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Items: 1 to 20 of 107

1.
2.

Structural basis for the association of the redox-sensitive target of rapamycin FATC domain with membrane-mimetic micelles.

Dames SA.

J Biol Chem. 2010 Mar 5;285(10):7766-75. doi: 10.1074/jbc.M109.058404. Epub 2009 Dec 30.

3.

Characterization of the immersion properties of the peripheral membrane anchor of the FATC domain of the kinase "target of rapamycin" by NMR, oriented CD spectroscopy, and MD simulations.

Sommer LA, Janke JJ, Bennett WF, Bürck J, Ulrich AS, Tieleman DP, Dames SA.

J Phys Chem B. 2014 May 8;118(18):4817-31. doi: 10.1021/jp501533d. Epub 2014 Apr 25.

PMID:
24725177
4.
5.

Emerging common themes in regulation of PIKKs and PI3Ks.

Lempiäinen H, Halazonetis TD.

EMBO J. 2009 Oct 21;28(20):3067-73. doi: 10.1038/emboj.2009.281. Epub 2009 Sep 24. Review.

6.

The FATC domains of PIKK proteins are functionally equivalent and participate in the Tip60-dependent activation of DNA-PKcs and ATM.

Jiang X, Sun Y, Chen S, Roy K, Price BD.

J Biol Chem. 2006 Jun 9;281(23):15741-6. Epub 2006 Apr 9.

7.

The solution structure of the FATC domain of the protein kinase target of rapamycin suggests a role for redox-dependent structural and cellular stability.

Dames SA, Mulet JM, Rathgeb-Szabo K, Hall MN, Grzesiek S.

J Biol Chem. 2005 May 27;280(21):20558-64. Epub 2005 Mar 16.

8.

The FKBP-rapamycin binding domain of human TOR undergoes strong conformational changes in the presence of membrane mimetics with and without the regulator phosphatidic acid.

Rodriguez Camargo DC, Link NM, Dames SA.

Biochemistry. 2012 Jun 19;51(24):4909-21. doi: 10.1021/bi3002133. Epub 2012 Jun 5.

PMID:
22620485
9.

Distant N- and C-terminal domains are required for intrinsic kinase activity of SMG-1, a critical component of nonsense-mediated mRNA decay.

Morita T, Yamashita A, Kashima I, Ogata K, Ishiura S, Ohno S.

J Biol Chem. 2007 Mar 16;282(11):7799-808. Epub 2007 Jan 17.

10.

Three-dimensional structure and regulation of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs).

Rivera-Calzada A, Maman JD, Spagnolo L, Pearl LH, Llorca O.

Structure. 2005 Feb;13(2):243-55. Erratum in: Structure (Camb). 2005 Mar;13(3):495. Maman, Joseph P [corrected to Maman, Joseph D].

11.
12.

Regulation of the Target of Rapamycin and Other Phosphatidylinositol 3-Kinase-Related Kinases by Membrane Targeting.

De Cicco M, Rahim MS, Dames SA.

Membranes (Basel). 2015 Sep 29;5(4):553-75. doi: 10.3390/membranes5040553. Review.

13.

PIKKs--the solenoid nest where partners and kinases meet.

Baretić D, Williams RL.

Curr Opin Struct Biol. 2014 Dec;29:134-42. doi: 10.1016/j.sbi.2014.11.003. Epub 2014 Dec 3. Review.

PMID:
25460276
14.

Structure and dynamics of micelle-bound neuropeptide Y: comparison with unligated NPY and implications for receptor selection.

Bader R, Bettio A, Beck-Sickinger AG, Zerbe O.

J Mol Biol. 2001 Jan 12;305(2):307-29.

PMID:
11124908
15.

NMR structural studies of the Ste11 SAM domain in the dodecyl phosphocholine micelle.

Bhunia A, Domadia PN, Mohanram H, Bhattacharjya S.

Proteins. 2009 Feb 1;74(2):328-43. doi: 10.1002/prot.22166.

PMID:
18618697
16.

Structure, dynamics, lipid binding, and physiological relevance of the putative GTPase-binding domain of Dictyostelium formin C.

Dames SA, Junemann A, Sass HJ, Schönichen A, Stopschinski BE, Grzesiek S, Faix J, Geyer M.

J Biol Chem. 2011 Oct 21;286(42):36907-20. doi: 10.1074/jbc.M111.225052. Epub 2011 Aug 16.

17.

Interaction of a peptide derived from C-terminus of human TRPA1 channel with model membranes mimicking the inner leaflet of the plasma membrane.

Witschas K, Jobin ML, Korkut DN, Vladan MM, Salgado G, Lecomte S, Vlachova V, Alves ID.

Biochim Biophys Acta. 2015 May;1848(5):1147-56. doi: 10.1016/j.bbamem.2015.02.003. Epub 2015 Feb 14.

18.

Contributions of the N- and C-terminal helical segments to the lipid-free structure and lipid interaction of apolipoprotein A-I.

Tanaka M, Dhanasekaran P, Nguyen D, Ohta S, Lund-Katz S, Phillips MC, Saito H.

Biochemistry. 2006 Aug 29;45(34):10351-8.

PMID:
16922511
20.
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