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Endoplasmic reticulum stress-induced resistance to doxorubicin is reversed by paeonol treatment in human hepatocellular carcinoma cells.

Fan L, Song B, Sun G, Ma T, Zhong F, Wei W.

PLoS One. 2013 May 3;8(5):e62627. doi: 10.1371/journal.pone.0062627. Print 2013.


Dihydroartemisinin induces endoplasmic reticulum stress-mediated apoptosis in HepG2 human hepatoma cells.

Gao X, Luo Z, Xiang T, Wang K, Li J, Wang P.

Tumori. 2011 Nov-Dec;97(6):771-80. doi: 10.1700/1018.11095.


Bufalin Reverses Resistance to Sorafenib by Inhibiting Akt Activation in Hepatocellular Carcinoma: The Role of Endoplasmic Reticulum Stress.

Zhai B, Hu F, Yan H, Zhao D, Jin X, Fang T, Pan S, Sun X, Xu L.

PLoS One. 2015 Sep 18;10(9):e0138485. doi: 10.1371/journal.pone.0138485. eCollection 2015.


Elucidation of susceptible factors to endoplasmic reticulum stress-mediated anticancer activity in human hepatocellular carcinoma.

Chiang PC, Hsu JL, Yeh TC, Pan SL, Guh JH.

Naunyn Schmiedebergs Arch Pharmacol. 2008 Apr;377(2):167-77. doi: 10.1007/s00210-007-0249-4. Epub 2008 Jan 29.


Sensitization of TRAIL-induced cell death by 20(S)-ginsenoside Rg3 via CHOP-mediated DR5 upregulation in human hepatocellular carcinoma cells.

Lee JY, Jung KH, Morgan MJ, Kang YR, Lee HS, Koo GB, Hong SS, Kwon SW, Kim YS.

Mol Cancer Ther. 2013 Mar;12(3):274-85. doi: 10.1158/1535-7163.MCT-12-0054. Epub 2012 Oct 10.


Melatonin sensitizes human hepatoma cells to endoplasmic reticulum stress-induced apoptosis.

Zha L, Fan L, Sun G, Wang H, Ma T, Zhong F, Wei W.

J Pineal Res. 2012 Apr;52(3):322-31. doi: 10.1111/j.1600-079X.2011.00946.x. Epub 2012 Jan 8.


The Hsp90 inhibitor SNX-2112 induces apoptosis of human hepatocellular carcinoma cells: the role of ER stress.

Wang X, Wang S, Liu Y, Ding W, Zheng K, Xiang Y, Liu K, Wang D, Zeng Y, Xia M, Yang D, Wang Y.

Biochem Biophys Res Commun. 2014 Mar 28;446(1):160-6. doi: 10.1016/j.bbrc.2014.02.081. Epub 2014 Feb 25.


V8, a newly synthetic flavonoid, induces apoptosis through ROS-mediated ER stress pathway in hepatocellular carcinoma.

Zhang Y, Zhao L, Li X, Wang Y, Yao J, Wang H, Li F, Li Z, Guo Q.

Arch Toxicol. 2014 Jan;88(1):97-107. doi: 10.1007/s00204-013-1085-6. Epub 2013 Jul 9.


Galangin inhibits proliferation of hepatocellular carcinoma cells by inducing endoplasmic reticulum stress.

Su L, Chen X, Wu J, Lin B, Zhang H, Lan L, Luo H.

Food Chem Toxicol. 2013 Dec;62:810-6. doi: 10.1016/j.fct.2013.10.019. Epub 2013 Oct 22.


6-Shogaol induces apoptosis in human hepatocellular carcinoma cells and exhibits anti-tumor activity in vivo through endoplasmic reticulum stress.

Hu R, Zhou P, Peng YB, Xu X, Ma J, Liu Q, Zhang L, Wen XD, Qi LW, Gao N, Li P.

PLoS One. 2012;7(6):e39664. doi: 10.1371/journal.pone.0039664. Epub 2012 Jun 29.


Clusterin protects hepatocellular carcinoma cells from endoplasmic reticulum stress induced apoptosis through GRP78.

Wang C, Jiang K, Gao D, Kang X, Sun C, Zhang Q, Li Y, Sun L, Zhang S, Guo K, Liu Y.

PLoS One. 2013;8(2):e55981. doi: 10.1371/journal.pone.0055981. Epub 2013 Feb 14.


ADAM10 overexpression confers resistance to doxorubicin-induced apoptosis in hepatocellular carcinoma.

Yang CL, Jiang FQ, Xu F, Jiang GX.

Tumour Biol. 2012 Oct;33(5):1535-41. doi: 10.1007/s13277-012-0405-4. Epub 2012 May 13.


CHOP potentially co-operates with FOXO3a in neuronal cells to regulate PUMA and BIM expression in response to ER stress.

Ghosh AP, Klocke BJ, Ballestas ME, Roth KA.

PLoS One. 2012;7(6):e39586. doi: 10.1371/journal.pone.0039586. Epub 2012 Jun 28.


[Role of dysregulation of Bim in resistance of melanoma cells to endoplasmic reticulum stress-induced apoptosis].

Hou LL, Jin L, Han CC, Cheng B, Wang L, Zhang XD, Zhang LJ.

Zhonghua Zhong Liu Za Zhi. 2011 Jul;33(7):494-8. Chinese.


Tunicamycin potentiates cisplatin anticancer efficacy through the DPAGT1/Akt/ABCG2 pathway in mouse Xenograft models of human hepatocellular carcinoma.

Hou H, Sun H, Lu P, Ge C, Zhang L, Li H, Zhao F, Tian H, Zhang L, Chen T, Yao M, Li J.

Mol Cancer Ther. 2013 Dec;12(12):2874-84. doi: 10.1158/1535-7163.MCT-13-0201. Epub 2013 Oct 15.


ADAM17 mediates hypoxia-induced drug resistance in hepatocellular carcinoma cells through activation of EGFR/PI3K/Akt pathway.

Wang XJ, Feng CW, Li M.

Mol Cell Biochem. 2013 Aug;380(1-2):57-66. doi: 10.1007/s11010-013-1657-z. Epub 2013 Apr 28.


CD147 induces UPR to inhibit apoptosis and chemosensitivity by increasing the transcription of Bip in hepatocellular carcinoma.

Tang J, Guo YS, Zhang Y, Yu XL, Li L, Huang W, Li Y, Chen B, Jiang JL, Chen ZN.

Cell Death Differ. 2012 Nov;19(11):1779-90. doi: 10.1038/cdd.2012.60. Epub 2012 May 18.

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