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Results: 1 to 20 of 135

1.

Spdef null mice lack conjunctival goblet cells and provide a model of dry eye.

Marko CK, Menon BB, Chen G, Whitsett JA, Clevers H, Gipson IK.

Am J Pathol. 2013 Jul;183(1):35-48. doi: 10.1016/j.ajpath.2013.03.017. Epub 2013 May 10.

PMID:
23665202
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The ocular surface phenotype of Muc5ac and Muc5b null mice.

Marko CK, Tisdale AS, Spurr-Michaud S, Evans C, Gipson IK.

Invest Ophthalmol Vis Sci. 2014 Jan 15;55(1):291-300. doi: 10.1167/iovs.13-13194.

PMID:
24327612
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

The ets-domain transcription factor Spdef promotes maturation of goblet and paneth cells in the intestinal epithelium.

Gregorieff A, Stange DE, Kujala P, Begthel H, van den Born M, Korving J, Peters PJ, Clevers H.

Gastroenterology. 2009 Oct;137(4):1333-45.e1-3. doi: 10.1053/j.gastro.2009.06.044. Epub 2009 Jun 21.

PMID:
19549527
[PubMed - indexed for MEDLINE]
4.

Entrapment of conjunctival goblet cells by desiccation-induced cornification.

Corrales RM, de Paiva CS, Li DQ, Farley WJ, Henriksson JT, Bergmanson JP, Pflugfelder SC.

Invest Ophthalmol Vis Sci. 2011 Jun 1;52(6):3492-9. doi: 10.1167/iovs.10-5782.

PMID:
21421863
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Topical interferon-gamma neutralization prevents conjunctival goblet cell loss in experimental murine dry eye.

Zhang X, De Paiva CS, Su Z, Volpe EA, Li DQ, Pflugfelder SC.

Exp Eye Res. 2014 Jan;118:117-24. doi: 10.1016/j.exer.2013.11.011. Epub 2013 Dec 4.

PMID:
24315969
[PubMed - indexed for MEDLINE]
6.

Time course of ocular surface and lacrimal gland changes in a new scopolamine-induced dry eye model.

Viau S, Maire MA, Pasquis B, Grégoire S, Fourgeux C, Acar N, Bretillon L, Creuzot-Garcher CP, Joffre C.

Graefes Arch Clin Exp Ophthalmol. 2008 Jun;246(6):857-67. doi: 10.1007/s00417-008-0784-9. Epub 2008 Mar 21.

PMID:
18357464
[PubMed - indexed for MEDLINE]
7.

Altered cytokine balance in the tear fluid and conjunctiva of patients with Sjögren's syndrome keratoconjunctivitis sicca.

Pflugfelder SC, Jones D, Ji Z, Afonso A, Monroy D.

Curr Eye Res. 1999 Sep;19(3):201-11.

PMID:
10487957
[PubMed - indexed for MEDLINE]
8.

Interferon-γ exacerbates dry eye-induced apoptosis in conjunctiva through dual apoptotic pathways.

Zhang X, Chen W, De Paiva CS, Corrales RM, Volpe EA, McClellan AJ, Farley WJ, Li DQ, Pflugfelder SC.

Invest Ophthalmol Vis Sci. 2011 Aug 9;52(9):6279-85. doi: 10.1167/iovs.10-7081.

PMID:
21474767
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus production.

Chen G, Korfhagen TR, Xu Y, Kitzmiller J, Wert SE, Maeda Y, Gregorieff A, Clevers H, Whitsett JA.

J Clin Invest. 2009 Oct;119(10):2914-24. doi: 10.1172/JCI39731. Epub 2009 Sep 14.

PMID:
19759516
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Goblet cell numbers and epithelial proliferation in the conjunctiva of patients with dry eye syndrome treated with cyclosporine.

Kunert KS, Tisdale AS, Gipson IK.

