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Results: 1 to 20 of 103

1.

Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1.

Ramkissoon LA, Horowitz PM, Craig JM, Ramkissoon SH, Rich BE, Schumacher SE, McKenna A, Lawrence MS, Bergthold G, Brastianos PK, Tabak B, Ducar MD, Van Hummelen P, MacConaill LE, Pouissant-Young T, Cho YJ, Taha H, Mahmoud M, Bowers DC, Margraf L, Tabori U, Hawkins C, Packer RJ, Hill DA, Pomeroy SL, Eberhart CG, Dunn IF, Goumnerova L, Getz G, Chan JA, Santagata S, Hahn WC, Stiles CD, Ligon AH, Kieran MW, Beroukhim R, Ligon KL.

Proc Natl Acad Sci U S A. 2013 May 14;110(20):8188-93. doi: 10.1073/pnas.1300252110. Epub 2013 Apr 30.

PMID:
23633565
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas.

Zhang J, Wu G, Miller CP, Tatevossian RG, Dalton JD, Tang B, Orisme W, Punchihewa C, Parker M, Qaddoumi I, Boop FA, Lu C, Kandoth C, Ding L, Lee R, Huether R, Chen X, Hedlund E, Nagahawatte P, Rusch M, Boggs K, Cheng J, Becksfort J, Ma J, Song G, Li Y, Wei L, Wang J, Shurtleff S, Easton J, Zhao D, Fulton RS, Fulton LL, Dooling DJ, Vadodaria B, Mulder HL, Tang C, Ochoa K, Mullighan CG, Gajjar A, Kriwacki R, Sheer D, Gilbertson RJ, Mardis ER, Wilson RK, Downing JR, Baker SJ, Ellison DW; St. Jude Children’s Research Hospital–Washington University Pediatric Cancer Genome Project.

Nat Genet. 2013 Jun;45(6):602-12. doi: 10.1038/ng.2611. Epub 2013 Apr 14.

PMID:
23583981
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

New strategies in pediatric gliomas: molecular advances in pediatric low-grade gliomas as a model.

Raabe E, Kieran MW, Cohen KJ.

Clin Cancer Res. 2013 Sep 1;19(17):4553-8. doi: 10.1158/1078-0432.CCR-13-0662. Epub 2013 Jul 23.

PMID:
23881924
[PubMed - indexed for MEDLINE]
Free Article
4.

MYB upregulation and genetic aberrations in a subset of pediatric low-grade gliomas.

Tatevossian RG, Tang B, Dalton J, Forshew T, Lawson AR, Ma J, Neale G, Shurtleff SA, Bailey S, Gajjar A, Baker SJ, Sheer D, Ellison DW.

Acta Neuropathol. 2010 Dec;120(6):731-43. doi: 10.1007/s00401-010-0763-1. Epub 2010 Nov 3.

PMID:
21046410
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Detection of KIAA1549-BRAF fusion transcripts in formalin-fixed paraffin-embedded pediatric low-grade gliomas.

Tian Y, Rich BE, Vena N, Craig JM, Macconaill LE, Rajaram V, Goldman S, Taha H, Mahmoud M, Ozek M, Sav A, Longtine JA, Lindeman NI, Garraway LA, Ligon AH, Stiles CD, Santagata S, Chan JA, Kieran MW, Ligon KL.

J Mol Diagn. 2011 Nov;13(6):669-77. doi: 10.1016/j.jmoldx.2011.07.002. Epub 2011 Aug 30.

PMID:
21884820
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

IDH mutation and neuroglial developmental features define clinically distinct subclasses of lower grade diffuse astrocytic glioma.

Gorovets D, Kannan K, Shen R, Kastenhuber ER, Islamdoust N, Campos C, Pentsova E, Heguy A, Jhanwar SC, Mellinghoff IK, Chan TA, Huse JT.

Clin Cancer Res. 2012 May 1;18(9):2490-501. doi: 10.1158/1078-0432.CCR-11-2977. Epub 2012 Mar 13.

PMID:
22415316
[PubMed - indexed for MEDLINE]
Free Article
7.

Frequent BRAF gain in low-grade diffuse gliomas with 1p/19q loss.

Kim YH, Nonoguchi N, Paulus W, Brokinkel B, Keyvani K, Sure U, Wrede K, Mariani L, Giangaspero F, Tanaka Y, Nakazato Y, Vital A, Mittelbronn M, Perry A, Ohgaki H.

Brain Pathol. 2012 Nov;22(6):834-40. doi: 10.1111/j.1750-3639.2012.00601.x. Epub 2012 Jun 1.

PMID:
22568401
[PubMed - indexed for MEDLINE]
8.

Diagnostic application of high resolution single nucleotide polymorphism array analysis for children with brain tumors.

Roth JJ, Santi M, Rorke-Adams LB, Harding BN, Busse TM, Tooke LS, Biegel JA.

Cancer Genet. 2014 Apr;207(4):111-23. doi: 10.1016/j.cancergen.2014.03.002. Epub 2014 Mar 15.

PMID:
24767714
[PubMed - indexed for MEDLINE]
9.

Glioma stem cells are more aggressive in recurrent tumors with malignant progression than in the primary tumor, and both can be maintained long-term in vitro.

