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Items: 1 to 20 of 136

1.

Lipid emulsion-mediated reversal of toxic-dose aminoamide local anesthetic-induced vasodilation in isolated rat aorta.

Ok SH, Han JY, Lee SH, Shin IW, Lee HK, Chung YK, Choi MJ, Sohn JT.

Korean J Anesthesiol. 2013 Apr;64(4):353-9. doi: 10.4097/kjae.2013.64.4.353. Epub 2013 Apr 22.

2.

Effect of two lipid emulsions on reversing high-dose levobupivacaine-induced reduced vasoconstriction in the rat aortas.

Ok SH, Park CS, Kim HJ, Lee SH, Choi BH, Eun SY, Kim KN, Yang SM, Shin IW, Choi MJ, Sohn JT.

Cardiovasc Toxicol. 2013 Dec;13(4):370-80. doi: 10.1007/s12012-013-9218-y.

PMID:
23877627
3.

Lipid emulsions enhance the norepinephrine-mediated reversal of local anesthetic-induced vasodilation at toxic doses.

Lee SH, Sung HJ, Ok SH, Yu J, Choi MJ, Lim JS, Sohn JT.

Yonsei Med J. 2013 Nov;54(6):1524-32. doi: 10.3349/ymj.2013.54.6.1524.

4.

Lipid Emulsion Attenuates Acetylcholine-Induced Relaxation in Isolated Rat Aorta.

Ok SH, Lee SH, Yu J, Park J, Shin IW, Lee Y, Cho H, Choi MJ, Baik J, Hong JM, Han JY, Lee HK, Chung YK, Sohn JT.

Biomed Res Int. 2015;2015:871545. doi: 10.1155/2015/871545. Epub 2015 Jul 27.

5.

Lipid resuscitation of bupivacaine toxicity: long-chain triglyceride emulsion provides benefits over long- and medium-chain triglyceride emulsion.

Li Z, Xia Y, Dong X, Chen H, Xia F, Wang X, Dong H, Jin Z, Ding X, Papadimos TJ, Xu X.

Anesthesiology. 2011 Dec;115(6):1219-28. doi: 10.1097/ALN.0b013e318238be73.

PMID:
22037638
6.

A mixed (long- and medium-chain) triglyceride lipid emulsion extracts local anesthetic from human serum in vitro more effectively than a long-chain emulsion.

Ruan W, French D, Wong A, Drasner K, Wu AH.

Anesthesiology. 2012 Feb;116(2):334-9. doi: 10.1097/ALN.0b013e318242a5f1.

PMID:
22273855
7.

Lipid Emulsion Inhibits Vasodilation Induced by a Toxic Dose of Bupivacaine via Attenuated Dephosphorylation of Myosin Phosphatase Target Subunit 1 in Isolated Rat Aorta.

Ok SH, Byon HJ, Kwon SC, Park J, Lee Y, Hwang Y, Baik J, Choi MJ, Sohn JT.

Int J Med Sci. 2015 Nov 5;12(12):958-67. doi: 10.7150/ijms.13299. eCollection 2015.

8.

Binding of long-lasting local anesthetics to lipid emulsions.

Mazoit JX, Le Guen R, Beloeil H, Benhamou D.

Anesthesiology. 2009 Feb;110(2):380-6. doi: 10.1097/ALN.0b013e318194b252.

PMID:
19194164
9.

Lipofundin® MCT/LCT 20% increase left ventricular systolic pressure in an ex vivo rat heart model via increase of intracellular calcium level.

Park J, Kim YA, Han JY, Jin S, Ok SH, Sohn JT, Lee HK, Chung YK, Shin IW.

Korean J Anesthesiol. 2016 Feb;69(1):57-62. doi: 10.4097/kjae.2016.69.1.57. Epub 2016 Jan 28.

10.

The distinct effects of lipid emulsions used for "lipid resuscitation" on gating and bupivacaine-induced inhibition of the cardiac sodium channel Nav1.5.

Nadrowitz F, Stoetzer C, Foadi N, Ahrens J, Wegner F, Lampert A, Koppert W, de la Roche J, Leffler A.

