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Results: 1 to 20 of 136

1.

EML4-ALK translocation in both metachronous second primary lung sarcomatoid carcinoma and lung adenocarcinoma: a case report.

Alì G, Proietti A, Niccoli C, Pelliccioni S, Borrelli N, Giannini R, Lupi C, Valetto A, Bertini V, Lucchi M, Mussi A, Fontanini G.

Lung Cancer. 2013 Aug;81(2):297-301. doi: 10.1016/j.lungcan.2013.03.016. Epub 2013 May 10.

PMID:
23664446
[PubMed - indexed for MEDLINE]
2.

Clinical significance of EML4-ALK fusion gene and association with EGFR and KRAS gene mutations in 208 Chinese patients with non-small cell lung cancer.

Li Y, Li Y, Yang T, Wei S, Wang J, Wang M, Wang Y, Zhou Q, Liu H, Chen J.

PLoS One. 2013;8(1):e52093. doi: 10.1371/journal.pone.0052093. Epub 2013 Jan 14.

PMID:
23341890
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

EML4-ALK translocation predicts better outcome in lung adenocarcinoma patients with wild-type EGFR.

Wu SG, Kuo YW, Chang YL, Shih JY, Chen YH, Tsai MF, Yu CJ, Yang CH, Yang PC.

J Thorac Oncol. 2012 Jan;7(1):98-104. doi: 10.1097/JTO.0b013e3182370e30.

PMID:
22124476
[PubMed - indexed for MEDLINE]
4.

Detection of ALK rearrangement by immunohistochemistry in lung adenocarcinoma and the identification of a novel EML4-ALK variant.

To KF, Tong JH, Yeung KS, Lung RW, Law PP, Chau SL, Kang W, Tong CY, Chow C, Chan AW, Leung LK, Mok TS.

J Thorac Oncol. 2013 Jul;8(7):883-91. doi: 10.1097/JTO.0b013e3182904e22.

PMID:
23625156
[PubMed - indexed for MEDLINE]
5.

ALK fusion gene positive lung cancer and 3 cases treated with an inhibitor for ALK kinase activity.

Kimura H, Nakajima T, Takeuchi K, Soda M, Mano H, Iizasa T, Matsui Y, Yoshino M, Shingyoji M, Itakura M, Itami M, Ikebe D, Yokoi S, Kageyama H, Ohira M, Nakagawara A.

Lung Cancer. 2012 Jan;75(1):66-72. doi: 10.1016/j.lungcan.2011.05.027. Epub 2011 Jul 14.

PMID:
21757253
[PubMed - indexed for MEDLINE]
6.

Detection of EML4-ALK fusion genes in non-small cell lung cancer patients with clinical features associated with EGFR mutations.

Shaozhang Z, Xiaomei L, Aiping Z, Jianbo H, Xiangqun S, Qitao Y.

Genes Chromosomes Cancer. 2012 Oct;51(10):925-32. doi: 10.1002/gcc.21976. Epub 2012 Jun 27.

PMID:
22736493
[PubMed - indexed for MEDLINE]
7.

Exon array profiling detects EML4-ALK fusion in breast, colorectal, and non-small cell lung cancers.

Lin E, Li L, Guan Y, Soriano R, Rivers CS, Mohan S, Pandita A, Tang J, Modrusan Z.

Mol Cancer Res. 2009 Sep;7(9):1466-76. doi: 10.1158/1541-7786.MCR-08-0522. Epub 2009 Sep 8.

PMID:
19737969
[PubMed - indexed for MEDLINE]
Free Article
8.

Evaluation of ALK rearrangement in Chinese non-small cell lung cancer using FISH, immunohistochemistry, and real-time quantitative RT- PCR on paraffin-embedded tissues.

Zhang YG, Jin ML, Li L, Zhao HY, Zeng X, Jiang L, Wei P, Diao XL, Li X, Cao Q, Tian XX.

PLoS One. 2013 May 31;8(5):e64821. doi: 10.1371/journal.pone.0064821. Print 2013.

PMID:
23741400
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

The biology and treatment of EML4-ALK non-small cell lung cancer.

Sasaki T, Rodig SJ, Chirieac LR, Jänne PA.

Eur J Cancer. 2010 Jul;46(10):1773-80. doi: 10.1016/j.ejca.2010.04.002. Epub 2010 Apr 24. Review.

PMID:
20418096
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Increased ALK gene copy number and amplification are frequent in non-small cell lung cancer.

Salido M, Pijuan L, Martínez-Avilés L, Galván AB, Cañadas I, Rovira A, Zanui M, Martínez A, Longarón R, Sole F, Serrano S, Bellosillo B, Wynes MW, Albanell J, Hirsch FR, Arriola E.

J Thorac Oncol. 2011 Jan;6(1):21-7. doi: 10.1097/JTO.0b013e3181fb7cd6.

