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Items: 1 to 20 of 230


Upregulation of CHOP/GADD153 during coronavirus infectious bronchitis virus infection modulates apoptosis by restricting activation of the extracellular signal-regulated kinase pathway.

Liao Y, Fung TS, Huang M, Fang SG, Zhong Y, Liu DX.

J Virol. 2013 Jul;87(14):8124-34. doi: 10.1128/JVI.00626-13. Epub 2013 May 15.


Up-regulation of Mcl-1 and Bak by coronavirus infection of human, avian and animal cells modulates apoptosis and viral replication.

Zhong Y, Liao Y, Fang S, Tam JP, Liu DX.

PLoS One. 2012;7(1):e30191. doi: 10.1371/journal.pone.0030191. Epub 2012 Jan 11.


The endoplasmic reticulum stress sensor IRE1α protects cells from apoptosis induced by the coronavirus infectious bronchitis virus.

Fung TS, Liao Y, Liu DX.

J Virol. 2014 Nov;88(21):12752-64. doi: 10.1128/JVI.02138-14. Epub 2014 Aug 20.


PKCδ regulates death receptor 5 expression induced by PS-341 through ATF4-ATF3/CHOP axis in human lung cancer cells.

Xu L, Su L, Liu X.

Mol Cancer Ther. 2012 Oct;11(10):2174-82. doi: 10.1158/1535-7163.MCT-12-0602. Epub 2012 Jul 30.


Saturated fatty acid induction of endoplasmic reticulum stress and apoptosis in human liver cells via the PERK/ATF4/CHOP signaling pathway.

Cao J, Dai DL, Yao L, Yu HH, Ning B, Zhang Q, Chen J, Cheng WH, Shen W, Yang ZX.

Mol Cell Biochem. 2012 May;364(1-2):115-29. doi: 10.1007/s11010-011-1211-9. Epub 2012 Jan 15.


Translational and posttranslational regulation of XIAP by eIF2α and ATF4 promotes ER stress-induced cell death during the unfolded protein response.

Hiramatsu N, Messah C, Han J, LaVail MM, Kaufman RJ, Lin JH.

Mol Biol Cell. 2014 May;25(9):1411-20. doi: 10.1091/mbc.E13-11-0664. Epub 2014 Mar 12.


Endoplasmic reticulum stress signaling is involved in mitomycin C (MMC)-induced apoptosis in human fibroblasts via PERK pathway.

Shi K, Wang D, Cao X, Ge Y.

PLoS One. 2013;8(3):e59330. doi: 10.1371/journal.pone.0059330. Epub 2013 Mar 22.


Enhanced selenium effect on growth arrest by BiP/GRP78 knockdown in p53-null human prostate cancer cells.

Zu K, Bihani T, Lin A, Park YM, Mori K, Ip C.

Oncogene. 2006 Jan 26;25(4):546-54.


Coxsackievirus B3 infection activates the unfolded protein response and induces apoptosis through downregulation of p58IPK and activation of CHOP and SREBP1.

Zhang HM, Ye X, Su Y, Yuan J, Liu Z, Stein DA, Yang D.

J Virol. 2010 Sep;84(17):8446-59. doi: 10.1128/JVI.01416-09. Epub 2010 Jun 16.


Glycogen synthase kinase-3 regulates endoplasmic reticulum (ER) stress-induced CHOP expression in neuronal cells.

Meares GP, Mines MA, Beurel E, Eom TY, Song L, Zmijewska AA, Jope RS.

Exp Cell Res. 2011 Jul 1;317(11):1621-8. doi: 10.1016/j.yexcr.2011.02.012. Epub 2011 Feb 26.


Activation of the UPR protects against cigarette smoke-induced RPE apoptosis through up-regulation of Nrf2.

Huang C, Wang JJ, Ma JH, Jin C, Yu Q, Zhang SX.

J Biol Chem. 2015 Feb 27;290(9):5367-80. doi: 10.1074/jbc.M114.603738. Epub 2015 Jan 7.


Endoplasmic reticulum stress signaling is involved in silver nanoparticles-induced apoptosis.

Zhang R, Piao MJ, Kim KC, Kim AD, Choi JY, Choi J, Hyun JW.

Int J Biochem Cell Biol. 2012 Jan;44(1):224-32. doi: 10.1016/j.biocel.2011.10.019. Epub 2011 Nov 3.


Neuronal apoptosis induced by endoplasmic reticulum stress is regulated by ATF4-CHOP-mediated induction of the Bcl-2 homology 3-only member PUMA.

Galehdar Z, Swan P, Fuerth B, Callaghan SM, Park DS, Cregan SP.

J Neurosci. 2010 Dec 15;30(50):16938-48. doi: 10.1523/JNEUROSCI.1598-10.2010.


Coronavirus infection induces DNA replication stress partly through interaction of its nonstructural protein 13 with the p125 subunit of DNA polymerase δ.

Xu LH, Huang M, Fang SG, Liu DX.

J Biol Chem. 2011 Nov 11;286(45):39546-59. doi: 10.1074/jbc.M111.242206. Epub 2011 Sep 14.


Cytokine-induced beta-cell death is independent of endoplasmic reticulum stress signaling.

Akerfeldt MC, Howes J, Chan JY, Stevens VA, Boubenna N, McGuire HM, King C, Biden TJ, Laybutt DR.

Diabetes. 2008 Nov;57(11):3034-44. doi: 10.2337/db07-1802. Epub 2008 Jun 30.


Gene regulatory network of unfolded protein response genes in endoplasmic reticulum stress.

Takayanagi S, Fukuda R, Takeuchi Y, Tsukada S, Yoshida K.

Cell Stress Chaperones. 2013 Jan;18(1):11-23. doi: 10.1007/s12192-012-0351-5. Epub 2012 Jul 18.


Protein kinase CK2 protects multiple myeloma cells from ER stress-induced apoptosis and from the cytotoxic effect of HSP90 inhibition through regulation of the unfolded protein response.

Manni S, Brancalion A, Tubi LQ, Colpo A, Pavan L, Cabrelle A, Ave E, Zaffino F, Di Maira G, Ruzzene M, Adami F, Zambello R, Pitari MR, Tassone P, Pinna LA, Gurrieri C, Semenzato G, Piazza F.

Clin Cancer Res. 2012 Apr 1;18(7):1888-900. doi: 10.1158/1078-0432.CCR-11-1789. Epub 2012 Feb 20.


Testicular hyperthermia induces Unfolded Protein Response signaling activation in spermatocyte.

Kim JH, Park SJ, Kim TS, Park HJ, Park J, Kim BK, Kim GR, Kim JM, Huang SM, Chae JI, Park CK, Lee DS.

Biochem Biophys Res Commun. 2013 May 17;434(4):861-6. doi: 10.1016/j.bbrc.2013.04.032. Epub 2013 Apr 20.

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