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Results: 1 to 20 of 119

Similar articles for PubMed (Select 23665168)

1.

Structures of Down syndrome kinases, DYRKs, reveal mechanisms of kinase activation and substrate recognition.

Soundararajan M, Roos AK, Savitsky P, Filippakopoulos P, Kettenbach AN, Olsen JV, Gerber SA, Eswaran J, Knapp S, Elkins JM.

Structure. 2013 Jun 4;21(6):986-96. doi: 10.1016/j.str.2013.03.012. Epub 2013 May 9.

2.

Mechanism of dual specificity kinase activity of DYRK1A.

Walte A, Rüben K, Birner-Gruenberger R, Preisinger C, Bamberg-Lemper S, Hilz N, Bracher F, Becker W.

FEBS J. 2013 Sep;280(18):4495-511. doi: 10.1111/febs.12411. Epub 2013 Jul 22.

PMID:
23809146
3.

Characterization of a domain that transiently converts class 2 DYRKs into intramolecular tyrosine kinases.

Kinstrie R, Luebbering N, Miranda-Saavedra D, Sibbet G, Han J, Lochhead PA, Cleghon V.

Sci Signal. 2010 Mar 2;3(111):ra16. doi: 10.1126/scisignal.2000579.

4.

Deep evolutionary conservation of an intramolecular protein kinase activation mechanism.

Han J, Miranda-Saavedra D, Luebbering N, Singh A, Sibbet G, Ferguson MA, Cleghon V.

PLoS One. 2012;7(1):e29702. doi: 10.1371/journal.pone.0029702. Epub 2012 Jan 3.

5.

Structural and functional characteristics of Dyrk, a novel subfamily of protein kinases with dual specificity.

Becker W, Joost HG.

Prog Nucleic Acid Res Mol Biol. 1999;62:1-17. Review.

PMID:
9932450
6.

dDYRK2: a novel dual-specificity tyrosine-phosphorylation-regulated kinase in Drosophila.

Lochhead PA, Sibbet G, Kinstrie R, Cleghon T, Rylatt M, Morrison DK, Cleghon V.

Biochem J. 2003 Sep 1;374(Pt 2):381-91.

7.

Dual-specificity tyrosine phosphorylation-regulated kinase 1A does not require tyrosine phosphorylation for activity in vitro.

Adayev T, Chen-Hwang MC, Murakami N, Lee E, Bolton DC, Hwang YW.

Biochemistry. 2007 Jun 26;46(25):7614-24. Epub 2007 May 31.

PMID:
17536841
8.

Splice variants of the dual specificity tyrosine phosphorylation-regulated kinase 4 (DYRK4) differ in their subcellular localization and catalytic activity.

Papadopoulos C, Arato K, Lilienthal E, Zerweck J, Schutkowski M, Chatain N, Müller-Newen G, Becker W, de la Luna S.

J Biol Chem. 2011 Feb 18;286(7):5494-505. doi: 10.1074/jbc.M110.157909. Epub 2010 Dec 2.

9.

Specificity determinants of substrate recognition by the protein kinase DYRK1A.

Himpel S, Tegge W, Frank R, Leder S, Joost HG, Becker W.

J Biol Chem. 2000 Jan 28;275(4):2431-8.

10.

Unusual function of the activation loop in the protein kinase DYRK1A.

Wiechmann S, Czajkowska H, de Graaf K, Grötzinger J, Joost HG, Becker W.

Biochem Biophys Res Commun. 2003 Mar 7;302(2):403-8.

PMID:
12604362
11.
12.

DYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1.

Guo X, Williams JG, Schug TT, Li X.

J Biol Chem. 2010 Apr 23;285(17):13223-32. doi: 10.1074/jbc.M110.102574. Epub 2010 Feb 18.

13.

Unveiling the novel dual specificity protein kinases in Bacillus anthracis: identification of the first prokaryotic dual specificity tyrosine phosphorylation-regulated kinase (DYRK)-like kinase.

Arora G, Sajid A, Arulanandh MD, Singhal A, Mattoo AR, Pomerantsev AP, Leppla SH, Maiti S, Singh Y.

J Biol Chem. 2012 Aug 3;287(32):26749-63. doi: 10.1074/jbc.M112.351304. Epub 2012 Jun 18.

14.

DYRK1A autophosphorylation on serine residue 520 modulates its kinase activity via 14-3-3 binding.

Alvarez M, Altafaj X, Aranda S, de la Luna S.

Mol Biol Cell. 2007 Apr;18(4):1167-78. Epub 2007 Jan 17.

15.

Activation-loop autophosphorylation is mediated by a novel transitional intermediate form of DYRKs.

Lochhead PA, Sibbet G, Morrice N, Cleghon V.

Cell. 2005 Jun 17;121(6):925-36.

16.

Identification of the autophosphorylation sites and characterization of their effects in the protein kinase DYRK1A.

Himpel S, Panzer P, Eirmbter K, Czajkowska H, Sayed M, Packman LC, Blundell T, Kentrup H, Grötzinger J, Joost HG, Becker W.

Biochem J. 2001 Nov 1;359(Pt 3):497-505.

17.

Phosphorylation of Ser640 in muscle glycogen synthase by DYRK family protein kinases.

Skurat AV, Dietrich AD.

J Biol Chem. 2004 Jan 23;279(4):2490-8. Epub 2003 Oct 30.

19.

Plasmodium falciparum possesses a unique dual-specificity serine/threonine and tyrosine kinase, Pfnek3.

Low H, Chua CS, Sim TS.

Cell Mol Life Sci. 2012 May;69(9):1523-35. doi: 10.1007/s00018-011-0888-y. Epub 2011 Nov 25.

PMID:
22116321
20.

Harmine specifically inhibits protein kinase DYRK1A and interferes with neurite formation.

Göckler N, Jofre G, Papadopoulos C, Soppa U, Tejedor FJ, Becker W.

FEBS J. 2009 Nov;276(21):6324-37. doi: 10.1111/j.1742-4658.2009.07346.x. Epub 2009 Oct 1.

PMID:
19796173
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