Anesth Analg. 2013 Nov;117(5):1101-8. doi: 10.1213/ANE.0b013e3182a1af78.

PMID:
24029851
11.

Bupivacaine-induced Vasodilation Is Mediated by Decreased Calcium Sensitization in Isolated Endothelium-denuded Rat Aortas Precontracted with Phenylephrine.

Ok SH, Bae SI, Kwon SC, Park JC, Kim WC, Park KE, Shin IW, Lee HK, Chung YK, Choi MJ, Sohn JT.

Korean J Pain. 2014 Jul;27(3):229-38. doi: 10.3344/kjp.2014.27.3.229. Epub 2014 Jun 30.

12.

Reversal of bupivacaine-induced cardiac electrophysiologic changes by two lipid emulsions in anesthetized and mechanically ventilated piglets.

Candela D, Louart G, Bousquet PJ, Muller L, Nguyen M, Boyer JC, Peray PA, Goret L, Ripart J, Lefrant JY, de La Coussaye JE.

Anesth Analg. 2010 May 1;110(5):1473-9. doi: 10.1213/ANE.0b013e3181d53c8d.

PMID:
20418308
13.

Use of lipid emulsion to reverse local anesthetic-induced toxicity.

Corman SL, Skledar SJ.

Ann Pharmacother. 2007 Nov;41(11):1873-7. Epub 2007 Sep 25. Review.

PMID:
17895327
14.

The Effect of Lipid Emulsion on Pharmacokinetics of Bupivacaine in Rats: Long-Chain Triglyceride Versus Long- and Medium-Chain Triglyceride.

Tang W, Wang Q, Shi K, Dong J, Lin S, Zhao S, Wu C, Xia Y, Papadimos TJ, Xu X.

Anesth Analg. 2016 May 24. [Epub ahead of print]

PMID:
27224931
15.

Intravenous lipid emulsion only minimally influences bupivacaine and mepivacaine distribution in plasma and does not enhance recovery from intoxication in pigs.

Litonius ES, Niiya T, Neuvonen PJ, Rosenberg PH.

Anesth Analg. 2012 Apr;114(4):901-6. doi: 10.1213/ANE.0b013e3182367a37. Epub 2011 Oct 24.

PMID:
22025489
16.

Procaine and mepivacaine have less toxicity in vitro than other clinically used local anesthetics.

Kasaba T, Onizuka S, Takasaki M.

Anesth Analg. 2003 Jul;97(1):85-90, table of contents.

PMID:
12818948
17.

Differential effects of short- and long-term bupivacaine treatment on ╬▒1-adrenoceptor-mediated contraction of isolated rat aorta rings and the reversal effect of lipid emulsion.

Guo H, Zhang HF, Xu WQ, Du Q, Zhao J, Ren LM.

Acta Pharmacol Sin. 2015 Aug;36(8):976-86. doi: 10.1038/aps.2015.40. Epub 2015 Jun 15.

18.

Influence of structurally different lipid emulsions on human neutrophil oxygen radical production.

Wanten GJ, Naber AH, Kruimel JW, Tool AT, Roos D, Jansen JB.

Eur J Clin Invest. 1999 Apr;29(4):357-63.

PMID:
10231349
19.

Effects of Acidification and Alkalinization on the Lipid Emulsion-Mediated Reversal of Toxic Dose Levobupivacaine-Induced Vasodilation in the Isolated Rat Aorta.

Ok SH, Kim WH, Yu J, Lee Y, Choi MJ, Lim DH, Hwang Y, Kim YA, Sohn JT.

Int J Med Sci. 2016 Jan 25;13(1):68-76. doi: 10.7150/ijms.13016. eCollection 2016.

20.

Vasoconstriction potency induced by aminoamide local anesthetics correlates with lipid solubility.

Sung HJ, Ok SH, Sohn JY, Son YH, Kim JK, Lee SH, Han JY, Lim DH, Shin IW, Lee HK, Chung YK, Choi MJ, Sohn JT.

J Biomed Biotechnol. 2012;2012:170958. doi: 10.1155/2012/170958. Epub 2012 Jun 17.

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