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Results: 1 to 20 of 126

1.

MEN1 is a melanoma tumor suppressor that preserves genomic integrity by stimulating transcription of genes that promote homologous recombination-directed DNA repair.

Fang M, Xia F, Mahalingam M, Virbasius CM, Wajapeyee N, Green MR.

Mol Cell Biol. 2013 Jul;33(13):2635-47. doi: 10.1128/MCB.00167-13. Epub 2013 May 6.

PMID:
23648481
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

DNA-PK, ATM and ATR collaboratively regulate p53-RPA interaction to facilitate homologous recombination DNA repair.

Serrano MA, Li Z, Dangeti M, Musich PR, Patrick S, Roginskaya M, Cartwright B, Zou Y.

Oncogene. 2013 May 9;32(19):2452-62. doi: 10.1038/onc.2012.257. Epub 2012 Jul 16.

PMID:
22797063
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Differing effects of breast cancer 1, early onset (BRCA1) and ataxia-telangiectasia mutated (ATM) mutations on cellular responses to ionizing radiation.

Mamon HJ, Dahlberg W, Azzam EI, Nagasawa H, Muto MG, Little JB.

Int J Radiat Biol. 2003 Oct;79(10):817-29.

PMID:
14630541
[PubMed - indexed for MEDLINE]
4.

ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2.

Beucher A, Birraux J, Tchouandong L, Barton O, Shibata A, Conrad S, Goodarzi AA, Krempler A, Jeggo PA, Löbrich M.

EMBO J. 2009 Nov 4;28(21):3413-27. doi: 10.1038/emboj.2009.276. Epub 2009 Sep 24.

PMID:
19779458
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Functional characterization connects individual patient mutations in ataxia telangiectasia mutated (ATM) with dysfunction of specific DNA double-strand break-repair signaling pathways.

Keimling M, Volcic M, Csernok A, Wieland B, Dörk T, Wiesmüller L.

FASEB J. 2011 Nov;25(11):3849-60. doi: 10.1096/fj.11-185546. Epub 2011 Jul 21.

PMID:
21778326
[PubMed - indexed for MEDLINE]
Free Article
6.

Ataxia telangiectasia mutated and checkpoint kinase 2 regulate BRCA1 to promote the fidelity of DNA end-joining.

Wang HC, Chou WC, Shieh SY, Shen CY.

Cancer Res. 2006 Feb 1;66(3):1391-400.

PMID:
16452194
[PubMed - indexed for MEDLINE]
Free Article
7.

ATM-dependent MiR-335 targets CtIP and modulates the DNA damage response.

Martin NT, Nakamura K, Davies R, Nahas SA, Brown C, Tunuguntla R, Gatti RA, Hu H.

PLoS Genet. 2013 May;9(5):e1003505. doi: 10.1371/journal.pgen.1003505. Epub 2013 May 16.

PMID:
23696749
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair.

Zhang J, Willers H, Feng Z, Ghosh JC, Kim S, Weaver DT, Chung JH, Powell SN, Xia F.

Mol Cell Biol. 2004 Jan;24(2):708-18.

PMID:
14701743
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

53BP1 deficiency combined with telomere dysfunction activates ATR-dependent DNA damage response.

Martínez P, Flores JM, Blasco MA.

J Cell Biol. 2012 Apr 16;197(2):283-300. doi: 10.1083/jcb.201110124.

PMID:
22508511
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

miR-18a impairs DNA damage response through downregulation of ataxia telangiectasia mutated (ATM) kinase.

Song L, Lin C, Wu Z, Gong H, Zeng Y, Wu J, Li M, Li J.

PLoS One. 2011;6(9):e25454. doi: 10.1371/journal.pone.0025454. Epub 2011 Sep 27.

PMID:
21980462
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Estrogen receptor α-mediated transcription induces cell cycle-dependent DNA double-strand breaks.

Williamson LM, Lees-Miller SP.

