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Results: 1 to 20 of 121

1.

Beneficial effects of histone deacetylase inhibition with severe hemorrhage and ischemia-reperfusion injury.

Causey MW, Miller S, Hoffer Z, Hempel J, Stallings JD, Jin G, Alam H, Martin M.

J Surg Res. 2013 Sep;184(1):533-40. doi: 10.1016/j.jss.2013.03.087. Epub 2013 Apr 17.

PMID:
23683808
[PubMed - indexed for MEDLINE]
2.

Flutamide fails to reduce resuscitation requirements in a porcine ischemia-reperfusion model.

Satterly SA, Martin M, Wingerd M, Hempel J, Hoffer Z, Stallings JD.

J Surg Res. 2013 Sep;184(1):472-9. doi: 10.1016/j.jss.2013.04.083. Epub 2013 Jun 3.

PMID:
23791438
[PubMed - indexed for MEDLINE]
3.

Valproic acid reversed pathologic endothelial cell gene expression profile associated with ischemia-reperfusion injury in a swine hemorrhagic shock model.

Causey MW, Salgar S, Singh N, Martin M, Stallings JD.

J Vasc Surg. 2012 Apr;55(4):1096-1103.e51. doi: 10.1016/j.jvs.2011.08.060. Epub 2011 Nov 21.

PMID:
22100532
[PubMed - indexed for MEDLINE]
Free Article
4.

Effects of histone deacetylase inhibition on 24-hour survival and end-organ injury in a porcine trauma model: a prospective, randomized trial.

Nelson DW, Porta CR, McVay DP, Salgar SK, Martin MJ.

J Trauma Acute Care Surg. 2013 Dec;75(6):1031-9. doi: 10.1097/TA.0b013e31829d01bf.

PMID:
24256678
[PubMed - indexed for MEDLINE]
5.

Pharmacologic resuscitation: cell protective mechanisms of histone deacetylase inhibition in lethal hemorrhagic shock.

Butt MU, Sailhamer EA, Li Y, Liu B, Shuja F, Velmahos GC, DeMoya M, King DR, Alam HB.

J Surg Res. 2009 Oct;156(2):290-6. doi: 10.1016/j.jss.2009.04.012. Epub 2009 May 13.

PMID:
19665733
[PubMed - indexed for MEDLINE]
6.

Surviving blood loss without blood transfusion in a swine poly-trauma model.

Alam HB, Shuja F, Butt MU, Duggan M, Li Y, Zacharias N, Fukudome EY, Liu B, Demoya M, Velmahos GC.

Surgery. 2009 Aug;146(2):325-33. doi: 10.1016/j.surg.2009.04.007. Epub 2009 Jun 25.

PMID:
19628092
[PubMed - indexed for MEDLINE]
7.

Valproic acid-mediated neuroprotection in retinal ischemia injury via histone deacetylase inhibition and transcriptional activation.

Zhang Z, Qin X, Tong N, Zhao X, Gong Y, Shi Y, Wu X.

Exp Eye Res. 2012 Jan;94(1):98-108. doi: 10.1016/j.exer.2011.11.013. Epub 2011 Nov 28.

PMID:
22143029
[PubMed - indexed for MEDLINE]
8.

Treatment with a histone deacetylase inhibitor, valproic acid, is associated with increased platelet activation in a large animal model of traumatic brain injury and hemorrhagic shock.

Dekker SE, Sillesen M, Bambakidis T, Andjelkovic AV, Jin G, Liu B, Boer C, Johansson PI, Linzel D, Halaweish I, Alam HB.

J Surg Res. 2014 Jul;190(1):312-8. doi: 10.1016/j.jss.2014.02.049. Epub 2014 Mar 1.

PMID:
24694719
[PubMed - indexed for MEDLINE]
9.

[The effects of administration of valproic acid on organ function and outcome in a canine lethal hemorrhagic shock model].

Hu S, Hou JY, Li L, Yang MX, Sheng ZY.

Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2011 Aug;23(8):471-4. Chinese.

PMID:
21878170
[PubMed - indexed for MEDLINE]
Free Article
10.

Pharmacologic resuscitation for hemorrhagic shock combined with traumatic brain injury.

Jin G, Duggan M, Imam A, Demoya MA, Sillesen M, Hwabejire J, Jepsen CH, Liu B, Mejaddam AY, Lu J, Smith WM, Velmahos GC, Socrate S, Alam HB.

J Trauma Acute Care Surg. 2012 Dec;73(6):1461-70. doi: 10.1097/TA.0b013e3182782641.

