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Items: 1 to 20 of 93


Prognostic significance of Bcl-xL expression and efficacy of Bcl-xL targeting therapy in urothelial carcinoma.

Yoshimine S, Kikuchi E, Kosaka T, Mikami S, Miyajima A, Okada Y, Oya M.

Br J Cancer. 2013 Jun 11;108(11):2312-20. doi: 10.1038/bjc.2013.216. Epub 2013 May 14.


Prognostic significance of Bcl-xL gene expression in human colorectal cancer.

Jin-Song Y, Zhao-Xia W, Cheng-Yu L, Xiao-Di L, Ming S, Yuan-Yuan G, Wei D.

Acta Histochem. 2011 Dec;113(8):810-4. doi: 10.1016/j.acthis.2011.01.002. Epub 2011 Jan 28.


Targeting Bcl-2/Bcl-XL induces antitumor activity in uveal melanoma patient-derived xenografts.

Némati F, de Montrion C, Lang G, Kraus-Berthier L, Carita G, Sastre-Garau X, Berniard A, Vallerand D, Geneste O, de Plater L, Pierré A, Lockhart B, Desjardins L, Piperno-Neumann S, Depil S, Decaudin D.

PLoS One. 2014 Jan 13;9(1):e80836. doi: 10.1371/journal.pone.0080836. eCollection 2014.


Adenovirus-mediated siRNA targeting Bcl-xL inhibits proliferation, reduces invasion and enhances radiosensitivity of human colorectal cancer cells.

Yang J, Sun M, Zhang A, Lv C, De W, Wang Z.

World J Surg Oncol. 2011 Oct 4;9:117. doi: 10.1186/1477-7819-9-117.


Chemosensitization of solid tumors by inhibition of Bcl-xL expression using DNAzyme.

Yu X, Yang L, Cairns MJ, Dass C, Saravolac E, Li X, Sun LQ.

Oncotarget. 2014 Oct 15;5(19):9039-48.


Clinical significance of L-type amino acid transporter 1 expression as a prognostic marker and potential of new targeting therapy in biliary tract cancer.

Kaira K, Sunose Y, Ohshima Y, Ishioka NS, Arakawa K, Ogawa T, Sunaga N, Shimizu K, Tominaga H, Oriuchi N, Itoh H, Nagamori S, Kanai Y, Yamaguchi A, Segawa A, Ide M, Mori M, Oyama T, Takeyoshi I.

BMC Cancer. 2013 Oct 16;13:482. doi: 10.1186/1471-2407-13-482.


Prognostic significance of 5-fluorouracil metabolism-relating enzymes and enhanced chemosensitivity to 5-fluorouracil by 5-chloro 2,4-dihydroxy-pyridine in urothelial carcinoma.

Ide H, Kikuchi E, Hasegawa M, Kozakai N, Kosaka T, Miyajima A, Oya M.

BMC Cancer. 2012 Sep 22;12:420. doi: 10.1186/1471-2407-12-420.


Role of Bcl-xL/Beclin-1 in interplay between apoptosis and autophagy in oxaliplatin and bortezomib-induced cell death.

Kim SY, Song X, Zhang L, Bartlett DL, Lee YJ.

Biochem Pharmacol. 2014 Mar 15;88(2):178-88. doi: 10.1016/j.bcp.2014.01.027. Epub 2014 Jan 31.


The novel BH3 α-helix mimetic JY-1-106 induces apoptosis in a subset of cancer cells (lung cancer, colon cancer and mesothelioma) by disrupting Bcl-xL and Mcl-1 protein-protein interactions with Bak.

Cao X, Yap JL, Newell-Rogers MK, Peddaboina C, Jiang W, Papaconstantinou HT, Jupitor D, Rai A, Jung KY, Tubin RP, Yu W, Vanommeslaeghe K, Wilder PT, MacKerell AD Jr, Fletcher S, Smythe RW.

Mol Cancer. 2013 May 16;12(1):42. doi: 10.1186/1476-4598-12-42.


Moderate activation of the apoptosis inhibitor bcl-xL worsens the prognosis in pancreatic cancer.

Friess H, Lu Z, Andrén-Sandberg A, Berberat P, Zimmermann A, Adler G, Schmid R, Büchler MW.

Ann Surg. 1998 Dec;228(6):780-7.


Bcl-XL antisense oligonucleotides coupled with antennapedia enhances radiation-induced apoptosis in pancreatic cancer.

Masui T, Hosotani R, Ito D, Kami K, Koizumi M, Mori T, Toyoda E, Nakajima S, Miyamoto Y, Fujimoto K, Doi R.

Surgery. 2006 Aug;140(2):149-60.


Prognostic value of apoptosis-related markers in urothelial cancer of the upper urinary tract.

Jeong IG, Kim SH, Jeon HG, Kim BH, Moon KC, Lee SE, Lee E.

Hum Pathol. 2009 May;40(5):668-77. doi: 10.1016/j.humpath.2008.10.010. Epub 2009 Jan 20.


Suppressing the growth of rectal cancer xenografts derived from patient tumors by an adenovector expressing small hairpin RNA targeting Bcl-XL.

Zhu H, Zhou W, Hu J, Huang Z, Lao W, Huang X, He C.

J Gene Med. 2012 Dec;14(12):761-8. doi: 10.1002/jgm.2681.


Combined targeted inhibition of bcl-2, bcl-XL, epidermal growth factor receptor, and protein kinase A type I causes potent antitumor, apoptotic, and antiangiogenic activity.

Tortora G, Caputo R, Damiano V, Caputo R, Troiani T, Veneziani BM, De Placido S, Bianco AR, Zangemeister-Wittke U, Ciardiello F.

Clin Cancer Res. 2003 Feb;9(2):866-71.


Induction of apoptosis and antitumor effects of a small molecule inhibitor of Bcl-2 and Bcl-xl, gossypol acetate, in multiple myeloma in vitro and in vivo.

Lin J, Wu Y, Yang D, Zhao Y.

Oncol Rep. 2013 Aug;30(2):731-8. doi: 10.3892/or.2013.2489. Epub 2013 May 23.


Prognostic value of plasma fibrinogen levels in patients with localized upper tract urothelial carcinoma.

Tanaka N, Kikuchi E, Matsumoto K, Hayakawa N, Ide H, Miyajima A, Nakamura S, Oya M.

BJU Int. 2013 May;111(6):857-64. doi: 10.1111/j.1464-410X.2012.11353.x. Epub 2012 Jul 3.


Prognostic significance of Bcl-xL in human hepatocellular carcinoma.

Watanabe J, Kushihata F, Honda K, Sugita A, Tateishi N, Mominoki K, Matsuda S, Kobayashi N.

Surgery. 2004 Jun;135(6):604-12.


Effect of antiviral therapy on the immunohistochemical expression of bcl-xL and bax protein in patients with HBeAg-negative chronic hepatitis B.

Cholongitas E, Papatheodoridis GV, Manesis EK, Petraki K, Tiniakos D, Hadziyannis SJ.

J Med Virol. 2011 Jul;83(7):1165-71. doi: 10.1002/jmv.21780.


Decreased expression of Beclin 1 correlates closely with Bcl-xL expression and poor prognosis of ovarian carcinoma.

Lin HX, Qiu HJ, Zeng F, Rao HL, Yang GF, Kung HF, Zhu XF, Zeng YX, Cai MY, Xie D.

PLoS One. 2013;8(4):e60516. doi: 10.1371/journal.pone.0060516. Epub 2013 Apr 3.

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