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Results: 1 to 20 of 100

1.

Cord factor and peptidoglycan recapitulate the Th17-promoting adjuvant activity of mycobacteria through mincle/CARD9 signaling and the inflammasome.

Shenderov K, Barber DL, Mayer-Barber KD, Gurcha SS, Jankovic D, Feng CG, Oland S, Hieny S, Caspar P, Yamasaki S, Lin X, Ting JP, Trinchieri G, Besra GS, Cerundolo V, Sher A.

J Immunol. 2013 Jun 1;190(11):5722-30. doi: 10.4049/jimmunol.1203343. Epub 2013 Apr 29.

PMID:
23630357
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

The Mincle-activating adjuvant TDB induces MyD88-dependent Th1 and Th17 responses through IL-1R signaling.

Desel C, Werninghaus K, Ritter M, Jozefowski K, Wenzel J, Russkamp N, Schleicher U, Christensen D, Wirtz S, Kirschning C, Agger EM, Prazeres da Costa C, Lang R.

PLoS One. 2013;8(1):e53531. doi: 10.1371/journal.pone.0053531. Epub 2013 Jan 7.

PMID:
23308247
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

The mycobacterial cord factor adjuvant analogue trehalose-6,6'-dibehenate (TDB) activates the Nlrp3 inflammasome.

Schweneker K, Gorka O, Schweneker M, Poeck H, Tschopp J, Peschel C, Ruland J, Gross O.

Immunobiology. 2013 Apr;218(4):664-73. doi: 10.1016/j.imbio.2012.07.029. Epub 2012 Aug 7.

PMID:
22921586
[PubMed - indexed for MEDLINE]
4.

Mycobacterium abscessus activates the NLRP3 inflammasome via Dectin-1-Syk and p62/SQSTM1.

Lee HM, Yuk JM, Kim KH, Jang J, Kang G, Park JB, Son JW, Jo EK.

Immunol Cell Biol. 2012 Jul;90(6):601-10. doi: 10.1038/icb.2011.72. Epub 2011 Aug 30.

PMID:
21876553
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Cutting edge: Mincle is essential for recognition and adjuvanticity of the mycobacterial cord factor and its synthetic analog trehalose-dibehenate.

Schoenen H, Bodendorfer B, Hitchens K, Manzanero S, Werninghaus K, Nimmerjahn F, Agger EM, Stenger S, Andersen P, Ruland J, Brown GD, Wells C, Lang R.

J Immunol. 2010 Mar 15;184(6):2756-60. doi: 10.4049/jimmunol.0904013. Epub 2010 Feb 17.

PMID:
20164423
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Serum amyloid A activates the NLRP3 inflammasome and promotes Th17 allergic asthma in mice.

Ather JL, Ckless K, Martin R, Foley KL, Suratt BT, Boyson JE, Fitzgerald KA, Flavell RA, Eisenbarth SC, Poynter ME.

J Immunol. 2011 Jul 1;187(1):64-73. doi: 10.4049/jimmunol.1100500. Epub 2011 May 27.

PMID:
21622869
[PubMed - indexed for MEDLINE]
Free PMC Article
7.
8.

Interleukin-1 receptor but not Toll-like receptor 2 is essential for MyD88-dependent Th17 immunity to Coccidioides infection.

Hung CY, Jiménez-Alzate Mdel P, Gonzalez A, Wüthrich M, Klein BS, Cole GT.

Infect Immun. 2014 May;82(5):2106-14. doi: 10.1128/IAI.01579-13. Epub 2014 Mar 10.

PMID:
24614655
[PubMed - indexed for MEDLINE]
9.

Escherichia coli heat-labile enterotoxin promotes protective Th17 responses against infection by driving innate IL-1 and IL-23 production.

Brereton CF, Sutton CE, Ross PJ, Iwakura Y, Pizza M, Rappuoli R, Lavelle EC, Mills KH.

J Immunol. 2011 May 15;186(10):5896-906. doi: 10.4049/jimmunol.1003789. Epub 2011 Apr 13.

PMID:
21490151
[PubMed - indexed for MEDLINE]
Free Article
10.

Neutrophils Promote Mycobacterial Trehalose Dimycolate-Induced Lung Inflammation via the Mincle Pathway.

Lee WB, Kang JS, Yan JJ, Lee MS, Jeon BY, Cho SN, Kim YJ.

PLoS Pathog. 2012;8(4):e1002614. doi: 10.1371/journal.ppat.1002614. Epub 2012 Apr 5.

