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Results: 1 to 20 of 80

1.

2'-Deoxythymidine adducts from the anti-HIV drug nevirapine.

Antunes AM, Wolf B, Oliveira MC, Beland FA, Marques MM.

Molecules. 2013 Apr 26;18(5):4955-71. doi: 10.3390/molecules18054955.

PMID:
23624649
[PubMed - indexed for MEDLINE]
Free Article
2.

Synthesis and characterization of DNA adducts from the HIV reverse transcriptase inhibitor nevirapine.

Antunes AM, Duarte MP, Santos PP, da Costa GG, Heinze TM, Beland FA, Marques MM.

Chem Res Toxicol. 2008 Jul;21(7):1443-56. doi: 10.1021/tx8000972. Epub 2008 Jul 3.

PMID:
18597499
[PubMed - indexed for MEDLINE]
3.

Amino acid adduct formation by the nevirapine metabolite, 12-hydroxynevirapine--a possible factor in nevirapine toxicity.

Antunes AM, Godinho AL, Martins IL, Justino GC, Beland FA, Marques MM.

Chem Res Toxicol. 2010 May 17;23(5):888-99. doi: 10.1021/tx900443z.

PMID:
20392079
[PubMed - indexed for MEDLINE]
4.

Protein adducts as prospective biomarkers of nevirapine toxicity.

Antunes AM, Godinho AL, Martins IL, Oliveira MC, Gomes RA, Coelho AV, Beland FA, Marques MM.

Chem Res Toxicol. 2010 Nov 15;23(11):1714-25. doi: 10.1021/tx100186t. Epub 2010 Sep 1.

PMID:
20809596
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Synthesis and oxidation of 2-hydroxynevirapine, a metabolite of the HIV reverse transcriptase inhibitor nevirapine.

Antunes AM, Novais DA, da Silva JL, Santos PP, Oliveira MC, Beland FA, Marques MM.

Org Biomol Chem. 2011 Oct 26;9(22):7822-35. doi: 10.1039/c1ob06052j. Epub 2011 Oct 3.

PMID:
21969039
[PubMed - indexed for MEDLINE]
6.

Oxidation of 2-hydroxynevirapine, a phenolic metabolite of the anti-HIV drug nevirapine: evidence for an unusual pyridine ring contraction.

Antunes AM, Sidarus M, Novais DA, Harjivan SG, Santos PP, Ferreira da Silva JL, Beland FA, Marques MM.

Molecules. 2012 Mar 5;17(3):2616-27. doi: 10.3390/molecules17032616.

PMID:
22391597
[PubMed - indexed for MEDLINE]
Free Article
7.

A dipyrido [2,3-b:3',2'-f]azepine analog of the HIV-1 reverse transcriptase inhibitor nevirapine.

Dyatkin AB, Brickwood JR, Proudfoot JR.

Bioorg Med Chem Lett. 1998 Aug 18;8(16):2169-72.

PMID:
9873507
[PubMed - indexed for MEDLINE]
8.

Stavudine, lamivudine and nevirapine combination therapy for treatment of HIV infection and AIDS in adults.

Siegfried NL, Van Deventer PJ, Mahomed FA, Rutherford GW.

Cochrane Database Syst Rev. 2006 Apr 19;(2):CD004535. Review.

PMID:
16625606
[PubMed - indexed for MEDLINE]
9.

Antiretrovirals for reducing the risk of mother-to-child transmission of HIV infection.

Volmink J, Siegfried NL, van der Merwe L, Brocklehurst P.

Cochrane Database Syst Rev. 2007 Jan 24;(1):CD003510. Review. Update in: Cochrane Database Syst Rev. 2011;(7):CD003510.

PMID:
17253490
[PubMed - indexed for MEDLINE]
10.

Antiretrovirals for reducing the risk of mother-to-child transmission of HIV infection.

Siegfried N, van der Merwe L, Brocklehurst P, Sint TT.

Cochrane Database Syst Rev. 2011 Jul 6;(7):CD003510. doi: 10.1002/14651858.CD003510.pub3. Review.

PMID:
21735394
[PubMed - indexed for MEDLINE]
11.

The N348I mutation at the connection subdomain of HIV-1 reverse transcriptase decreases binding to nevirapine.

