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1.

Longitudinal monitoring of cardiac siderosis using cardiovascular magnetic resonance T2* in patients with thalassemia major on various chelation regimens: a 6-year study.

Ambati SR, Randolph RE, Mennitt K, Kleinert DA, Weinsaft JW, Giardina PJ.

Am J Hematol. 2013 Aug;88(8):652-6. doi: 10.1002/ajh.23469. Epub 2013 Jun 28.

2.

Low prevalence of cardiac siderosis in heavily iron loaded Egyptian thalassemia major patients.

El Beshlawy A, El Tagui M, Hamdy M, El Ghamrawy M, Azim KA, Salem D, Said F, Samir A, St Pierre T, Pennell DJ.

Ann Hematol. 2014 Mar;93(3):375-9. doi: 10.1007/s00277-013-1876-0. Epub 2013 Aug 15.

PMID:
23949317
3.

Combined chelation therapy in thalassemia major for the treatment of severe myocardial siderosis with left ventricular dysfunction.

Tanner MA, Galanello R, Dessi C, Smith GC, Westwood MA, Agus A, Pibiri M, Nair SV, Walker JM, Pennell DJ.

J Cardiovasc Magn Reson. 2008 Feb 25;10:12. doi: 10.1186/1532-429X-10-12.

4.

comparison of effects of different long-term iron-chelation regimens on myocardial and hepatic iron concentrations assessed with T2* magnetic resonance imaging in patients with beta-thalassemia major.

Perifanis V, Christoforidis A, Vlachaki E, Tsatra I, Spanos G, Athanassiou-Metaxa M.

Int J Hematol. 2007 Dec;86(5):385-9. doi: 10.1532/IJH97.E0734.

PMID:
18192103
5.

Cardiac iron removal and functional cardiac improvement by different iron chelation regimens in thalassemia major patients.

Cassinerio E, Roghi A, Pedrotti P, Brevi F, Zanaboni L, Graziadei G, Pattoneri P, Milazzo A, Cappellini MD.

Ann Hematol. 2012 Sep;91(9):1443-9. doi: 10.1007/s00277-012-1480-8. Epub 2012 May 10.

PMID:
22572843
6.

Effects of combined deferiprone with deferoxamine on right ventricular function in thalassaemia major.

Alpendurada F, Smith GC, Carpenter JP, Nair SV, Tanner MA, Banya W, Dessi C, Galanello R, Walker JM, Pennell DJ.

J Cardiovasc Magn Reson. 2012 Jan 25;14:8. doi: 10.1186/1532-429X-14-8.

7.

Deferasirox (Exjade) significantly improves cardiac T2* in heavily iron-overloaded patients with beta-thalassemia major.

Pathare A, Taher A, Daar S.

Ann Hematol. 2010 Apr;89(4):405-9. doi: 10.1007/s00277-009-0838-z. Epub 2009 Oct 2.

8.

Cardiac T2* MRI assessment in patients with thalassaemia major and its effect on the preference of chelation therapy.

Akcay A, Salcioglu Z, Oztarhan K, Tugcu D, Aydogan G, Ayaz NA, Bornaun H, Sen HS, Akici F, Akdana B.

Int J Hematol. 2014 Jun;99(6):706-13. doi: 10.1007/s12185-014-1575-1. Epub 2014 Apr 10.

PMID:
24719246
9.

Continued improvement in myocardial T2* over two years of deferasirox therapy in β-thalassemia major patients with cardiac iron overload.

Pennell DJ, Porter JB, Cappellini MD, Chan LL, El-Beshlawy A, Aydinok Y, Ibrahim H, Li CK, Viprakasit V, Elalfy MS, Kattamis A, Smith G, Habr D, Domokos G, Roubert B, Taher A.

Haematologica. 2011 Jan;96(1):48-54. doi: 10.3324/haematol.2010.031468. Epub 2010 Nov 11.

10.

Intermediate-term evaluation of a pratical chelation protocol based on stratification of thalassemic patients by serum ferritin and magnetic resonance imaging cardiac t2*.

Ha SY, Mok AS, Chu WC, Rasalkar DD, Cheuk DK, Chiang AK, Ho MH, Chan GC.

