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Results: 1 to 20 of 113

1.

Systems analysis of the NCI-60 cancer cell lines by alignment of protein pathway activation modules with "-OMIC" data fields and therapeutic response signatures.

Federici G, Gao X, Slawek J, Arodz T, Shitaye A, Wulfkuhle JD, De Maria R, Liotta LA, Petricoin EF 3rd.

Mol Cancer Res. 2013 Jun;11(6):676-85. doi: 10.1158/1541-7786.MCR-12-0690. Epub 2013 May 1.

PMID:
23635402
[PubMed - indexed for MEDLINE]
Free Article
2.

A pilot characterization of human lung NSCLC by protein pathway activation mapping.

Zupa A, Improta G, Silvestri A, Pin E, Deng J, Aieta M, Musto P, Nitti D, Mammano E, Liotta L, Belluco C, Wulfkuhle J, Petricoin E 3rd.

J Thorac Oncol. 2012 Dec;7(12):1755-66. doi: 10.1097/JTO.0b013e3182725fc7.

PMID:
23154546
[PubMed - indexed for MEDLINE]
3.

Evaluation of reverse phase protein array (RPPA)-based pathway-activation profiling in 84 non-small cell lung cancer (NSCLC) cell lines as platform for cancer proteomics and biomarker discovery.

Ummanni R, Mannsperger HA, Sonntag J, Oswald M, Sharma AK, König R, Korf U.

Biochim Biophys Acta. 2014 May;1844(5):950-9. doi: 10.1016/j.bbapap.2013.11.017. Epub 2013 Dec 19.

PMID:
24361481
[PubMed - indexed for MEDLINE]
Free Article
4.

Laser capture microdissection and protein microarray analysis of human non-small cell lung cancer: differential epidermal growth factor receptor (EGPR) phosphorylation events associated with mutated EGFR compared with wild type.

VanMeter AJ, Rodriguez AS, Bowman ED, Jen J, Harris CC, Deng J, Calvert VS, Silvestri A, Fredolini C, Chandhoke V, Petricoin EF 3rd, Liotta LA, Espina V.

Mol Cell Proteomics. 2008 Oct;7(10):1902-24. doi: 10.1074/mcp.M800204-MCP200. Epub 2008 Aug 6.

PMID:
18687633
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Proteomic signatures of epidermal growth factor receptor and survival signal pathways correspond to gefitinib sensitivity in head and neck cancer.

Pernas FG, Allen CT, Winters ME, Yan B, Friedman J, Dabir B, Saigal K, Mundinger GS, Xu X, Morris JC, Calvo KR, Van Waes C, Chen Z.

Clin Cancer Res. 2009 Apr 1;15(7):2361-72. doi: 10.1158/1078-0432.CCR-08-1011. Epub 2009 Mar 24.

PMID:
19318490
[PubMed - indexed for MEDLINE]
Free Article
6.

Tyrosine phosphorylation profiling reveals the signaling network characteristics of Basal breast cancer cells.

Hochgräfe F, Zhang L, O'Toole SA, Browne BC, Pinese M, Porta Cubas A, Lehrbach GM, Croucher DR, Rickwood D, Boulghourjian A, Shearer R, Nair R, Swarbrick A, Faratian D, Mullen P, Harrison DJ, Biankin AV, Sutherland RL, Raftery MJ, Daly RJ.

Cancer Res. 2010 Nov 15;70(22):9391-401. doi: 10.1158/0008-5472.CAN-10-0911. Epub 2010 Sep 21.

PMID:
20861192
[PubMed - indexed for MEDLINE]
Free Article
7.

Insulin-like growth factor-1 receptor inhibition induces a resistance mechanism via the epidermal growth factor receptor/HER3/AKT signaling pathway: rational basis for cotargeting insulin-like growth factor-1 receptor and epidermal growth factor receptor in hepatocellular carcinoma.

Desbois-Mouthon C, Baron A, Blivet-Van Eggelpoël MJ, Fartoux L, Venot C, Bladt F, Housset C, Rosmorduc O.

Clin Cancer Res. 2009 Sep 1;15(17):5445-56. doi: 10.1158/1078-0432.CCR-08-2980. Epub 2009 Aug 25.

PMID:
19706799
[PubMed - indexed for MEDLINE]
Free Article
8.

Identification of optimal drug combinations targeting cellular networks: integrating phospho-proteomics and computational network analysis.

Iadevaia S, Lu Y, Morales FC, Mills GB, Ram PT.

