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Items: 1 to 20 of 142

1.

Efficacious proteasome/HDAC inhibitor combination therapy for primary effusion lymphoma.

Bhatt S, Ashlock BM, Toomey NL, Diaz LA, Mesri EA, Lossos IS, Ramos JC.

J Clin Invest. 2013 Jun;123(6):2616-28. doi: 10.1172/JCI64503. Epub 2013 May 1.

2.

Efficacy of bortezomib in a direct xenograft model of primary effusion lymphoma.

Sarosiek KA, Cavallin LE, Bhatt S, Toomey NL, Natkunam Y, Blasini W, Gentles AJ, Ramos JC, Mesri EA, Lossos IS.

Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13069-74. doi: 10.1073/pnas.1002985107. Epub 2010 Jul 6.

3.

Targeting Myc in KSHV-associated primary effusion lymphoma with BET bromodomain inhibitors.

Tolani B, Gopalakrishnan R, Punj V, Matta H, Chaudhary PM.

Oncogene. 2014 May 29;33(22):2928-37. doi: 10.1038/onc.2013.242. Epub 2013 Jun 24.

PMID:
23792448
4.

Inhibition of KSHV-infected primary effusion lymphomas in NOD/SCID mice by gamma-secretase inhibitor.

Lan K, Murakami M, Bajaj B, Kaul R, He Z, Gan R, Feldman M, Robertson ES.

Cancer Biol Ther. 2009 Nov;8(22):2136-43. Epub 2009 Nov 7.

PMID:
19783901
5.

Pyrrolidinium fullerene induces apoptosis by activation of procaspase-9 via suppression of Akt in primary effusion lymphoma.

Watanabe T, Nakamura S, Ono T, Ui S, Yagi S, Kagawa H, Watanabe H, Ohe T, Mashino T, Fujimuro M.

Biochem Biophys Res Commun. 2014 Aug 15;451(1):93-100. doi: 10.1016/j.bbrc.2014.07.068. Epub 2014 Jul 22.

PMID:
25063029
6.

Proteasome inhibitors induce apoptosis and reduce viral replication in primary effusion lymphoma cells.

Saji C, Higashi C, Niinaka Y, Yamada K, Noguchi K, Fujimuro M.

Biochem Biophys Res Commun. 2011 Dec 2;415(4):573-8. doi: 10.1016/j.bbrc.2011.10.107. Epub 2011 Oct 31.

PMID:
22074820
7.
8.

Combination of SAHA and bortezomib up-regulates CDKN2A and CDKN1A and induces apoptosis of Epstein-Barr virus-positive Wp-restricted Burkitt lymphoma and lymphoblastoid cell lines.

Hui KF, Leung YY, Yeung PL, Middeldorp JM, Chiang AK.

Br J Haematol. 2014 Dec;167(5):639-50. doi: 10.1111/bjh.13089. Epub 2014 Aug 25.

PMID:
25155625
9.

The effects of heat shock protein 90 inhibitors on apoptosis and viral replication in primary effusion lymphoma cells.

Higashi C, Saji C, Yamada K, Kagawa H, Ohga R, Taira T, Fujimuro M.

Biol Pharm Bull. 2012;35(5):725-30.

10.
11.

Synergistic activity of bortezomib and HDACi in preclinical models of B-cell precursor acute lymphoblastic leukemia via modulation of p53, PI3K/AKT, and NF-κB.

Bastian L, Hof J, Pfau M, Fichtner I, Eckert C, Henze G, Prada J, von Stackelberg A, Seeger K, Shalapour S.

Clin Cancer Res. 2013 Mar 15;19(6):1445-57. doi: 10.1158/1078-0432.CCR-12-1511. Epub 2013 Jan 28.

12.

PS-341 or a combination of arsenic trioxide and interferon-alpha inhibit growth and induce caspase-dependent apoptosis in KSHV/HHV-8-infected primary effusion lymphoma cells.

Abou-Merhi R, Khoriaty R, Arnoult D, El Hajj H, Dbouk H, Munier S, El-Sabban ME, Hermine O, Gessain A, de Thé H, Mahieux R, Bazarbachi A.

Leukemia. 2007 Aug;21(8):1792-801. Epub 2007 Jun 14.

PMID:
17568816
13.

A purine scaffold HSP90 inhibitor BIIB021 has selective activity against KSHV-associated primary effusion lymphoma and blocks vFLIP K13-induced NF-κB.

Gopalakrishnan R, Matta H, Chaudhary PM.

Clin Cancer Res. 2013 Sep 15;19(18):5016-26. doi: 10.1158/1078-0432.CCR-12-3510. Epub 2013 Jul 23.

14.

Biscoclaurine alkaloid cepharanthine inhibits the growth of primary effusion lymphoma in vitro and in vivo and induces apoptosis via suppression of the NF-kappaB pathway.

Takahashi-Makise N, Suzu S, Hiyoshi M, Ohsugi T, Katano H, Umezawa K, Okada S.

Int J Cancer. 2009 Sep 15;125(6):1464-72. doi: 10.1002/ijc.24521.

15.

Diethyldithiocarbamate induces apoptosis in HHV-8-infected primary effusion lymphoma cells via inhibition of the NF-κB pathway.

Matsuno T, Kariya R, Yano S, Morino-Koga S, Taura M, Suico MA, Shimauchi Y, Matsuyama S, Okamoto Y, Shuto T, Kai H, Okada S.

Int J Oncol. 2012 Apr;40(4):1071-8. doi: 10.3892/ijo.2011.1313. Epub 2011 Dec 20.

16.

Histone deacetylase classes I and II regulate Kaposi's sarcoma-associated herpesvirus reactivation.

Shin HJ, DeCotiis J, Giron M, Palmeri D, Lukac DM.

J Virol. 2014 Jan;88(2):1281-92. doi: 10.1128/JVI.02665-13. Epub 2013 Nov 13.

17.

Synergistic interaction of the histone deacetylase inhibitor SAHA with the proteasome inhibitor bortezomib in mantle cell lymphoma.

Heider U, von Metzler I, Kaiser M, Rosche M, Sterz J, Rötzer S, Rademacher J, Jakob C, Fleissner C, Kuckelkorn U, Kloetzel PM, Sezer O.

Eur J Haematol. 2008 Feb;80(2):133-42. Epub 2007 Dec 20.

PMID:
18005386
18.

Cdk1 inhibition induces mutually inhibitory apoptosis and reactivation of Kaposi's sarcoma-associated herpesvirus.

Li X, Chen S, Sun R.

J Virol. 2012 Jun;86(12):6668-76. doi: 10.1128/JVI.06240-11. Epub 2012 Apr 11.

19.

Bortezomib and SAHA synergistically induce ROS-driven caspase-dependent apoptosis of nasopharyngeal carcinoma and block replication of Epstein-Barr virus.

Hui KF, Lam BH, Ho DN, Tsao SW, Chiang AK.

Mol Cancer Ther. 2013 May;12(5):747-58. doi: 10.1158/1535-7163.MCT-12-0811. Epub 2013 Mar 8.

20.

Targeting sphingosine kinase induces apoptosis and tumor regression for KSHV-associated primary effusion lymphoma.

Qin Z, Dai L, Trillo-Tinoco J, Senkal C, Wang W, Reske T, Bonstaff K, Del Valle L, Rodriguez P, Flemington E, Voelkel-Johnson C, Smith CD, Ogretmen B, Parsons C.

Mol Cancer Ther. 2014 Jan;13(1):154-64. doi: 10.1158/1535-7163.MCT-13-0466. Epub 2013 Oct 18.

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