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Results: 1 to 20 of 279

1.

Odontogenic ameloblast-associated protein (ODAM) inhibits growth and migration of human melanoma cells and elicits PTEN elevation and inactivation of PI3K/AKT signaling.

Foster JS, Fish LM, Phipps JE, Bruker CT, Lewis JM, Bell JL, Solomon A, Kestler DP.

BMC Cancer. 2013 May 7;13:227. doi: 10.1186/1471-2407-13-227.

PMID:
23648148
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

PTEN sensitizes MDA-MB-468 cells to inhibition of MEK/Erk signaling for the blockade of cell proliferation.

Jang K, Kim M, Seo HS, Shin I.

Oncol Rep. 2010 Sep;24(3):787-93.

PMID:
20664988
[PubMed - indexed for MEDLINE]
3.

Estrogen receptor β represses Akt signaling in breast cancer cells via downregulation of HER2/HER3 and upregulation of PTEN: implications for tamoxifen sensitivity.

Lindberg K, Helguero LA, Omoto Y, Gustafsson JÅ, Haldosén LA.

Breast Cancer Res. 2011 Apr 14;13(2):R43. doi: 10.1186/bcr2865.

PMID:
21492444
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

PTEN regulates angiogenesis through PI3K/Akt/VEGF signaling pathway in human pancreatic cancer cells.

Ma J, Sawai H, Ochi N, Matsuo Y, Xu D, Yasuda A, Takahashi H, Wakasugi T, Takeyama H.

Mol Cell Biochem. 2009 Nov;331(1-2):161-71. doi: 10.1007/s11010-009-0154-x. Epub 2009 May 13.

PMID:
19437103
[PubMed - indexed for MEDLINE]
5.

IGF-1 mediates PTEN suppression and enhances cell invasion and proliferation via activation of the IGF-1/PI3K/Akt signaling pathway in pancreatic cancer cells.

Ma J, Sawai H, Matsuo Y, Ochi N, Yasuda A, Takahashi H, Wakasugi T, Funahashi H, Sato M, Takeyama H.

J Surg Res. 2010 May 1;160(1):90-101. doi: 10.1016/j.jss.2008.08.016. Epub 2008 Sep 13.

PMID:
19560785
[PubMed - indexed for MEDLINE]
6.

NOTCH1 functions as an oncogene by regulating the PTEN/PI3K/AKT pathway in clear cell renal cell carcinoma.

Liu S, Ma X, Ai Q, Huang Q, Shi T, Zhu M, Wang B, Zhang X.

Urol Oncol. 2013 Aug;31(6):938-48. doi: 10.1016/j.urolonc.2011.07.006. Epub 2011 Oct 10.

PMID:
21993533
[PubMed - indexed for MEDLINE]
7.

Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance.

McCubrey JA, Steelman LS, Abrams SL, Lee JT, Chang F, Bertrand FE, Navolanic PM, Terrian DM, Franklin RA, D'Assoro AB, Salisbury JL, Mazzarino MC, Stivala F, Libra M.

Adv Enzyme Regul. 2006;46:249-79. Epub 2006 Jul 18.

PMID:
16854453
[PubMed - indexed for MEDLINE]
8.

Estrogen receptor α induces down-regulation of PTEN through PI3-kinase activation in breast cancer cells.

Noh EM, Lee YR, Chay KO, Chung EY, Jung SH, Kim JS, Youn HJ.

Mol Med Rep. 2011 Mar-Apr;4(2):215-9. doi: 10.3892/mmr.2011.412. Epub 2011 Jan 3.

PMID:
21468554
[PubMed - indexed for MEDLINE]
9.

PTEN's regulation of VEGF and VEGFR1 expression and its clinical significance in myeloid leukemia.

Zhiyong C, Wentong L, Xiaoyang Y, Ling P.

Med Oncol. 2012 Jun;29(2):1084-92. doi: 10.1007/s12032-011-9867-2. Epub 2011 Mar 1.

PMID:
21360018
[PubMed - indexed for MEDLINE]
10.

MiR-21 regulates biological behavior through the PTEN/PI-3 K/Akt signaling pathway in human colorectal cancer cells.

Xiong B, Cheng Y, Ma L, Zhang C.

Int J Oncol. 2013 Jan;42(1):219-28. doi: 10.3892/ijo.2012.1707. Epub 2012 Nov 20.

PMID:
23174819
[PubMed - indexed for MEDLINE]
11.

Frequent PTEN genomic alterations and activated phosphatidylinositol 3-kinase pathway in basal-like breast cancer cells.