Huang Q, Zhang QB, Dong J, Wu YY, Shen YT, Zhao YD, Zhu YD, Diao Y, Wang AD, Lan Q.

BMC Cancer. 2008 Oct 22;8:304. doi: 10.1186/1471-2407-8-304.

PMID:
18940013
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Homozygous loss of ADAM3A revealed by genome-wide analysis of pediatric high-grade glioma and diffuse intrinsic pontine gliomas.

Barrow J, Adamowicz-Brice M, Cartmill M, MacArthur D, Lowe J, Robson K, Brundler MA, Walker DA, Coyle B, Grundy R.

Neuro Oncol. 2011 Feb;13(2):212-22. doi: 10.1093/neuonc/noq158. Epub 2010 Dec 7.

PMID:
21138945
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Integrated molecular genetic profiling of pediatric high-grade gliomas reveals key differences with the adult disease.

Paugh BS, Qu C, Jones C, Liu Z, Adamowicz-Brice M, Zhang J, Bax DA, Coyle B, Barrow J, Hargrave D, Lowe J, Gajjar A, Zhao W, Broniscer A, Ellison DW, Grundy RG, Baker SJ.

J Clin Oncol. 2010 Jun 20;28(18):3061-8. doi: 10.1200/JCO.2009.26.7252. Epub 2010 May 17.

PMID:
20479398
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Interplay among BRAF, p16, p53, and MIB1 in pediatric low-grade gliomas.

Horbinski C, Nikiforova MN, Hagenkord JM, Hamilton RL, Pollack IF.

Neuro Oncol. 2012 Jun;14(6):777-89. doi: 10.1093/neuonc/nos077. Epub 2012 Apr 5.

PMID:
22492957
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

BRAF alterations in primary glial and glioneuronal neoplasms of the central nervous system with identification of 2 novel KIAA1549:BRAF fusion variants.

Lin A, Rodriguez FJ, Karajannis MA, Williams SC, Legault G, Zagzag D, Burger PC, Allen JC, Eberhart CG, Bar EE.

J Neuropathol Exp Neurol. 2012 Jan;71(1):66-72. doi: 10.1097/NEN.0b013e31823f2cb0.

PMID:
22157620
[PubMed - indexed for MEDLINE]
14.

Mutations in SETD2 and genes affecting histone H3K36 methylation target hemispheric high-grade gliomas.

Fontebasso AM, Schwartzentruber J, Khuong-Quang DA, Liu XY, Sturm D, Korshunov A, Jones DT, Witt H, Kool M, Albrecht S, Fleming A, Hadjadj D, Busche S, Lepage P, Montpetit A, Staffa A, Gerges N, Zakrzewska M, Zakrzewski K, Liberski PP, Hauser P, Garami M, Klekner A, Bognar L, Zadeh G, Faury D, Pfister SM, Jabado N, Majewski J.

Acta Neuropathol. 2013 May;125(5):659-69. doi: 10.1007/s00401-013-1095-8. Epub 2013 Feb 16.

PMID:
23417712
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Alterations in the RB1 pathway in low-grade diffuse gliomas lacking common genetic alterations.

Kim YH, Lachuer J, Mittelbronn M, Paulus W, Brokinkel B, Keyvani K, Sure U, Wrede K, Nobusawa S, Nakazato Y, Tanaka Y, Vital A, Mariani L, Ohgaki H.

Brain Pathol. 2011 Nov;21(6):645-51. doi: 10.1111/j.1750-3639.2011.00492.x. Epub 2011 May 30.

PMID:
21470325
[PubMed - indexed for MEDLINE]
16.

KLF6, a putative tumor suppressor gene, is mutated in astrocytic gliomas.

Jeng YM, Hsu HC.

Int J Cancer. 2003 Jul 10;105(5):625-9.

PMID:
12740910
[PubMed - indexed for MEDLINE]
17.

Prevalence, clinico-pathological value, and co-occurrence of PDGFRA abnormalities in diffuse gliomas.

Alentorn A, Marie Y, Carpentier C, Boisselier B, Giry M, Labussière M, Mokhtari K, Hoang-Xuan K, Sanson M, Delattre JY, Idbaih A.

Neuro Oncol. 2012 Nov;14(11):1393-403. doi: 10.1093/neuonc/nos217. Epub 2012 Oct 16. Erratum in: Neuro Oncol. 2013 Mar;15(3):403.

PMID:
23074200
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Isocitrate dehydrogenase 1 R132H mutation is not detected in angiocentric glioma.

Raghunathan A, Olar A, Vogel H, Parker JR, Coventry SC, Debski R, Albarracin CT, Aldape KD, Cahill DP 3rd, Powell SZ, Fuller GN.

Ann Diagn Pathol. 2012 Aug;16(4):255-9. doi: 10.1016/j.anndiagpath.2011.11.003. Epub 2012 Mar 23.

PMID:
22445362
[PubMed - indexed for MEDLINE]
19.

TET2 promoter methylation in low-grade diffuse gliomas lacking IDH1/2 mutations.

Kim YH, Pierscianek D, Mittelbronn M, Vital A, Mariani L, Hasselblatt M, Ohgaki H.

J Clin Pathol. 2011 Oct;64(10):850-2. doi: 10.1136/jclinpath-2011-200133. Epub 2011 Jun 20.

PMID:
21690245
[PubMed - indexed for MEDLINE]
20.
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