PMID:
22496642
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

TLR2/MyD88/NF-κB pathway, reactive oxygen species, potassium efflux activates NLRP3/ASC inflammasome during respiratory syncytial virus infection.

Segovia J, Sabbah A, Mgbemena V, Tsai SY, Chang TH, Berton MT, Morris IR, Allen IC, Ting JP, Bose S.

PLoS One. 2012;7(1):e29695. doi: 10.1371/journal.pone.0029695. Epub 2012 Jan 25.

PMID:
22295065
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1β via a noncanonical caspase-8 inflammasome.

Gringhuis SI, Kaptein TM, Wevers BA, Theelen B, van der Vlist M, Boekhout T, Geijtenbeek TB.

Nat Immunol. 2012 Jan 22;13(3):246-54. doi: 10.1038/ni.2222.

PMID:
22267217
[PubMed - indexed for MEDLINE]
13.

Mechanism of impaired NLRP3 inflammasome priming by monophosphoryl lipid A.

Embry CA, Franchi L, Nuñez G, Mitchell TC.

Sci Signal. 2011 May 3;4(171):ra28. doi: 10.1126/scisignal.2001486.

PMID:
21540455
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Alcohol-induced IL-1β in the brain is mediated by NLRP3/ASC inflammasome activation that amplifies neuroinflammation.

Lippai D, Bala S, Petrasek J, Csak T, Levin I, Kurt-Jones EA, Szabo G.

J Leukoc Biol. 2013 Jul;94(1):171-82. doi: 10.1189/jlb.1212659. Epub 2013 Apr 26.

PMID:
23625200
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

MyD88 is essential to sustain mTOR activation necessary to promote T helper 17 cell proliferation by linking IL-1 and IL-23 signaling.

Chang J, Burkett PR, Borges CM, Kuchroo VK, Turka LA, Chang CH.

Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2270-5. doi: 10.1073/pnas.1206048110. Epub 2013 Jan 22.

PMID:
23341605
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Flagellin induces antibody responses through a TLR5- and inflammasome-independent pathway.

López-Yglesias AH, Zhao X, Quarles EK, Lai MA, VandenBos T, Strong RK, Smith KD.

J Immunol. 2014 Feb 15;192(4):1587-96. doi: 10.4049/jimmunol.1301893. Epub 2014 Jan 17.

PMID:
24442437
[PubMed - indexed for MEDLINE]
17.

Serum amyloid A activates the NLRP3 inflammasome via P2X7 receptor and a cathepsin B-sensitive pathway.

Niemi K, Teirilä L, Lappalainen J, Rajamäki K, Baumann MH, Öörni K, Wolff H, Kovanen PT, Matikainen S, Eklund KK.

J Immunol. 2011 Jun 1;186(11):6119-28. doi: 10.4049/jimmunol.1002843. Epub 2011 Apr 20.

PMID:
21508263
[PubMed - indexed for MEDLINE]
Free Article
18.

Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17.

LeibundGut-Landmann S, Gross O, Robinson MJ, Osorio F, Slack EC, Tsoni SV, Schweighoffer E, Tybulewicz V, Brown GD, Ruland J, Reis e Sousa C.

Nat Immunol. 2007 Jun;8(6):630-8. Epub 2007 Apr 22.

PMID:
17450144
[PubMed - indexed for MEDLINE]
19.

Pepsin digest of wheat gliadin fraction increases production of IL-1β via TLR4/MyD88/TRIF/MAPK/NF-κB signaling pathway and an NLRP3 inflammasome activation.

Palová-Jelínková L, Dáňová K, Drašarová H, Dvořák M, Funda DP, Fundová P, Kotrbová-Kozak A, Černá M, Kamanová J, Martin SF, Freudenberg M, Tučková L.

PLoS One. 2013 Apr 29;8(4):e62426. doi: 10.1371/journal.pone.0062426. Print 2013.

PMID:
23658628
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Critical role of ASC inflammasomes and bacterial type IV secretion system in caspase-1 activation and host innate resistance to Brucella abortus infection.

Gomes MT, Campos PC, Oliveira FS, Corsetti PP, Bortoluci KR, Cunha LD, Zamboni DS, Oliveira SC.

J Immunol. 2013 Apr 1;190(7):3629-38. doi: 10.4049/jimmunol.1202817. Epub 2013 Mar 4.

PMID:
23460746
[PubMed - indexed for MEDLINE]
Free Article

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