Marty B, Maire V, Gravier E, Rigaill G, Vincent-Salomon A, Kappler M, Lebigot I, Djelti F, Tourdès A, Gestraud P, Hupé P, Barillot E, Cruzalegui F, Tucker GC, Stern MH, Thiery JP, Hickman JA, Dubois T.

Breast Cancer Res. 2008;10(6):R101. doi: 10.1186/bcr2204. Epub 2008 Dec 3.

PMID:
19055754
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Opposite regulation by PI3K/Akt and MAPK/ERK pathways of tissue factor expression, cell-associated procoagulant activity and invasiveness in MDA-MB-231 cells.

Hu C, Huang L, Gest C, Xi X, Janin A, Soria C, Li H, Lu H.

J Hematol Oncol. 2012 Jul 11;5:16. doi: 10.1186/1756-8722-5-16.

PMID:
22534171
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

TOPK/PBK promotes cell migration via modulation of the PI3K/PTEN/AKT pathway and is associated with poor prognosis in lung cancer.

Shih MC, Chen JY, Wu YC, Jan YH, Yang BM, Lu PJ, Cheng HC, Huang MS, Yang CJ, Hsiao M, Lai JM.

Oncogene. 2012 May 10;31(19):2389-400. doi: 10.1038/onc.2011.419. Epub 2011 Sep 26.

PMID:
21996732
[PubMed - indexed for MEDLINE]
14.

Exogenous PTEN gene induces apoptosis in breast carcinoma cell line MDA468.

Chen Q, Wang C, Jiang C, Chen D.

J Huazhong Univ Sci Technolog Med Sci. 2007 Feb;27(1):61-4.

PMID:
17393112
[PubMed - indexed for MEDLINE]
15.

Inositol polyphosphate 4-phosphatase II regulates PI3K/Akt signaling and is lost in human basal-like breast cancers.

Fedele CG, Ooms LM, Ho M, Vieusseux J, O'Toole SA, Millar EK, Lopez-Knowles E, Sriratana A, Gurung R, Baglietto L, Giles GG, Bailey CG, Rasko JE, Shields BJ, Price JT, Majerus PW, Sutherland RL, Tiganis T, McLean CA, Mitchell CA.

Proc Natl Acad Sci U S A. 2010 Dec 21;107(51):22231-6. doi: 10.1073/pnas.1015245107. Epub 2010 Dec 2.

PMID:
21127264
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Basal and treatment-induced activation of AKT mediates resistance to cell death by AZD6244 (ARRY-142886) in Braf-mutant human cutaneous melanoma cells.

Gopal YN, Deng W, Woodman SE, Komurov K, Ram P, Smith PD, Davies MA.

Cancer Res. 2010 Nov 1;70(21):8736-47. doi: 10.1158/0008-5472.CAN-10-0902. Epub 2010 Oct 19.

PMID:
20959481
[PubMed - indexed for MEDLINE]
Free Article
17.

PTEN suppresses breast cancer cell growth by phosphatase activity-dependent G1 arrest followed by cell death.

Weng LP, Smith WM, Dahia PL, Ziebold U, Gil E, Lees JA, Eng C.

Cancer Res. 1999 Nov 15;59(22):5808-14.

PMID:
10582703
[PubMed - indexed for MEDLINE]
Free Article
18.

Src family protein-tyrosine kinases alter the function of PTEN to regulate phosphatidylinositol 3-kinase/AKT cascades.

Lu Y, Yu Q, Liu JH, Zhang J, Wang H, Koul D, McMurray JS, Fang X, Yung WK, Siminovitch KA, Mills GB.

J Biol Chem. 2003 Oct 10;278(41):40057-66. Epub 2003 Jul 17.

PMID:
12869565
[PubMed - indexed for MEDLINE]
Free Article
19.

[Effects of Astragalus polysaccharide on proliferation and Akt phosphorylation of the basal-like breast cancer cell line].

Ye MN, Chen HF, Zhou RJ, Liao MJ.

Zhong Xi Yi Jie He Xue Bao. 2011 Dec;9(12):1339-46. Chinese.

PMID:
22152773
[PubMed - indexed for MEDLINE]
Free Article
20.

Tumour suppressor PTEN regulates cell cycle and protein kinase B/Akt pathway in breast cancer cells.

Hlobilkova A, Knillova J, Svachova M, Skypalova P, Krystof V, Kolar Z.

Anticancer Res. 2006 Mar-Apr;26(2A):1015-22.

PMID:
16619501
[PubMed - indexed for MEDLINE]
Free Article

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