Arch Ophthalmol. 2002 Mar;120(3):330-7. Erratum in: Arch Ophthalmol 2002 Aug;120(8):1099.

PMID:
11879137
[PubMed - indexed for MEDLINE]
11.

Immune profile of squamous metaplasia development in autoimmune regulator-deficient dry eye.

Chen YT, Li S, Nikulina K, Porco T, Gallup M, McNamara N.

Mol Vis. 2009;15:563-76. Epub 2009 Mar 23.

PMID:
19365590
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Decreased levels of the goblet cell mucin MUC5AC in tears of patients with Sjögren syndrome.

Argüeso P, Balaram M, Spurr-Michaud S, Keutmann HT, Dana MR, Gipson IK.

Invest Ophthalmol Vis Sci. 2002 Apr;43(4):1004-11.

PMID:
11923240
[PubMed - indexed for MEDLINE]
Free Article
13.

In vitro evidence of nerve growth factor effects on human conjunctival epithelial cell differentiation and mucin gene expression.

Lambiase A, Micera A, Pellegrini G, Merlo D, Rama P, De Luca M, Bonini S, Bonini S.

Invest Ophthalmol Vis Sci. 2009 Oct;50(10):4622-30. doi: 10.1167/iovs.08-2716. Epub 2009 Apr 30.

PMID:
19407015
[PubMed - indexed for MEDLINE]
Free Article
14.

SAM pointed domain ETS factor (SPDEF) regulates terminal differentiation and maturation of intestinal goblet cells.

Noah TK, Kazanjian A, Whitsett J, Shroyer NF.

Exp Cell Res. 2010 Feb 1;316(3):452-65. doi: 10.1016/j.yexcr.2009.09.020. Epub 2009 Sep 26.

PMID:
19786015
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Morphologic alterations of the palpebral conjunctival epithelium in a dry eye model.

Henriksson JT, De Paiva CS, Farley W, Pflugfelder SC, Burns AR, Bergmanson JP.

Cornea. 2013 Apr;32(4):483-90. doi: 10.1097/ICO.0b013e318265682c.

PMID:
23146932
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Correlation of goblet cell density and mucosal epithelial membrane mucin expression with rose bengal staining in patients with ocular irritation.

Pflugfelder SC, Tseng SC, Yoshino K, Monroy D, Felix C, Reis BL.

Ophthalmology. 1997 Feb;104(2):223-35.

PMID:
9052626
[PubMed - indexed for MEDLINE]
17.

Interleukin-1 receptor-1-deficient mice show attenuated production of ocular surface inflammatory cytokines in experimental dry eye.

Narayanan S, Corrales RM, Farley W, McDermott AM, Pflugfelder SC.

Cornea. 2008 Aug;27(7):811-7. doi: 10.1097/ICO.0b013e31816bf46c.

PMID:
18650668
[PubMed - indexed for MEDLINE]
18.

Dry eye-induced conjunctival epithelial squamous metaplasia is modulated by interferon-gamma.

De Paiva CS, Villarreal AL, Corrales RM, Rahman HT, Chang VY, Farley WJ, Stern ME, Niederkorn JY, Li DQ, Pflugfelder SC.

Invest Ophthalmol Vis Sci. 2007 Jun;48(6):2553-60.

PMID:
17525184
[PubMed - indexed for MEDLINE]
Free Article
19.

Expression of human beta-defensins in conjunctival epithelium: relevance to dry eye disease.

Narayanan S, Miller WL, McDermott AM.

Invest Ophthalmol Vis Sci. 2003 Sep;44(9):3795-801.

PMID:
12939294
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Mucin gene expression in immortalized human corneal-limbal and conjunctival epithelial cell lines.

Gipson IK, Spurr-Michaud S, Argüeso P, Tisdale A, Ng TF, Russo CL.

Invest Ophthalmol Vis Sci. 2003 Jun;44(6):2496-506.

PMID:
12766048
[PubMed - indexed for MEDLINE]
Free Article

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