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C/EBP maintains chromatin accessibility in liver and facilitates glucocorticoid receptor recruitment to steroid response elements.

Grøntved L, John S, Baek S, Liu Y, Buckley JR, Vinson C, Aguilera G, Hager GL.

EMBO J. 2013 May 29;32(11):1568-83. doi: 10.1038/emboj.2013.106. Epub 2013 May 10.


Glucocorticoid receptor is involved in the breed-dependent transcriptional regulation of 3β-hydroxysteroid dehydrogenase in the liver of preweaning piglets.

Li X, Jia Y, Li R, Sun Z, Li X, Sui S, Zhao R.

BMC Vet Res. 2015 May 26;11:123. doi: 10.1186/s12917-015-0441-6.


Genomic redistribution of GR monomers and dimers mediates transcriptional response to exogenous glucocorticoid in vivo.

Lim HW, Uhlenhaut NH, Rauch A, Weiner J, Hübner S, Hübner N, Won KJ, Lazar MA, Tuckermann J, Steger DJ.

Genome Res. 2015 Jun;25(6):836-44. doi: 10.1101/gr.188581.114. Epub 2015 May 8.


Transcriptional activation by the thyroid hormone receptor through ligand-dependent receptor recruitment and chromatin remodelling.

Grøntved L, Waterfall JJ, Kim DW, Baek S, Sung MH, Zhao L, Park JW, Nielsen R, Walker RL, Zhu YJ, Meltzer PS, Hager GL, Cheng SY.

Nat Commun. 2015 Apr 28;6:7048. doi: 10.1038/ncomms8048.


Selective coregulator function and restriction of steroid receptor chromatin occupancy by Hic-5.

Chodankar R, Wu DY, Gerke DS, Stallcup MR.

Mol Endocrinol. 2015 May;29(5):716-29. doi: 10.1210/me.2014-1403. Epub 2015 Mar 12.


Dynamics of chromatin accessibility and long-range interactions in response to glucocorticoid pulsing.

Stavreva DA, Coulon A, Baek S, Sung MH, John S, Stixova L, Tesikova M, Hakim O, Miranda T, Hawkins M, Stamatoyannopoulos JA, Chow CC, Hager GL.

Genome Res. 2015 Jun;25(6):845-57. doi: 10.1101/gr.184168.114. Epub 2015 Feb 12.


Distinct, genome-wide, gene-specific selectivity patterns of four glucocorticoid receptor coregulators.

Wu DY, Ou CY, Chodankar R, Siegmund KD, Stallcup MR.

Nucl Recept Signal. 2014 Nov 4;12:e002. doi: 10.1621/nrs.12002. eCollection 2014.


Inhibition of corticosteroid-binding globulin gene expression by glucocorticoids involves C/EBPβ.

Verhoog N, Allie-Reid F, Vanden Berghe W, Smith C, Haegeman G, Hapgood J, Louw A.

PLoS One. 2014 Oct 21;9(10):e110702. doi: 10.1371/journal.pone.0110702. eCollection 2014.


Dynamic GATA4 enhancers shape the chromatin landscape central to heart development and disease.

He A, Gu F, Hu Y, Ma Q, Ye LY, Akiyama JA, Visel A, Pennacchio LA, Pu WT.

Nat Commun. 2014 Sep 24;5:4907. doi: 10.1038/ncomms5907.


Medroxyprogesterone acetate differentially regulates interleukin (IL)-12 and IL-10 in a human ectocervical epithelial cell line in a glucocorticoid receptor (GR)-dependent manner.

Louw-du Toit R, Hapgood JP, Africander D.

J Biol Chem. 2014 Nov 7;289(45):31136-49. doi: 10.1074/jbc.M114.587311. Epub 2014 Sep 8.


Distinctly different dynamics and kinetics of two steroid receptors at the same response elements in living cells.

Nenseth HZ, Dezitter X, Tesikova M, Mueller F, Klokk TI, Hager GL, Saatcioglu F.

PLoS One. 2014 Aug 18;9(8):e105204. doi: 10.1371/journal.pone.0105204. eCollection 2014.


Glucocorticoid receptor coordinates transcription factor-dominated regulatory network in macrophages.

Chinenov Y, Coppo M, Gupte R, Sacta MA, Rogatsky I.

BMC Genomics. 2014 Aug 6;15:656. doi: 10.1186/1471-2164-15-656.


Glucocorticoid receptor binds half sites as a monomer and regulates specific target genes.

Schiller BJ, Chodankar R, Watson LC, Stallcup MR, Yamamoto KR.

Genome Biol. 2014 Jul 31;15(7):418. doi: 10.1186/s13059-014-0418-y.


Single-molecule analysis of transcription factor binding at transcription sites in live cells.

Morisaki T, Müller WG, Golob N, Mazza D, McNally JG.

Nat Commun. 2014 Jul 18;5:4456. doi: 10.1038/ncomms5456.


Open chromatin profiling in mice livers reveals unique chromatin variations induced by high fat diet.

Leung A, Parks BW, Du J, Trac C, Setten R, Chen Y, Brown K, Lusis AJ, Natarajan R, Schones DE.

J Biol Chem. 2014 Aug 22;289(34):23557-67. doi: 10.1074/jbc.M114.581439. Epub 2014 Jul 8.


Microbiota modulate transcription in the intestinal epithelium without remodeling the accessible chromatin landscape.

Camp JG, Frank CL, Lickwar CR, Guturu H, Rube T, Wenger AM, Chen J, Bejerano G, Crawford GE, Rawls JF.

Genome Res. 2014 Sep;24(9):1504-16. doi: 10.1101/gr.165845.113. Epub 2014 Jun 24.


Coregulator cell cycle and apoptosis regulator 1 (CCAR1) positively regulates adipocyte differentiation through the glucocorticoid signaling pathway.

Ou CY, Chen TC, Lee JV, Wang JC, Stallcup MR.

J Biol Chem. 2014 Jun 13;289(24):17078-86. doi: 10.1074/jbc.M114.548081. Epub 2014 May 8.


A living biosensor model to dynamically trace glucocorticoid transcriptional activity during development and adult life in zebrafish.

Benato F, Colletti E, Skobo T, Moro E, Colombo L, Argenton F, Dalla Valle L.

Mol Cell Endocrinol. 2014 Jul 5;392(1-2):60-72. doi: 10.1016/j.mce.2014.04.015. Epub 2014 May 4.


Caveolin-1 regulates genomic action of the glucocorticoid receptor in neural stem cells.

Peffer ME, Chandran UR, Luthra S, Volonte D, Galbiati F, Garabedian MJ, Monaghan AP, DeFranco DB.

Mol Cell Biol. 2014 Jul;34(14):2611-23.


Structures and mechanism for the design of highly potent glucocorticoids.

He Y, Yi W, Suino-Powell K, Zhou XE, Tolbert WD, Tang X, Yang J, Yang H, Shi J, Hou L, Jiang H, Melcher K, Xu HE.

Cell Res. 2014 Jun;24(6):713-26. doi: 10.1038/cr.2014.52. Epub 2014 Apr 25.

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