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Items: 1 to 20 of 99


Let-7 represses Nr6a1 and a mid-gestation developmental program in adult fibroblasts.

Gurtan AM, Ravi A, Rahl PB, Bosson AD, JnBaptiste CK, Bhutkar A, Whittaker CA, Young RA, Sharp PA.

Genes Dev. 2013 Apr 15;27(8):941-54. doi: 10.1101/gad.215376.113.


Dicer deficiency reveals microRNAs predicted to control gene expression in the developing adrenal cortex.

Krill KT, Gurdziel K, Heaton JH, Simon DP, Hammer GD.

Mol Endocrinol. 2013 May;27(5):754-68. doi: 10.1210/me.2012-1331. Epub 2013 Mar 21.


Epstein-Barr virus EBNA1 protein regulates viral latency through effects on let-7 microRNA and dicer.

Mansouri S, Pan Q, Blencowe BJ, Claycomb JM, Frappier L.

J Virol. 2014 Oct;88(19):11166-77. doi: 10.1128/JVI.01785-14. Epub 2014 Jul 16.


In vivo structure-function analysis of human Dicer reveals directional processing of precursor miRNAs.

Gurtan AM, Lu V, Bhutkar A, Sharp PA.

RNA. 2012 Jun;18(6):1116-22. doi: 10.1261/rna.032680.112. Epub 2012 Apr 30.


Overexpression of dicer as a result of reduced let-7 MicroRNA levels contributes to increased cell proliferation of oral cancer cells.

Jakymiw A, Patel RS, Deming N, Bhattacharyya I, Shah P, Lamont RJ, Stewart CM, Cohen DM, Chan EK.

Genes Chromosomes Cancer. 2010 Jun;49(6):549-59. doi: 10.1002/gcc.20765.


Dose-dependent differential mRNA target selection and regulation by let-7a-7f and miR-17-92 cluster microRNAs.

Shu J, Xia Z, Li L, Liang ET, Slipek N, Shen D, Foo J, Subramanian S, Steer CJ.

RNA Biol. 2012 Oct;9(10):1275-87. doi: 10.4161/rna.21998. Epub 2012 Sep 20.


MicroRNAs are indispensable for reprogramming mouse embryonic fibroblasts into induced stem cell-like cells.

Kim BM, Thier MC, Oh S, Sherwood R, Kanellopoulou C, Edenhofer F, Choi MY.

PLoS One. 2012;7(6):e39239. doi: 10.1371/journal.pone.0039239. Epub 2012 Jun 21.


The regulatory mechanism of CCR7 gene expression and its involvement in the metastasis and progression of gastric cancer.

Wang WN, Chen Y, Zhang YD, Hu TH.

Tumour Biol. 2013 Jun;34(3):1865-71. doi: 10.1007/s13277-013-0728-9. Epub 2013 Mar 22.


The Hippo pathway effectors TAZ/YAP regulate dicer expression and microRNA biogenesis through Let-7.

Chaulk SG, Lattanzi VJ, Hiemer SE, Fahlman RP, Varelas X.

J Biol Chem. 2014 Jan 24;289(4):1886-91. doi: 10.1074/jbc.C113.529362. Epub 2013 Dec 9.


Embryonic stem cell microRNAs: defining factors in induced pluripotent (iPS) and cancer (CSC) stem cells?

Gunaratne PH.

Curr Stem Cell Res Ther. 2009 Sep;4(3):168-77. Review.


Dicer cooperates with p53 to suppress DNA damage and skin carcinogenesis in mice.

Lyle S, Hoover K, Colpan C, Zhu Z, Matijasevic Z, Jones SN.

PLoS One. 2014 Jun 30;9(6):e100920. doi: 10.1371/journal.pone.0100920. eCollection 2014.


Let-7b/c enhance the stability of a tissue-specific mRNA during mammalian organogenesis as part of a feedback loop involving KSRP.

Repetto E, Briata P, Kuziner N, Harfe BD, McManus MT, Gherzi R, Rosenfeld MG, Trabucchi M.

PLoS Genet. 2012;8(7):e1002823. doi: 10.1371/journal.pgen.1002823. Epub 2012 Jul 26.


MicroRNA Let-7a and dicer are important in the activation and implantation of delayed implanting mouse embryos.

Cheong AW, Pang RT, Liu WM, Kottawatta KS, Lee KF, Yeung WS.

Hum Reprod. 2014 Apr;29(4):750-62. doi: 10.1093/humrep/det462. Epub 2014 Jan 12.


Gene network and pathway analysis of mice with conditional ablation of Dicer in post-mitotic neurons.

Dorval V, Smith PY, Delay C, Calvo E, Planel E, Zommer N, Buée L, Hébert SS.

PLoS One. 2012;7(8):e44060. doi: 10.1371/journal.pone.0044060. Epub 2012 Aug 27.


DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs.

Fukuda T, Yamagata K, Fujiyama S, Matsumoto T, Koshida I, Yoshimura K, Mihara M, Naitou M, Endoh H, Nakamura T, Akimoto C, Yamamoto Y, Katagiri T, Foulds C, Takezawa S, Kitagawa H, Takeyama K, O'Malley BW, Kato S.

Nat Cell Biol. 2007 May;9(5):604-11. Epub 2007 Apr 15. Retraction in: Nat Cell Biol. 2014 Nov;16(11):1126.


Dysregulation of uterine signaling pathways in progesterone receptor-Cre knockout of dicer.

Hawkins SM, Andreu-Vieyra CV, Kim TH, Jeong JW, Hodgson MC, Chen R, Creighton CJ, Lydon JP, Gunaratne PH, DeMayo FJ, Matzuk MM.

Mol Endocrinol. 2012 Sep;26(9):1552-66. doi: 10.1210/me.2012-1042. Epub 2012 Jul 13.


Conserved microRNA pathway regulates developmental timing of retinal neurogenesis.

La Torre A, Georgi S, Reh TA.

Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):E2362-70. doi: 10.1073/pnas.1301837110. Epub 2013 Jun 10.


RNA-binding protein AUF1 represses Dicer expression.

Abdelmohsen K, Tominaga-Yamanaka K, Srikantan S, Yoon JH, Kang MJ, Gorospe M.

Nucleic Acids Res. 2012 Dec;40(22):11531-44. doi: 10.1093/nar/gks930. Epub 2012 Oct 11.


Competition for XPO5 binding between Dicer mRNA, pre-miRNA and viral RNA regulates human Dicer levels.

Bennasser Y, Chable-Bessia C, Triboulet R, Gibbings D, Gwizdek C, Dargemont C, Kremer EJ, Voinnet O, Benkirane M.

Nat Struct Mol Biol. 2011 Mar;18(3):323-7. doi: 10.1038/nsmb.1987. Epub 2011 Feb 6.


Canonical and alternate functions of the microRNA biogenesis machinery.

Chong MM, Zhang G, Cheloufi S, Neubert TA, Hannon GJ, Littman DR.

Genes Dev. 2010 Sep 1;24(17):1951-60. doi: 10.1101/gad.1953310. Epub 2010 Aug 16. Erratum in: Genes Dev. 2010 Oct 1;24(19):2228.

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