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Items: 1 to 20 of 537

1.

Alcohol-induced IL-1β in the brain is mediated by NLRP3/ASC inflammasome activation that amplifies neuroinflammation.

Lippai D, Bala S, Petrasek J, Csak T, Levin I, Kurt-Jones EA, Szabo G.

J Leukoc Biol. 2013 Jul;94(1):171-82. doi: 10.1189/jlb.1212659. Epub 2013 Apr 26.

2.

Both bone marrow-derived and non-bone marrow-derived cells contribute to AIM2 and NLRP3 inflammasome activation in a MyD88-dependent manner in dietary steatohepatitis.

Csak T, Pillai A, Ganz M, Lippai D, Petrasek J, Park JK, Kodys K, Dolganiuc A, Kurt-Jones EA, Szabo G.

Liver Int. 2014 Oct;34(9):1402-13. doi: 10.1111/liv.12537. Epub 2014 Apr 17.

3.

Serum amyloid A activates the NLRP3 inflammasome via P2X7 receptor and a cathepsin B-sensitive pathway.

Niemi K, Teirilä L, Lappalainen J, Rajamäki K, Baumann MH, Öörni K, Wolff H, Kovanen PT, Matikainen S, Eklund KK.

J Immunol. 2011 Jun 1;186(11):6119-28. doi: 10.4049/jimmunol.1002843. Epub 2011 Apr 20.

5.

The NLRP3/ASC inflammasome promotes T-cell-dependent immune complex glomerulonephritis by canonical and noncanonical mechanisms.

Andersen K, Eltrich N, Lichtnekert J, Anders HJ, Vielhauer V.

Kidney Int. 2014 Nov;86(5):965-78. doi: 10.1038/ki.2014.161. Epub 2014 May 7.

PMID:
24805106
6.

Chronic alcohol-induced microRNA-155 contributes to neuroinflammation in a TLR4-dependent manner in mice.

Lippai D, Bala S, Csak T, Kurt-Jones EA, Szabo G.

PLoS One. 2013 Aug 9;8(8):e70945. doi: 10.1371/journal.pone.0070945. eCollection 2013.

7.

TLR-induced PAI-2 expression suppresses IL-1β processing via increasing autophagy and NLRP3 degradation.

Chuang SY, Yang CH, Chou CC, Chiang YP, Chuang TH, Hsu LC.

Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):16079-84. doi: 10.1073/pnas.1306556110. Epub 2013 Sep 16.

8.

Reactive oxygen species activated NLRP3 inflammasomes prime environment-induced murine dry eye.

Zheng Q, Ren Y, Reinach PS, She Y, Xiao B, Hua S, Qu J, Chen W.

Exp Eye Res. 2014 Aug;125:1-8. doi: 10.1016/j.exer.2014.05.001. Epub 2014 May 14.

PMID:
24836981
9.

Doxorubicin and daunorubicin induce processing and release of interleukin-1β through activation of the NLRP3 inflammasome.

Sauter KA, Wood LJ, Wong J, Iordanov M, Magun BE.

Cancer Biol Ther. 2011 Jun 15;11(12):1008-16. Epub 2011 Jun 15.

10.

Aloe vera downregulates LPS-induced inflammatory cytokine production and expression of NLRP3 inflammasome in human macrophages.

Budai MM, Varga A, Milesz S, Tőzsér J, Benkő S.

Mol Immunol. 2013 Dec;56(4):471-9. doi: 10.1016/j.molimm.2013.05.005. Epub 2013 Aug 1.

PMID:
23911403
11.

NLRP3 inflammasome activation in D-galactosamine and lipopolysaccharide-induced acute liver failure: role of heme oxygenase-1.

Kim SJ, Lee SM.

Free Radic Biol Med. 2013 Dec;65:997-1004. doi: 10.1016/j.freeradbiomed.2013.08.178. Epub 2013 Aug 29.

PMID:
23994575
12.

IL-1 receptor antagonist ameliorates inflammasome-dependent alcoholic steatohepatitis in mice.

Petrasek J, Bala S, Csak T, Lippai D, Kodys K, Menashy V, Barrieau M, Min SY, Kurt-Jones EA, Szabo G.

J Clin Invest. 2012 Oct;122(10):3476-89. doi: 10.1172/JCI60777. Epub 2012 Sep 4. Review.

13.

Reactive oxygen species activated NLRP3 inflammasomes initiate inflammation in hyperosmolarity stressed human corneal epithelial cells and environment-induced dry eye patients.

Zheng Q, Ren Y, Reinach PS, Xiao B, Lu H, Zhu Y, Qu J, Chen W.

Exp Eye Res. 2015 May;134:133-40. doi: 10.1016/j.exer.2015.02.013. Epub 2015 Feb 18.

PMID:
25701684
14.

Caspase-1/ASC inflammasome-mediated activation of IL-1β-ROS-NF-κB pathway for control of Trypanosoma cruzi replication and survival is dispensable in NLRP3-/- macrophages.

Dey N, Sinha M, Gupta S, Gonzalez MN, Fang R, Endsley JJ, Luxon BA, Garg NJ.

PLoS One. 2014 Nov 5;9(11):e111539. doi: 10.1371/journal.pone.0111539. eCollection 2014.

15.

HMGB1 promotes the activation of NLRP3 and caspase-8 inflammasomes via NF-κB pathway in acute glaucoma.

Chi W, Chen H, Li F, Zhu Y, Yin W, Zhuo Y.

J Neuroinflammation. 2015 Jul 30;12:137. doi: 10.1186/s12974-015-0360-2.

16.

ASC/caspase-1/IL-1β signaling triggers inflammatory responses by promoting HMGB1 induction in liver ischemia/reperfusion injury.

Kamo N, Ke B, Ghaffari AA, Shen XD, Busuttil RW, Cheng G, Kupiec-Weglinski JW.

Hepatology. 2013 Jul;58(1):351-62. doi: 10.1002/hep.26320. Epub 2013 May 15.

17.

Mechanisms that lead to the regulation of NLRP3 inflammasome expression and activation in human dental pulp fibroblasts.

Zhang A, Wang P, Ma X, Yin X, Li J, Wang H, Jiang W, Jia Q, Ni L.

Mol Immunol. 2015 Aug;66(2):253-62. doi: 10.1016/j.molimm.2015.03.009. Epub 2015 Apr 2.

18.

High mobility group box 1/Toll-like receptor danger signaling increases brain neuroimmune activation in alcohol dependence.

Crews FT, Qin L, Sheedy D, Vetreno RP, Zou J.

Biol Psychiatry. 2013 Apr 1;73(7):602-12. doi: 10.1016/j.biopsych.2012.09.030. Epub 2012 Dec 1.

19.

TLR2/MyD88/NF-κB pathway, reactive oxygen species, potassium efflux activates NLRP3/ASC inflammasome during respiratory syncytial virus infection.

Segovia J, Sabbah A, Mgbemena V, Tsai SY, Chang TH, Berton MT, Morris IR, Allen IC, Ting JP, Bose S.

PLoS One. 2012;7(1):e29695. doi: 10.1371/journal.pone.0029695. Epub 2012 Jan 25.

20.

Caspase-8 as an Effector and Regulator of NLRP3 Inflammasome Signaling.

Antonopoulos C, Russo HM, El Sanadi C, Martin BN, Li X, Kaiser WJ, Mocarski ES, Dubyak GR.

J Biol Chem. 2015 Aug 14;290(33):20167-84. doi: 10.1074/jbc.M115.652321. Epub 2015 Jun 22.

PMID:
26100631
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