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Acute hematological effects of solar particle event proton radiation in the porcine model.

Sanzari JK, Wan XS, Wroe AJ, Rightnar S, Cengel KA, Diffenderfer ES, Krigsfeld GS, Gridley DS, Kennedy AR.

Radiat Res. 2013 Jul;180(1):7-16. doi: 10.1667/RR3027.1. Epub 2013 May 14.


Relative biological effectiveness of simulated solar particle event proton radiation to induce acute hematological change in the porcine model.

Sanzari JK, Wan SX, Diffenderfer ES, Cengel KA, Kennedy AR.

J Radiat Res. 2014 Mar 1;55(2):228-44. doi: 10.1093/jrr/rrt108. Epub 2013 Sep 11.


Acute biological effects of simulating the whole-body radiation dose distribution from a solar particle event using a porcine model.

Wilson JM, Sanzari JK, Diffenderfer ES, Yee SS, Seykora JT, Maks C, Ware JH, Litt HI, Reetz JA, McDonough J, Weissman D, Kennedy AR, Cengel KA.

Radiat Res. 2011 Nov;176(5):649-59. Epub 2011 Aug 22.


Variable hematopoietic responses to acute photons, protons and simulated solar particle event protons.

Gridley DS, Rizvi A, Luo-Owen X, Makinde AY, Coutrakon GB, Koss P, Slater JM, Pecaut MJ.

In Vivo. 2008 Mar-Apr;22(2):159-69.


Low-dose photon and simulated solar particle event proton effects on Foxp3+ T regulatory cells and other leukocytes.

Gridley DS, Luo-Owen X, Rizvi A, Makinde A, Pecaut M, Mao XW, Slater JM.

Technol Cancer Res Treat. 2010 Dec;9(6):637-49.


Analysis of white blood cell counts in mice after gamma- or proton-radiation exposure.

Maks CJ, Wan XS, Ware JH, Romero-Weaver AL, Sanzari JK, Wilson JM, Rightnar S, Wroe AJ, Koss P, Gridley DS, Slater JM, Kennedy AR.

Radiat Res. 2011 Aug;176(2):170-6. doi: 10.1667/RR2413.1. Epub 2011 Apr 8.


The Effects of Gamma and Proton Radiation Exposure on Hematopoietic Cell Counts in the Ferret Model.

Sanzari JK, Wan XS, Krigsfeld GS, Wroe AJ, Gridley DS, Kennedy AR.

Gravit Space Res. 2013 Oct;1(1):79-94.


Hematological changes as prognostic indicators of survival: similarities between Gottingen minipigs, humans, and other large animal models.

Moroni M, Lombardini E, Salber R, Kazemzedeh M, Nagy V, Olsen C, Whitnall MH.

PLoS One. 2011;6(9):e25210. doi: 10.1371/journal.pone.0025210. Epub 2011 Sep 28.


Leukocyte activity is altered in a ground based murine model of microgravity and proton radiation exposure.

Sanzari JK, Romero-Weaver AL, James G, Krigsfeld G, Lin L, Diffenderfer ES, Kennedy AR.

PLoS One. 2013 Aug 14;8(8):e71757. doi: 10.1371/journal.pone.0071757. eCollection 2013.


Using electron beam radiation to simulate the dose distribution for whole body solar particle event proton exposure.

Cengel KA, Diffenderfer ES, Avery S, Kennedy AR, McDonough J.

Radiat Environ Biophys. 2010 Nov;49(4):715-21. doi: 10.1007/s00411-010-0315-z. Epub 2010 Aug 20.


The Gottingen minipig is a model of the hematopoietic acute radiation syndrome: G-colony stimulating factor stimulates hematopoiesis and enhances survival from lethal total-body γ-irradiation.

Moroni M, Ngudiankama BF, Christensen C, Olsen CH, Owens R, Lombardini ED, Holt RK, Whitnall MH.

Int J Radiat Oncol Biol Phys. 2013 Aug 1;86(5):986-92. doi: 10.1016/j.ijrobp.2013.04.041.


Kinetics of neutrophils in mice exposed to radiation and/or granulocyte colony-stimulating factor treatment.

Romero-Weaver AL, Wan XS, Diffenderfer ES, Lin L, Kennedy AR.

Radiat Res. 2013 Aug;180(2):177-88. doi: 10.1667/RR3055.1. Epub 2013 Jul 5.


Effect of SPE-like proton or photon radiation on the kinetics of mouse peripheral blood cells and radiation biological effectiveness determinations.

Romero-Weaver AL, Wan XS, Diffenderfer ES, Lin L, Kennedy AR.

Astrobiology. 2013 Jun;13(6):570-7. doi: 10.1089/ast.2012.0916.


Effects of Solar Particle Event-Like Proton Radiation and/or Simulated Microgravity on Circulating Mouse Blood Cells.

Romero-Weaver AL, Lin L, Carabe-Fernandez A, Kennedy AR.

Gravit Space Res. 2014 Aug;2(1):42-53.


Low-dose γ-rays modify CD4(+) T cell signalling response to simulated solar particle event protons in a mouse model.

Rizvi A, Pecaut MJ, Slater JM, Subramaniam S, Gridley DS.

Int J Radiat Biol. 2011 Jan;87(1):24-35. doi: 10.3109/09553002.2010.518206.


Dermatopathology effects of simulated solar particle event radiation exposure in the porcine model.

Sanzari JK, Diffenderfer ES, Hagan S, Billings PC, Gridley DS, Seykora JT, Kennedy AR, Cengel KA.

Life Sci Space Res (Amst). 2015 Jul;6:21-8. doi: 10.1016/j.lssr.2015.06.003. Epub 2015 Jun 18.


Accelerated hematopoietic syndrome after radiation doses bridging hematopoietic (H-ARS) and gastrointestinal (GI-ARS) acute radiation syndrome: early hematological changes and systemic inflammatory response syndrome in minipig.

Moroni M, Elliott TB, Deutz NE, Olsen CH, Owens R, Christensen C, Lombardini ED, Whitnall MH.

Int J Radiat Biol. 2014 May;90(5):363-72. doi: 10.3109/09553002.2014.892226.

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