Schuckmann MM, Marchand B, Hachiya A, Kodama EN, Kirby KA, Singh K, Sarafianos SG.

J Biol Chem. 2010 Dec 3;285(49):38700-9. doi: 10.1074/jbc.M110.153783. Epub 2010 Sep 27.

PMID:
20876531
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Efficacy and durability of nevirapine in antiretroviral drug näive patients.

Lange JM.

J Acquir Immune Defic Syndr. 2003 Sep;34 Suppl 1:S40-52.

PMID:
14562857
[PubMed - indexed for MEDLINE]
13.

Protein-mediated antagonism between HIV reverse transcriptase ligands nevirapine and MgATP.

Zheng X, Mueller GA, DeRose EF, London RE.

Biophys J. 2013 Jun 18;104(12):2695-705. doi: 10.1016/j.bpj.2013.04.015.

PMID:
23790378
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Emergence and persistence of minor drug-resistant HIV-1 variants in Ugandan women after nevirapine single-dose prophylaxis.

Hauser A, Mugenyi K, Kabasinguzi R, Kuecherer C, Harms G, Kunz A.

PLoS One. 2011;6(5):e20357. doi: 10.1371/journal.pone.0020357. Epub 2011 May 31.

PMID:
21655245
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

[Antiretroviral agent nevirapine: its pharmacological action and potential for clinical use].

Takeuchi S, Osugi T.

Nihon Yakurigaku Zasshi. 1999 Oct;114(4):205-11. Review. Japanese.

PMID:
10584233
[PubMed - indexed for MEDLINE]
16.

Identification of the K103N resistance mutation in Ugandan women receiving nevirapine to prevent HIV-1 vertical transmission.

Jackson JB, Becker-Pergola G, Guay LA, Musoke P, Mracna M, Fowler MG, Mofenson LM, Mirochnick M, Mmiro F, Eshleman SH.

AIDS. 2000 Jul 28;14(11):F111-5.

PMID:
10983633
[PubMed - indexed for MEDLINE]
17.

Randomized, open-label, comparative trial to evaluate the efficacy and safety of three antiretroviral drug combinations including two nucleoside analogues and nevirapine for previously untreated HIV-1 Infection: the OzCombo 2 study.

French M, Amin J, Roth N, Carr A, Law M, Emery S, Drummond F, Cooper D; OzCombo 2 investigators.

HIV Clin Trials. 2002 May-Jun;3(3):177-85. Erratum in: HIV Clin Trials 2002 Nov-Dec;3(6):following table of contents.

PMID:
12032876
[PubMed - indexed for MEDLINE]
18.

Quantifying the impact of nevirapine-based prophylaxis strategies to prevent mother-to-child transmission of HIV-1: a combined pharmacokinetic, pharmacodynamic, and viral dynamic analysis to predict clinical outcomes.

Frank M, von Kleist M, Kunz A, Harms G, Schütte C, Kloft C.

Antimicrob Agents Chemother. 2011 Dec;55(12):5529-40. doi: 10.1128/AAC.00741-11. Epub 2011 Sep 26.

PMID:
21947390
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Characterization of nevirapine (NVP) resistance mutations and HIV type 1 subtype in women from Abidjan (Côte d'Ivoire) after NVP single-dose prophylaxis of HIV type 1 mother-to-child transmission.

Toni TD, Masquelier B, Lazaro E, Dore-Mbami M, Ba-Gomis FO, Téa-Diop Y, Kouakou K, Diby J, Sia E, Soppi S, Essien S, Schrive MH, Pinson P, Chenal H, Fleury HJ.

AIDS Res Hum Retroviruses. 2005 Dec;21(12):1031-4.

PMID:
16379606
[PubMed - indexed for MEDLINE]
20.

Prevalence of resistance to nevirapine in mothers and children after single-dose exposure to prevent vertical transmission of HIV-1: a meta-analysis.

Arrivé E, Newell ML, Ekouevi DK, Chaix ML, Thiebaut R, Masquelier B, Leroy V, Perre PV, Rouzioux C, Dabis F; Ghent Group on HIV in Women and Children.

Int J Epidemiol. 2007 Oct;36(5):1009-21. Epub 2007 May 28. Review.

PMID:
17533166
[PubMed - indexed for MEDLINE]
Free Article

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