Carcinogenesis. 2011 Mar;32(3):279-85. doi: 10.1093/carcin/bgq255. Epub 2010 Nov 26.

PMID:
21112959
[PubMed - indexed for MEDLINE]
Free Article
12.

Functional connection between Rad51 and PML in homology-directed repair.

Boichuk S, Hu L, Makielski K, Pandolfi PP, Gjoerup OV.

PLoS One. 2011;6(10):e25814. doi: 10.1371/journal.pone.0025814. Epub 2011 Oct 5.

PMID:
21998700
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

ATR-p53 restricts homologous recombination in response to replicative stress but does not limit DNA interstrand crosslink repair in lung cancer cells.

Sirbu BM, Lachmayer SJ, Wülfing V, Marten LM, Clarkson KE, Lee LW, Gheorghiu L, Zou L, Powell SN, Dahm-Daphi J, Willers H.

PLoS One. 2011;6(8):e23053. doi: 10.1371/journal.pone.0023053. Epub 2011 Aug 12.

PMID:
21857991
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Phosphorylation of Exo1 modulates homologous recombination repair of DNA double-strand breaks.

Bolderson E, Tomimatsu N, Richard DJ, Boucher D, Kumar R, Pandita TK, Burma S, Khanna KK.

Nucleic Acids Res. 2010 Apr;38(6):1821-31. doi: 10.1093/nar/gkp1164. Epub 2009 Dec 17.

PMID:
20019063
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

CBP and p300 histone acetyltransferases contribute to homologous recombination by transcriptionally activating the BRCA1 and RAD51 genes.

Ogiwara H, Kohno T.

PLoS One. 2012;7(12):e52810. doi: 10.1371/journal.pone.0052810. Epub 2012 Dec 20.

PMID:
23285190
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

RAD51 up-regulation bypasses BRCA1 function and is a common feature of BRCA1-deficient breast tumors.

Martin RW, Orelli BJ, Yamazoe M, Minn AJ, Takeda S, Bishop DK.

Cancer Res. 2007 Oct 15;67(20):9658-65.

PMID:
17942895
[PubMed - indexed for MEDLINE]
Free Article
17.

Triptolide induced DNA damage in A375.S2 human malignant melanoma cells is mediated via reduction of DNA repair genes.

Chueh FS, Chen YL, Hsu SC, Yang JS, Hsueh SC, Ji BC, Lu HF, Chung JG.

Oncol Rep. 2013 Feb;29(2):613-8. doi: 10.3892/or.2012.2170. Epub 2012 Dec 7.

PMID:
23233170
[PubMed - indexed for MEDLINE]
18.

Methotrexate-mediated inhibition of RAD51 expression and homologous recombination in cancer cells.

Du LQ, Du XQ, Bai JQ, Wang Y, Yang QS, Wang XC, Zhao P, Wang H, Liu Q, Fan FY.

J Cancer Res Clin Oncol. 2012 May;138(5):811-8. doi: 10.1007/s00432-011-1132-8. Epub 2012 Jan 25.

PMID:
22274865
[PubMed - indexed for MEDLINE]
19.

Investigation of switch from ATM to ATR signaling at the sites of DNA damage induced by low and high LET radiation.

Saha J, Wang M, Cucinotta FA.

DNA Repair (Amst). 2013 Dec;12(12):1143-51. doi: 10.1016/j.dnarep.2013.10.004. Epub 2013 Nov 12.

PMID:
24238855
[PubMed - indexed for MEDLINE]
20.

Ataxia telangiectasia mutated (ATM) kinase and ATM and Rad3 related kinase mediate phosphorylation of Brca1 at distinct and overlapping sites. In vivo assessment using phospho-specific antibodies.

Gatei M, Zhou BB, Hobson K, Scott S, Young D, Khanna KK.

J Biol Chem. 2001 May 18;276(20):17276-80. Epub 2001 Feb 13.

PMID:
11278964
[PubMed - indexed for MEDLINE]
Free Article

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