PMID:
21107285
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK.

Shaw AT, Yeap BY, Mino-Kenudson M, Digumarthy SR, Costa DB, Heist RS, Solomon B, Stubbs H, Admane S, McDermott U, Settleman J, Kobayashi S, Mark EJ, Rodig SJ, Chirieac LR, Kwak EL, Lynch TJ, Iafrate AJ.

J Clin Oncol. 2009 Sep 10;27(26):4247-53. doi: 10.1200/JCO.2009.22.6993. Epub 2009 Aug 10.

PMID:
19667264
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Multiplex reverse transcription-PCR screening for EML4-ALK fusion transcripts.

Takeuchi K, Choi YL, Soda M, Inamura K, Togashi Y, Hatano S, Enomoto M, Takada S, Yamashita Y, Satoh Y, Okumura S, Nakagawa K, Ishikawa Y, Mano H.

Clin Cancer Res. 2008 Oct 15;14(20):6618-24. doi: 10.1158/1078-0432.CCR-08-1018.

PMID:
18927303
[PubMed - indexed for MEDLINE]
Free Article
13.

Anaplastic lymphoma kinase immunoreactivity correlates with ALK gene rearrangement and transcriptional up-regulation in non-small cell lung carcinomas.

Boland JM, Erdogan S, Vasmatzis G, Yang P, Tillmans LS, Johnson MR, Wang X, Peterson LM, Halling KC, Oliveira AM, Aubry MC, Yi ES.

Hum Pathol. 2009 Aug;40(8):1152-8. doi: 10.1016/j.humpath.2009.01.012. Epub 2009 Apr 22.

PMID:
19386350
[PubMed - indexed for MEDLINE]
14.

EML4-ALK rearrangement in non-small cell lung cancer and non-tumor lung tissues.

Martelli MP, Sozzi G, Hernandez L, Pettirossi V, Navarro A, Conte D, Gasparini P, Perrone F, Modena P, Pastorino U, Carbone A, Fabbri A, Sidoni A, Nakamura S, Gambacorta M, Fernández PL, Ramirez J, Chan JK, Grigioni WF, Campo E, Pileri SA, Falini B.

Am J Pathol. 2009 Feb;174(2):661-70. doi: 10.2353/ajpath.2009.080755. Epub 2009 Jan 15.

PMID:
19147828
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

The use of stained cytologic direct smears for ALK gene rearrangement analysis of lung adenocarcinoma.

Betz BL, Dixon CA, Weigelin HC, Knoepp SM, Roh MH.

Cancer Cytopathol. 2013 Sep;121(9):489-99. doi: 10.1002/cncy.21286. Epub 2013 Mar 27.

PMID:
23536384
[PubMed - indexed for MEDLINE]
16.

A novel EML4-ALK variant: exon 6 of EML4 fused to exon 19 of ALK.

Penzel R, Schirmacher P, Warth A.

J Thorac Oncol. 2012 Jul;7(7):1198-9. doi: 10.1097/JTO.0b013e3182598af3.

PMID:
22706607
[PubMed - indexed for MEDLINE]
17.

Fusion of EML4 and ALK is associated with development of lung adenocarcinomas lacking EGFR and KRAS mutations and is correlated with ALK expression.

Zhang X, Zhang S, Yang X, Yang J, Zhou Q, Yin L, An S, Lin J, Chen S, Xie Z, Zhu M, Zhang X, Wu YL.

Mol Cancer. 2010 Jul 13;9:188. doi: 10.1186/1476-4598-9-188.

PMID:
20624322
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

EML4-ALK fusion lung cancer: a rare acquired event.

Perner S, Wagner PL, Demichelis F, Mehra R, Lafargue CJ, Moss BJ, Arbogast S, Soltermann A, Weder W, Giordano TJ, Beer DG, Rickman DS, Chinnaiyan AM, Moch H, Rubin MA.

Neoplasia. 2008 Mar;10(3):298-302.

PMID:
18320074
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Isolated central nervous system progression on Crizotinib: an Achilles heel of non-small cell lung cancer with EML4-ALK translocation?

Chun SG, Choe KS, Iyengar P, Yordy JS, Timmerman RD.

Cancer Biol Ther. 2012 Dec;13(14):1376-83. doi: 10.4161/cbt.22255. Epub 2012 Sep 17.

PMID:
22986231
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

The EML4-ALK fusion gene is involved in various histologic types of lung cancers from nonsmokers with wild-type EGFR and KRAS.

Wong DW, Leung EL, So KK, Tam IY, Sihoe AD, Cheng LC, Ho KK, Au JS, Chung LP, Pik Wong M; University of Hong Kong Lung Cancer Study Group.

Cancer. 2009 Apr 15;115(8):1723-33. doi: 10.1002/cncr.24181.

PMID:
19170230
[PubMed - indexed for MEDLINE]
Free Article

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