Cancer Res. 2010 Sep 1;70(17):6704-14. doi: 10.1158/0008-5472.CAN-10-0460. Epub 2010 Jul 19.

PMID:
20643779
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Protein pathway activation mapping of brain metastasis from lung and breast cancers reveals organ type specific drug target activation.

Improta G, Zupa A, Fillmore H, Deng J, Aieta M, Musto P, Liotta LA, Broaddus W, Petricoin EF 3rd, Wulfkuhle JD.

J Proteome Res. 2011 Jul 1;10(7):3089-97. doi: 10.1021/pr200065t. Epub 2011 May 27.

PMID:
21574647
[PubMed - indexed for MEDLINE]
10.

Integrative analysis of proteomic signatures, mutations, and drug responsiveness in the NCI 60 cancer cell line set.

Park ES, Rabinovsky R, Carey M, Hennessy BT, Agarwal R, Liu W, Ju Z, Deng W, Lu Y, Woo HG, Kim SB, Cheong JH, Garraway LA, Weinstein JN, Mills GB, Lee JS, Davies MA.

Mol Cancer Ther. 2010 Feb;9(2):257-67. doi: 10.1158/1535-7163.MCT-09-0743. Epub 2010 Feb 2.

PMID:
20124458
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Protein expression signatures for inhibition of epidermal growth factor receptor-mediated signaling.

Myers MV, Manning HC, Coffey RJ, Liebler DC.

Mol Cell Proteomics. 2012 Feb;11(2):M111.015222. doi: 10.1074/mcp.M111.015222. Epub 2011 Dec 5.

PMID:
22147731
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Chemoresistant tumor cell lines display altered epidermal growth factor receptor and HER3 signaling and enhanced sensitivity to gefitinib.

Servidei T, Riccardi A, Mozzetti S, Ferlini C, Riccardi R.

Int J Cancer. 2008 Dec 15;123(12):2939-49. doi: 10.1002/ijc.23902.

PMID:
18803287
[PubMed - indexed for MEDLINE]
13.

Cross-talk between epidermal growth factor receptor and hypoxia-inducible factor-1alpha signal pathways increases resistance to apoptosis by up-regulating survivin gene expression.

Peng XH, Karna P, Cao Z, Jiang BH, Zhou M, Yang L.

J Biol Chem. 2006 Sep 8;281(36):25903-14. Epub 2006 Jul 17.

PMID:
16847054
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Phosphotyrosine signaling networks in epidermal growth factor receptor overexpressing squamous carcinoma cells.

Thelemann A, Petti F, Griffin G, Iwata K, Hunt T, Settinari T, Fenyo D, Gibson N, Haley JD.

Mol Cell Proteomics. 2005 Apr;4(4):356-76. Epub 2005 Jan 17.

PMID:
15657067
[PubMed - indexed for MEDLINE]
Free Article
15.

Protein pathway biomarker analysis of human cancer reveals requirement for upfront cellular-enrichment processing.

Silvestri A, Colombatti A, Calvert VS, Deng J, Mammano E, Belluco C, De Marchi F, Nitti D, Liotta LA, Petricoin EF, Pierobon M.

Lab Invest. 2010 May;90(5):787-96. doi: 10.1038/labinvest.2010.47. Epub 2010 Mar 1.

PMID:
20195244
[PubMed - indexed for MEDLINE]
Free Article
16.

Interactions between the epidermal growth factor receptor and type I protein kinase A: biological significance and therapeutic implications.

Ciardiello F, Tortora G.

Clin Cancer Res. 1998 Apr;4(4):821-8. Review.

PMID:
9563874
[PubMed - indexed for MEDLINE]
Free Article
19.

Insulin receptor substrate-1 involvement in epidermal growth factor receptor and insulin-like growth factor receptor signalling: implication for Gefitinib ('Iressa') response and resistance.

Knowlden JM, Jones HE, Barrow D, Gee JM, Nicholson RI, Hutcheson IR.

Breast Cancer Res Treat. 2008 Sep;111(1):79-91. Epub 2007 Sep 28.

PMID:
17902048
[PubMed - indexed for MEDLINE]
20.

Epidermal growth factor receptor-dependent regulation of integrin-mediated signaling and cell cycle entry in epithelial cells.

Bill HM, Knudsen B, Moores SL, Muthuswamy SK, Rao VR, Brugge JS, Miranti CK.

Mol Cell Biol. 2004 Oct;24(19):8586-99.

PMID:
15367678
[PubMed - indexed for MEDLINE]
Free PMC Article

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