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Results: 1 to 20 of 97

1.

Isoprenoid biosynthesis: ferraoxetane or allyl anion mechanism for IspH catalysis?

Li J, Wang K, Smirnova TI, Khade RL, Zhang Y, Oldfield E.

Angew Chem Int Ed Engl. 2013 Jun 17;52(25):6522-5. doi: 10.1002/anie.201302343. Epub 2013 May 6. No abstract available.

PMID:
23649534
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Reductive dehydroxylation of allyl alcohols by IspH protein.

Gräwert T, Span I, Bacher A, Groll M.

Angew Chem Int Ed Engl. 2010 Nov 15;49(47):8802-9. doi: 10.1002/anie.201000833. Review.

PMID:
20922726
[PubMed - indexed for MEDLINE]
3.

Mechanistic studies of an IspH-catalyzed reaction: implications for substrate binding and protonation in the biosynthesis of isoprenoids.

Chang WC, Xiao Y, Liu HW, Liu P.

Angew Chem Int Ed Engl. 2011 Dec 16;50(51):12304-7. doi: 10.1002/anie.201104124. Epub 2011 Oct 24. No abstract available.

PMID:
22025241
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Are free radicals involved in IspH catalysis? An EPR and crystallographic investigation.

Wang W, Wang K, Span I, Jauch J, Bacher A, Groll M, Oldfield E.

J Am Chem Soc. 2012 Jul 11;134(27):11225-34. doi: 10.1021/ja303445z. Epub 2012 Jun 28.

PMID:
22687151
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Targeting isoprenoid biosynthesis for drug discovery: bench to bedside.

Oldfield E.

Acc Chem Res. 2010 Sep 21;43(9):1216-26. doi: 10.1021/ar100026v.

PMID:
20560544
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Bioorganometallic mechanism of action, and inhibition, of IspH.

Wang W, Wang K, Liu YL, No JH, Li J, Nilges MJ, Oldfield E.

Proc Natl Acad Sci U S A. 2010 Mar 9;107(10):4522-7. doi: 10.1073/pnas.0911087107. Epub 2010 Feb 19.

PMID:
20173096
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The Arabidopsis IspH homolog is involved in the plastid nonmevalonate pathway of isoprenoid biosynthesis.

Hsieh MH, Goodman HM.

Plant Physiol. 2005 Jun;138(2):641-53. Epub 2005 Apr 29.

PMID:
15863698
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Inhibition of IspH, a [4Fe-4S]2+ enzyme involved in the biosynthesis of isoprenoids via the methylerythritol phosphate pathway.

Janthawornpong K, Krasutsky S, Chaignon P, Rohmer M, Poulter CD, Seemann M.

J Am Chem Soc. 2013 Feb 6;135(5):1816-22. doi: 10.1021/ja309557s. Epub 2013 Jan 29.

PMID:
23316732
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Pyridine inhibitor binding to the 4Fe-4S protein A. aeolicus IspH (LytB): a HYSCORE Investigation.

Wang W, Li J, Wang K, Smirnova TI, Oldfield E.

J Am Chem Soc. 2011 May 4;133(17):6525-8. doi: 10.1021/ja2008455. Epub 2011 Apr 12.

PMID:
21486034
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

IspG converts an epoxide substrate analogue to (E)-4-hydroxy-3-methylbut-2-enyl diphosphate: implications for IspG catalysis in isoprenoid biosynthesis.

Nyland RL 2nd, Xiao Y, Liu P, Freel Meyers CL.

J Am Chem Soc. 2009 Dec 16;131(49):17734-5. doi: 10.1021/ja907470n.

PMID:
19919056
[PubMed - indexed for MEDLINE]
11.

Chimeras of two isoprenoid synthases catalyze all four coupling reactions in isoprenoid biosynthesis.

Thulasiram HV, Erickson HK, Poulter CD.

Science. 2007 Apr 6;316(5821):73-6.

PMID:
17412950
[PubMed - indexed for MEDLINE]
Free Article
12.

A proposed mechanism for the reductive ring opening of the cyclodiphosphate MEcPP, a crucial transformation in the new DXP/MEP pathway to isoprenoids based on modeling studies and feeding experiments.

Brandt W, Dessoy MA, Fulhorst M, Gao W, Zenk MH, Wessjohann LA.

Chembiochem. 2004 Mar 5;5(3):311-23.

PMID:
14997523
[PubMed - indexed for MEDLINE]
13.

Selective liquid phase hydrogenation of citral on Au/Fe2O3 catalysts.

Milone C, Tropeano ML, Gulino G, Neri G, Ingoglia R, Galvagno S.

Chem Commun (Camb). 2002 Apr 21;(8):868-9.

PMID:
12123019
[PubMed - indexed for MEDLINE]
14.

Methylerythritol phosphate pathway of isoprenoid biosynthesis.

Zhao L, Chang WC, Xiao Y, Liu HW, Liu P.

Annu Rev Biochem. 2013;82:497-530. doi: 10.1146/annurev-biochem-052010-100934. Review.

PMID:
23746261
[PubMed - indexed for MEDLINE]
15.

Isopentenyl diphosphate isomerase: A checkpoint to isoprenoid biosynthesis.

Berthelot K, Estevez Y, Deffieux A, Peruch F.

Biochimie. 2012 Aug;94(8):1621-34. doi: 10.1016/j.biochi.2012.03.021. Epub 2012 Apr 4. Review.

PMID:
22503704
[PubMed - indexed for MEDLINE]
16.

Isoprenoid biosynthesis: manifold chemistry catalyzed by similar enzymes.

Wendt KU, Schulz GE.

Structure. 1998 Feb 15;6(2):127-33. Review.

PMID:
9519404
[PubMed - indexed for MEDLINE]
17.

Discovery of acetylene hydratase activity of the iron-sulphur protein IspH.

Span I, Wang K, Wang W, Zhang Y, Bacher A, Eisenreich W, Li K, Schulz C, Oldfield E, Groll M.

Nat Commun. 2012;3:1042. doi: 10.1038/ncomms2052.

PMID:
22948824
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Biosynthesis of terpenes: studies on 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase.

Adam P, Hecht S, Eisenreich W, Kaiser J, Grawert T, Arigoni D, Bacher A, Rohdich F.

Proc Natl Acad Sci U S A. 2002 Sep 17;99(19):12108-13. Epub 2002 Aug 27.

PMID:
12198182
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Inhibition of the isoprenoid biosynthesis pathway; detection of intermediates by UPLC-MS/MS.

Henneman L, van Cruchten AG, Kulik W, Waterham HR.

Biochim Biophys Acta. 2011 Apr;1811(4):227-33. doi: 10.1016/j.bbalip.2011.01.002. Epub 2011 Jan 13.

PMID:
21237288
[PubMed - indexed for MEDLINE]
Free Article
20.

Functional analysis of the final steps of the 1-deoxy-D-xylulose 5-phosphate (DXP) pathway to isoprenoids in plants using virus-induced gene silencing.

Page JE, Hause G, Raschke M, Gao W, Schmidt J, Zenk MH, Kutchan TM.

Plant Physiol. 2004 Apr;134(4):1401-13. Epub 2004 Apr 2.

PMID:
15064370
[PubMed - indexed for MEDLINE]
Free PMC Article

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