Hemoglobin. 2011;35(3):199-205. doi: 10.3109/03630269.2011.579007.

PMID:
21599432
11.

On improvement in ejection fraction with iron chelation in thalassemia major and the risk of future heart failure.

Pennell DJ, Carpenter JP, Roughton M, Cabantchik Z.

J Cardiovasc Magn Reson. 2011 Sep 12;13:45. doi: 10.1186/1532-429X-13-45.

12.

Efficacy of deferasirox in reducing and preventing cardiac iron overload in beta-thalassemia.

Pennell DJ, Porter JB, Cappellini MD, El-Beshlawy A, Chan LL, Aydinok Y, Elalfy MS, Sutcharitchan P, Li CK, Ibrahim H, Viprakasit V, Kattamis A, Smith G, Habr D, Domokos G, Roubert B, Taher A.

Blood. 2010 Mar 25;115(12):2364-71. doi: 10.1182/blood-2009-04-217455. Epub 2009 Dec 8.

13.

The relationship between the myocardial T2* value and left ventricular volumetric and functional parameters in thalassemia major patients.

Bayraktaroğlu S, Aydinok Y, Yildiz D, Uluer H, Savaş R, Alper H.

Diagn Interv Radiol. 2011 Dec;17(4):346-51. doi: 10.4261/1305-3825.DIR.3933-10.2. Epub 2011 Jun 6.

14.

MRI guided iron assessment and oral chelator use improve iron status in thalassemia major patients.

Nichols-Vinueza DX, White MT, Powell AJ, Banka P, Neufeld EJ.

Am J Hematol. 2014 Jul;89(7):684-8. doi: 10.1002/ajh.23715. Epub 2014 Apr 10.

PMID:
24652616
15.

Cardiac T2* magnetic resonance for prediction of cardiac complications in thalassemia major.

Kirk P, Roughton M, Porter JB, Walker JM, Tanner MA, Patel J, Wu D, Taylor J, Westwood MA, Anderson LJ, Pennell DJ.

Circulation. 2009 Nov 17;120(20):1961-8. doi: 10.1161/CIRCULATIONAHA.109.874487. Epub 2009 Oct 2.

16.

Evaluation of cardiac iron load by cardiac magnetic resonance in thalassemia.

Merchant R, Joshi A, Ahmed J, Krishnan P, Jankharia B.

Indian Pediatr. 2011 Sep;48(9):697-701. Epub 2010 Nov 30.

PMID:
21169646
17.

Relationship of magnetic resonance imaging estimation of myocardial iron to left ventricular systolic and diastolic function in thalassemia.

Leonardi B, Margossian R, Colan SD, Powell AJ.

JACC Cardiovasc Imaging. 2008 Sep;1(5):572-8. doi: 10.1016/j.jcmg.2008.04.005.

18.

How early can myocardial iron overload occur in beta thalassemia major?

Yang G, Liu R, Peng P, Long L, Zhang X, Yang W, Tan S, Pan H, Long X, He T, Anderson L, Lai Y.

PLoS One. 2014 Jan 22;9(1):e85379. doi: 10.1371/journal.pone.0085379. eCollection 2014.

19.

A practical chelation protocol based on stratification of thalassemic patients by serum ferritin and magnetic resonance imaging cardiac T2*.

Ha SY, Mok AS, Chu WC, Raskalkar DD, Cheuk DK, Chiang AK, Ho MH, Chan GC.

Hemoglobin. 2009;33(5):323-31. doi: 10.3109/03630260903211979.

PMID:
19814678
20.

Deferasirox for up to 3 years leads to continued improvement of myocardial T2* in patients with β-thalassemia major.

Pennell DJ, Porter JB, Cappellini MD, Chan LL, El-Beshlawy A, Aydinok Y, Ibrahim H, Li CK, Viprakasit V, Elalfy MS, Kattamis A, Smith G, Habr D, Domokos G, Roubert B, Taher A.

Haematologica. 2012 Jun;97(6):842-8. doi: 10.3324/haematol.2011.049957. Epub 2012 Jan 22.

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