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1.

Association between baseline fetal hemoglobin levels and incidence of severe vaso-occlusive pain episodes in children with sickle cell anemia.

Bhatnagar P, Keefer JR, Casella JF, Barron-Casella EA, Bean CJ, Hooper CW, Payne AB, Arking DE, Debaun MR.

Pediatr Blood Cancer. 2013 Oct;60(10):E125-7. doi: 10.1002/pbc.24588. Epub 2013 May 15.

2.

Effect of hydroxyurea on mortality and morbidity in adult sickle cell anemia: risks and benefits up to 9 years of treatment.

Steinberg MH, Barton F, Castro O, Pegelow CH, Ballas SK, Kutlar A, Orringer E, Bellevue R, Olivieri N, Eckman J, Varma M, Ramirez G, Adler B, Smith W, Carlos T, Ataga K, DeCastro L, Bigelow C, Saunthararajah Y, Telfer M, Vichinsky E, Claster S, Shurin S, Bridges K, Waclawiw M, Bonds D, Terrin M.

JAMA. 2003 Apr 2;289(13):1645-51. Erratum in: JAMA. 2003 Aug 13;290(6):756.

PMID:
12672732
3.

Markers of severe vaso-occlusive painful episode frequency in children and adolescents with sickle cell anemia.

Darbari DS, Onyekwere O, Nouraie M, Minniti CP, Luchtman-Jones L, Rana S, Sable C, Ensing G, Dham N, Campbell A, Arteta M, Gladwin MT, Castro O, Taylor JG 6th, Kato GJ, Gordeuk V.

J Pediatr. 2012 Feb;160(2):286-90. doi: 10.1016/j.jpeds.2011.07.018. Epub 2011 Sep 3.

4.

Hemorheological risk factors of acute chest syndrome and painful vaso-occlusive crisis in children with sickle cell disease.

Lamarre Y, Romana M, Waltz X, Lalanne-Mistrih ML, Tressières B, Divialle-Doumdo L, Hardy-Dessources MD, Vent-Schmidt J, Petras M, Broquere C, Maillard F, Tarer V, Etienne-Julan M, Connes P.

Haematologica. 2012 Nov;97(11):1641-7. doi: 10.3324/haematol.2012.066670. Epub 2012 Jun 11.

5.

The relationship between fetal hemoglobin and disease severity in children with sickle cell anemia.

Odenheimer DJ, Sarnaik SA, Whitten CF, Rucknagel DL, Sing CF.

Am J Med Genet. 1987 Jul;27(3):525-35.

PMID:
2443006
6.

Hydroxyurea therapy in children severely affected with sickle cell disease.

Scott JP, Hillery CA, Brown ER, Misiewicz V, Labotka RJ.

J Pediatr. 1996 Jun;128(6):820-8.

PMID:
8648542
7.

Pain in sickle cell disease. Rates and risk factors.

Platt OS, Thorington BD, Brambilla DJ, Milner PF, Rosse WF, Vichinsky E, Kinney TR.

N Engl J Med. 1991 Jul 4;325(1):11-6.

8.

Level of fetal hemoglobin as an indicator of clinical complications in sickle cell anemia.

Bordin JO, Kerbauy J, Lourenço DM, Sesso R.

Braz J Med Biol Res. 1989;22(11):1347-53.

PMID:
2484125
9.

Predictors of fetal hemoglobin response in children with sickle cell anemia receiving hydroxyurea therapy.

Ware RE, Eggleston B, Redding-Lallinger R, Wang WC, Smith-Whitley K, Daeschner C, Gee B, Styles LA, Helms RW, Kinney TR, Ohene-Frempong K.

Blood. 2002 Jan 1;99(1):10-4.

10.

Impact of chronic transfusion on incidence of pain and acute chest syndrome during the Stroke Prevention Trial (STOP) in sickle-cell anemia.

Miller ST, Wright E, Abboud M, Berman B, Files B, Scher CD, Styles L, Adams RJ; STOP Investigators.

J Pediatr. 2001 Dec;139(6):785-9.

PMID:
11743502
11.

Low fixed-dose hydroxyurea in severely affected Indian children with sickle cell disease.

Jain DL, Sarathi V, Desai S, Bhatnagar M, Lodha A.

Hemoglobin. 2012;36(4):323-32. doi: 10.3109/03630269.2012.697948.

PMID:
22734586
12.

The effect of increased fetal hemoglobin production on the frequency of vaso-occlusive crisis in sickle cell disease.

Dover GJ, Charache S.

Prog Clin Biol Res. 1987;240:277-85. No abstract available.

PMID:
2441416
13.

Delayed hemolytic transfusion reaction/hyperhemolysis syndrome in children with sickle cell disease.

Talano JA, Hillery CA, Gottschall JL, Baylerian DM, Scott JP.

Pediatrics. 2003 Jun;111(6 Pt 1):e661-5.

PMID:
12777582
14.

Fetal hemoglobin and F-cell responses to long-term hydroxyurea treatment in young sickle cell patients. The French Study Group on Sickle Cell Disease.

Maier-Redelsperger M, de Montalembert M, Flahault A, Neonato MG, Ducrocq R, Masson MP, Girot R, Elion J.

Blood. 1998 Jun 15;91(12):4472-9.

15.

DNA polymorphisms at the BCL11A, HBS1L-MYB, and beta-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease.

Lettre G, Sankaran VG, Bezerra MA, Araújo AS, Uda M, Sanna S, Cao A, Schlessinger D, Costa FF, Hirschhorn JN, Orkin SH.

Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11869-74. doi: 10.1073/pnas.0804799105. Epub 2008 Jul 30.

16.

Hydroxyurea in sickle cell disease--a study of clinico-pharmacological efficacy in the Indian haplotype.

Italia K, Jain D, Gattani S, Jijina F, Nadkarni A, Sawant P, Nair S, Mohanty D, Ghosh K, Colah R.

Blood Cells Mol Dis. 2009 Jan-Feb;42(1):25-31. doi: 10.1016/j.bcmd.2008.08.003. Epub 2008 Oct 26.

PMID:
18954999
17.

Clinical and hematologic effects of hydroxyurea in children with sickle cell anemia.

Jayabose S, Tugal O, Sandoval C, Patel P, Puder D, Lin T, Visintainer P.

J Pediatr. 1996 Oct;129(4):559-65.

PMID:
8859263
18.

Vaso-occlusion in children with sickle cell disease: clinical characteristics and biologic correlates.

Dampier C, Setty BN, Eggleston B, Brodecki D, O'neal P, Stuart M.

J Pediatr Hematol Oncol. 2004 Dec;26(12):785-90.

PMID:
15591896
19.

Quantitative analysis of erythrocytes containing fetal hemoglobin (F cells) in children with sickle cell disease.

Marcus SJ, Kinney TR, Schultz WH, O'Branski EE, Ware RE.

Am J Hematol. 1997 Jan;54(1):40-6.

PMID:
8980259
20.

Foetal haemoglobin in homozygous sickle cell disease: a study of patients with low HBF levels.

Donaldson A, Thomas P, Serjeant BE, Serjeant GR.

Clin Lab Haematol. 2001 Oct;23(5):285-9.

PMID:
11703409
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