PMID:
23188239
[PubMed - indexed for MEDLINE]
11.

Hepatoprotection and lethality rescue by histone deacetylase inhibitor valproic acid in fatal hemorrhagic shock.

Gonzales ER, Chen H, Munuve RM, Mehrani T, Nadel A, Koustova E.

J Trauma. 2008 Sep;65(3):554-65. doi: 10.1097/TA.0b013e31818233ef.

PMID:
18784568
[PubMed - indexed for MEDLINE]
12.

Valproate protects the retina from endoplasmic reticulum stress-induced apoptosis after ischemia-reperfusion injury.

Zhang Z, Tong N, Gong Y, Qiu Q, Yin L, Lv X, Wu X.

Neurosci Lett. 2011 Oct 24;504(2):88-92. doi: 10.1016/j.neulet.2011.09.003. Epub 2011 Sep 12.

PMID:
21939735
[PubMed - indexed for MEDLINE]
13.

Pharmacologic resuscitation promotes survival and attenuates hemorrhage-induced activation of extracellular signal-regulated kinase 1/2.

Fukudome EY, Kochanek AR, Li Y, Smith EJ, Liu B, Kheirbek T, Lu J, Kim K, Hamwi K, Velmahos GC, Alam HB.

J Surg Res. 2010 Sep;163(1):118-26. doi: 10.1016/j.jss.2010.04.013. Epub 2010 May 7.

PMID:
20599213
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Histone deacetylase inhibitors prevent apoptosis following lethal hemorrhagic shock in rodent kidney cells.

Zacharias N, Sailhamer EA, Li Y, Liu B, Butt MU, Shuja F, Velmahos GC, de Moya M, Alam HB.

Resuscitation. 2011 Jan;82(1):105-9. doi: 10.1016/j.resuscitation.2010.09.469. Epub 2010 Oct 30.

PMID:
21036453
[PubMed - indexed for MEDLINE]
15.

Histone deacetylase as therapeutic target in a rodent model of hemorrhagic shock: effect of different resuscitation strategies on lung and liver.

Lin T, Chen H, Koustova E, Sailhamer EA, Li Y, Shults C, Liu B, Rhee P, Kirkpatrick J, Alam HB.

Surgery. 2007 Jun;141(6):784-94.

PMID:
17560255
[PubMed - indexed for MEDLINE]
16.

Pharmacologic resuscitation decreases circulating cytokine-induced neutrophil chemoattractant-1 levels and attenuates hemorrhage-induced acute lung injury.

Fukudome EY, Li Y, Kochanek AR, Lu J, Smith EJ, Liu B, Kim K, Velmahos GC, deMoya MA, Alam HB.

Surgery. 2012 Aug;152(2):254-61. doi: 10.1016/j.surg.2012.03.013. Epub 2012 May 30.

PMID:
22657731
[PubMed - indexed for MEDLINE]
17.

[Protective effect of valproic acid on ischemia-reperfusion induced injury in retina of rat].

Zhang ZZ, Wu XW, Gong YY, Zhang W, Yin LL.

Zhonghua Yan Ke Za Zhi. 2012 Aug;48(8):739-43. Chinese.

PMID:
23141516
[PubMed - indexed for MEDLINE]
18.

Histone deacetylase inhibitor treatment attenuates MAP kinase pathway activation and pulmonary inflammation following hemorrhagic shock in a rodent model.

Kochanek AR, Fukudome EY, Li Y, Smith EJ, Liu B, Velmahos GC, deMoya M, King D, Alam HB.

J Surg Res. 2012 Jul;176(1):185-94. doi: 10.1016/j.jss.2011.06.007. Epub 2011 Jul 5.

PMID:
21816439
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

The protective effects of 17beta-estradiol on hepatic ischemia-reperfusion injury in rat model, associated with regulation of heat-shock protein expression.

Shen SQ, Zhang Y, Xiong CL.

J Surg Res. 2007 Jun 1;140(1):67-76. Epub 2007 Mar 2.

PMID:
17336333
[PubMed - indexed for MEDLINE]
20.

The effects of tranexamic acid and prothrombin complex concentrate on the coagulopathy of trauma: an in vitro analysis of the impact of severe acidosis.

Porta CR, Nelson D, McVay D, Salgar S, Eckert M, Izenberg S, Martin MJ.

J Trauma Acute Care Surg. 2013 Dec;75(6):954-60. doi: 10.1097/TA.0b013e31829e20bf.

PMID:
24256666
[PubMed - indexed for MEDLINE]

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