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Items: 1 to 20 of 130

1.

Global genomic profiling reveals an extensive p53-regulated autophagy program contributing to key p53 responses.

Kenzelmann Broz D, Spano Mello S, Bieging KT, Jiang D, Dusek RL, Brady CA, Sidow A, Attardi LD.

Genes Dev. 2013 May 1;27(9):1016-31. doi: 10.1101/gad.212282.112.

2.

The family that eats together stays together: new p53 family transcriptional targets in autophagy.

Napoli M, Flores ER.

Genes Dev. 2013 May 1;27(9):971-4. doi: 10.1101/gad.219147.113.

3.

TRP53 activates a global autophagy program to promote tumor suppression.

Kenzelmann Broz D, Attardi LD.

Autophagy. 2013 Sep;9(9):1440-2. doi: 10.4161/auto.25833. Epub 2013 Jul 29.

4.

Characterization of the p53 cistrome--DNA binding cooperativity dissects p53's tumor suppressor functions.

Schlereth K, Heyl C, Krampitz AM, Mernberger M, Finkernagel F, Scharfe M, Jarek M, Leich E, Rosenwald A, Stiewe T.

PLoS Genet. 2013;9(8):e1003726. doi: 10.1371/journal.pgen.1003726. Epub 2013 Aug 15.

5.

ISG20L1 is a p53 family target gene that modulates genotoxic stress-induced autophagy.

Eby KG, Rosenbluth JM, Mays DJ, Marshall CB, Barton CE, Sinha S, Johnson KN, Tang L, Pietenpol JA.

Mol Cancer. 2010 Apr 29;9:95. doi: 10.1186/1476-4598-9-95.

6.

DN-p73 is activated after DNA damage in a p53-dependent manner to regulate p53-induced cell cycle arrest.

Vossio S, Palescandolo E, Pediconi N, Moretti F, Balsano C, Levrero M, Costanzo A.

Oncogene. 2002 May 23;21(23):3796-803.

7.

Genome-wide analysis of the p53 gene regulatory network in the developing mouse kidney.

Li Y, Liu J, McLaughlin N, Bachvarov D, Saifudeen Z, El-Dahr SS.

Physiol Genomics. 2013 Oct 16;45(20):948-64. doi: 10.1152/physiolgenomics.00113.2013. Epub 2013 Sep 3.

9.

Rap2b, a novel p53 target, regulates p53-mediated pro-survival function.

Zhang X, He Y, Lee KH, Dubois W, Li Z, Wu X, Kovalchuk A, Zhang W, Huang J.

Cell Cycle. 2013 Apr 15;12(8):1279-91. doi: 10.4161/cc.24364. Epub 2013 Mar 27.

10.

Identification and analysis of large intergenic non-coding RNAs regulated by p53 family members through a genome-wide analysis of p53-binding sites.

Idogawa M, Ohashi T, Sasaki Y, Maruyama R, Kashima L, Suzuki H, Tokino T.

Hum Mol Genet. 2014 Jun 1;23(11):2847-57. doi: 10.1093/hmg/ddt673. Epub 2014 Jan 8.

11.

Identification and characterization of the cytoplasmic protein TRAF4 as a p53-regulated proapoptotic gene.

Sax JK, El-Deiry WS.

J Biol Chem. 2003 Sep 19;278(38):36435-44. Epub 2003 Jun 4.

12.

p63 and p73 transcriptionally regulate genes involved in DNA repair.

Lin YL, Sengupta S, Gurdziel K, Bell GW, Jacks T, Flores ER.

PLoS Genet. 2009 Oct;5(10):e1000680. doi: 10.1371/journal.pgen.1000680. Epub 2009 Oct 9.

13.

Che-1 modulates the decision between cell cycle arrest and apoptosis by its binding to p53.

Desantis A, Bruno T, Catena V, De Nicola F, Goeman F, Iezzi S, Sorino C, Gentileschi MP, Germoni S, Monteleone V, Pellegrino M, Kann M, De Meo PD, Pallocca M, Höpker K, Moretti F, Mattei E, Reinhardt HC, Floridi A, Passananti C, Benzing T, Blandino G, Fanciulli M.

Cell Death Dis. 2015 May 21;6:e1764. doi: 10.1038/cddis.2015.117.

14.

p53FamTaG: a database resource of human p53, p63 and p73 direct target genes combining in silico prediction and microarray data.

Sbisà E, Catalano D, Grillo G, Licciulli F, Turi A, Liuni S, Pesole G, De Grassi A, Caratozzolo MF, D'Erchia AM, Navarro B, Tullo A, Saccone C, Gisel A.

BMC Bioinformatics. 2007 Mar 8;8 Suppl 1:S20.

15.

E2F7, a novel target, is up-regulated by p53 and mediates DNA damage-dependent transcriptional repression.

Carvajal LA, Hamard PJ, Tonnessen C, Manfredi JJ.

Genes Dev. 2012 Jul 15;26(14):1533-45. doi: 10.1101/gad.184911.111.

16.
17.

Gene expression profiling analysis reveals arsenic-induced cell cycle arrest and apoptosis in p53-proficient and p53-deficient cells through differential gene pathways.

Yu X, Robinson JF, Gribble E, Hong SW, Sidhu JS, Faustman EM.

Toxicol Appl Pharmacol. 2008 Dec 15;233(3):389-403. doi: 10.1016/j.taap.2008.09.016. Epub 2008 Sep 27.

18.

p53 efficiently suppresses tumor development in the complete absence of its cell-cycle inhibitory and proapoptotic effectors p21, Puma, and Noxa.

Valente LJ, Gray DH, Michalak EM, Pinon-Hofbauer J, Egle A, Scott CL, Janic A, Strasser A.

Cell Rep. 2013 May 30;3(5):1339-45. doi: 10.1016/j.celrep.2013.04.012. Epub 2013 May 9.

19.

p53 shapes genome-wide and cell type-specific changes in microRNA expression during the human DNA damage response.

Hattori H, Janky R, Nietfeld W, Aerts S, Madan Babu M, Venkitaraman AR.

Cell Cycle. 2014;13(16):2572-86. doi: 10.4161/15384101.2015.942209.

20.

Chromatin immunoprecipitation-on-chip reveals stress-dependent p53 occupancy in primary normal cells but not in established cell lines.

Shaked H, Shiff I, Kott-Gutkowski M, Siegfried Z, Haupt Y, Simon I.

Cancer Res. 2008 Dec 1;68(23):9671-7. doi: 10.1158/0008-5472.CAN-08-0865.

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