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Items: 1 to 20 of 97

1.

Ex vivo expansion of human outgrowth endothelial cells leads to IL-8-mediated replicative senescence and impaired vasoreparative function.

Medina RJ, O'Neill CL, O'Doherty TM, Chambers SE, Guduric-Fuchs J, Neisen J, Waugh DJ, Simpson DA, Stitt AW.

Stem Cells. 2013 Aug;31(8):1657-68. doi: 10.1002/stem.1414.

2.

SU5416 induces premature senescence in endothelial progenitor cells from patients with age-related macular degeneration.

Thill M, Berna MJ, Kunst F, Wege H, Strunnikova NV, Gordiyenko N, Grierson R, Richard G, Csaky KG.

Mol Vis. 2011 Jan 10;17:85-98.

3.

MicroRNA-10A* and MicroRNA-21 modulate endothelial progenitor cell senescence via suppressing high-mobility group A2.

Zhu S, Deng S, Ma Q, Zhang T, Jia C, Zhuo D, Yang F, Wei J, Wang L, Dykxhoorn DM, Hare JM, Goldschmidt-Clermont PJ, Dong C.

Circ Res. 2013 Jan 4;112(1):152-64. doi: 10.1161/CIRCRESAHA.112.280016. Epub 2012 Oct 16.

4.

Hypoxia inhibits cellular senescence to restore the therapeutic potential of old human endothelial progenitor cells via the hypoxia-inducible factor-1α-TWIST-p21 axis.

Lee SH, Lee JH, Yoo SY, Hur J, Kim HS, Kwon SM.

Arterioscler Thromb Vasc Biol. 2013 Oct;33(10):2407-14. doi: 10.1161/ATVBAHA.113.301931. Epub 2013 Aug 8.

5.

Mitogen stimulation cooperates with telomere shortening to activate DNA damage responses and senescence signaling.

Satyanarayana A, Greenberg RA, Schaetzlein S, Buer J, Masutomi K, Hahn WC, Zimmermann S, Martens U, Manns MP, Rudolph KL.

Mol Cell Biol. 2004 Jun;24(12):5459-74.

6.

Dose-dependent modulatory effects of insulin on glucose-induced endothelial senescence in vitro and in vivo: a relationship between telomeres and nitric oxide.

Matsui-Hirai H, Hayashi T, Yamamoto S, Ina K, Maeda M, Kotani H, Iguchi A, Ignarro LJ, Hattori Y.

J Pharmacol Exp Ther. 2011 Jun;337(3):591-9. doi: 10.1124/jpet.110.177584. Epub 2011 Feb 28.

7.

Regulation of ROS-independent ERK signaling rescues replicative cellular senescence in ex vivo expanded human c-kit-positive cardiac progenitor cells.

Choi SH, Jung SY, Yoo SY, Yoo SM, Kim da Y, Kang S, Baek SH, Kwon SM.

Int J Cardiol. 2013 Oct 25;169(1):73-82. doi: 10.1016/j.ijcard.2013.08.076. Epub 2013 Sep 9.

PMID:
24094550
8.

Postmitotic neurons develop a p21-dependent senescence-like phenotype driven by a DNA damage response.

Jurk D, Wang C, Miwa S, Maddick M, Korolchuk V, Tsolou A, Gonos ES, Thrasivoulou C, Saffrey MJ, Cameron K, von Zglinicki T.

Aging Cell. 2012 Dec;11(6):996-1004. doi: 10.1111/j.1474-9726.2012.00870.x. Epub 2012 Sep 12.

9.

Puerarin reduces endothelial progenitor cells senescence through augmentation of telomerase activity.

Zhu J, Wang X, Shang Y, Xie X, Zhang F, Chen J, Fu G.

Vascul Pharmacol. 2008 Aug-Sep;49(2-3):106-10. doi: 10.1016/j.vph.2008.07.002. Epub 2008 Jul 20.

PMID:
18692596
10.

Cell senescence: a challenge in cartilage engineering and regeneration.

Li J, Pei M.

Tissue Eng Part B Rev. 2012 Aug;18(4):270-87. doi: 10.1089/ten.TEB.2011.0583. Epub 2012 Feb 28. Review.

PMID:
22273114
11.

Role of endonuclease G in senescence-associated cell death of human endothelial cells.

Diener T, Neuhaus M, Koziel R, Micutkova L, Jansen-Dürr P.

Exp Gerontol. 2010 Aug;45(7-8):638-44. doi: 10.1016/j.exger.2010.03.002. Epub 2010 Mar 6.

PMID:
20211237
12.

CXCL8 enhances the angiogenic activity of umbilical cord blood-derived outgrowth endothelial cells in vitro.

Kimura T, Kohno H, Matsuoka Y, Murakami M, Nakatsuka R, Hase M, Yasuda K, Uemura Y, Sasaki Y, Fukuhara S, Sonoda Y.

Cell Biol Int. 2011 Mar;35(3):201-8. doi: 10.1042/CBI20090225.

PMID:
20958269
13.

Endothelial progenitor cells: from senescence to rejuvenation.

Goligorsky MS.

Semin Nephrol. 2014 Jul;34(4):365-73. doi: 10.1016/j.semnephrol.2014.06.003. Epub 2014 Jun 13. Review.

14.
15.

Interleukin-8 prevents oxidative stress-induced human endothelial cell senescence via telomerase activation.

Shen XH, Xu SJ, Jin CY, Ding F, Zhou YC, Fu GS.

Int Immunopharmacol. 2013 Jun;16(2):261-7. doi: 10.1016/j.intimp.2013.04.003. Epub 2013 Apr 15.

PMID:
23597430
16.

Efficient nonadhesive ex vivo expansion of early endothelial progenitor cells derived from CD34+ human cord blood fraction for effective therapeutic vascularization.

O E, Lee BH, Ahn HY, Shin JC, Kim HK, Kim M, Park IY, Park YG, Joe YA.

FASEB J. 2011 Jan;25(1):159-69. doi: 10.1096/fj.10-162040. Epub 2010 Sep 17.

17.

Ataxia telangiectasia mutated (ATM)-mediated DNA damage response in oxidative stress-induced vascular endothelial cell senescence.

Zhan H, Suzuki T, Aizawa K, Miyagawa K, Nagai R.

J Biol Chem. 2010 Sep 17;285(38):29662-70. doi: 10.1074/jbc.M110.125138. Epub 2010 Jul 16.

18.

HMG-CoA reductase inhibitors reduce senescence and increase proliferation of endothelial progenitor cells via regulation of cell cycle regulatory genes.

Assmus B, Urbich C, Aicher A, Hofmann WK, Haendeler J, Rössig L, Spyridopoulos I, Zeiher AM, Dimmeler S.

Circ Res. 2003 May 16;92(9):1049-55. Epub 2003 Apr 3.

19.

Stress-induced premature senescence mediated by a novel gene, SENEX, results in an anti-inflammatory phenotype in endothelial cells.

Coleman PR, Hahn CN, Grimshaw M, Lu Y, Li X, Brautigan PJ, Beck K, Stocker R, Vadas MA, Gamble JR.

Blood. 2010 Nov 11;116(19):4016-24. doi: 10.1182/blood-2009-11-252700. Epub 2010 Jul 27.

20.

Interferon-gamma induces cellular senescence through p53-dependent DNA damage signaling in human endothelial cells.

Kim KS, Kang KW, Seu YB, Baek SH, Kim JR.

Mech Ageing Dev. 2009 Mar;130(3):179-88. doi: 10.1016/j.mad.2008.11.004. Epub 2008 Nov 21.

PMID:
19071156
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