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Items: 1 to 20 of 139

1.

Inhibition of SAPK/JNK leads to enhanced IL-1-induced IL-6 synthesis in osteoblasts.

Kondo A, Otsuka T, Matsushima-Nishiwaki R, Kuroyanagi G, Mizutani J, Wada I, Kozawa O, Tokuda H.

Arch Biochem Biophys. 2013 Jul 15;535(2):227-33. doi: 10.1016/j.abb.2013.04.007. Epub 2013 Apr 24.

PMID:
23624146
2.

AMP-activated protein kinase inhibitor decreases prostaglandin F2α-stimulated interleukin-6 synthesis through p38 MAP kinase in osteoblasts.

Kondo A, Otsuka T, Kato K, Natsume H, Kuroyanagi G, Mizutani J, Ito Y, Matsushima-Nishiwaki R, Kozawa O, Tokuda H.

Int J Mol Med. 2012 Dec;30(6):1487-92. doi: 10.3892/ijmm.2012.1159. Epub 2012 Oct 15.

PMID:
23064268
3.

(-)-Epigallocatechin gallate amplifies interleukin-1-stimulated interleukin-6 synthesis in osteoblast-like MC3T3-E1 cells.

Kuroyanagi G, Otsuka T, Kondo A, Matsushima-Nishiwaki R, Mizutani J, Kozawa O, Tokuda H.

Biochimie. 2013 Oct;95(10):1933-8. doi: 10.1016/j.biochi.2013.07.001. Epub 2013 Jul 10.

PMID:
23851196
4.

Involvement of AMP-activated protein kinase in thrombin-stimulated interleukin 6 synthesis in osteoblasts.

Tokuda H, Kato K, Natsume H, Kondo A, Kuroyanagi G, Matsushima-Nishiwaki R, Ito Y, Otsuka T, Kozawa O.

J Mol Endocrinol. 2012 Jun 27;49(1):47-55. doi: 10.1530/JME-11-0165. Print 2012 Aug.

5.

AMP-activated protein kinase regulates PDGF-BB-stimulated interleukin-6 synthesis in osteoblasts: involvement of mitogen-activated protein kinases.

Kato K, Otsuka T, Kondo A, Matsushima-Nishiwaki R, Natsume H, Kozawa O, Tokuda H.

Life Sci. 2012 Jan 2;90(1-2):71-6. doi: 10.1016/j.lfs.2011.10.023. Epub 2011 Nov 9.

PMID:
22100508
6.

Negative regulation by p70 S6 kinase of FGF-2-stimulated VEGF release through stress-activated protein kinase/c-Jun N-terminal kinase in osteoblasts.

Takai S, Tokuda H, Hanai Y, Harada A, Yasuda E, Matsushima-Nishiwaki R, Kato H, Ogura S, Ohta T, Kozawa O.

J Bone Miner Res. 2007 Mar;22(3):337-46.

7.

Involvement of SAPK/JNK in prostaglandin E(1)-induced VEGF synthesis in osteoblast-like cells.

Kanno Y, Tokuda H, Nakajima K, Ishisaki A, Shibata T, Numata O, Kozawa O.

Mol Cell Endocrinol. 2004 May 31;220(1-2):89-95.

PMID:
15196703
8.
9.

AMPK limits IL-1-stimulated IL-6 synthesis in osteoblasts: involvement of IκB/NF-κB pathway.

Kato K, Tokuda H, Matsushima-Nishiwaki R, Natsume H, Kondo A, Ito Y, Kozawa O, Otsuka T.

Cell Signal. 2012 Aug;24(8):1706-12. doi: 10.1016/j.cellsig.2012.04.012. Epub 2012 Apr 25.

PMID:
22560875
10.

(-)-Epigallocatechin gallate reduces platelet-derived growth factor-BB-stimulated interleukin-6 synthesis in osteoblasts: suppression of SAPK/JNK.

Takai S, Matsushima-Nishiwaki R, Adachi S, Natsume H, Minamitani C, Mizutani J, Otsuka T, Tokuda H, Kozawa O.

Mediators Inflamm. 2008;2008:291808. doi: 10.1155/2008/291808. Epub 2009 Jan 12.

11.

SAPK/JNK plays a role in transforming growth factor-beta-induced VEGF synthesis in osteoblasts.

Kanno Y, Ishisaki A, Yoshida M, Tokuda H, Numata O, Kozawa O.

Horm Metab Res. 2005 Mar;37(3):140-5.

PMID:
15824967
12.

Rho-kinase regulates thrombin-stimulated interleukin-6 synthesis via p38 mitogen-activated protein kinase in osteoblasts.

Kato K, Otsuka T, Matsushima-Nishiwaki R, Natsume H, Kozawa O, Tokuda H.

Int J Mol Med. 2011 Oct;28(4):653-8. doi: 10.3892/ijmm.2011.747. Epub 2011 Jul 12.

PMID:
21750859
13.

Mechanisms of tumor necrosis factor-alpha-induced interleukin-6 synthesis in glioma cells.

Tanabe K, Matsushima-Nishiwaki R, Yamaguchi S, Iida H, Dohi S, Kozawa O.

J Neuroinflammation. 2010 Mar 6;7:16. doi: 10.1186/1742-2094-7-16.

14.

Involvement of stress-activated protein kinase/c-Jun N-terminal kinase in endothelin-1-induced heat shock protein 27 in osteoblasts.

Tokuda H, Niwa M, Ito H, Oiso Y, Kato K, Kozawa O.

Eur J Endocrinol. 2003 Sep;149(3):239-45.

15.

Involvement of AMP-activated protein kinase in TGF-β-stimulated VEGF synthesis in osteoblasts.

Mizutani J, Tokuda H, Matsushima-Nishiwaki R, Kato K, Kondo A, Natsume H, Kozawa O, Otsuka T.

Int J Mol Med. 2012 Apr;29(4):550-6. doi: 10.3892/ijmm.2012.893. Epub 2012 Jan 23.

16.

Involvement of stress-activated protein kinase (SAPK)/c-Jun N-terminal kinase (JNK) in prostaglandin F2alpha-induced heat shock protein 27 in osteoblasts.

Tokuda H, Niwa M, Ishisaki A, Nakajima K, Ito H, Kato K, Kozawa O.

Prostaglandins Leukot Essent Fatty Acids. 2004 May;70(5):441-7.

PMID:
15062846
17.

Function of Rho-kinase in prostaglandin D2-induced interleukin-6 synthesis in osteoblasts.

Tokuda H, Takai S, Matsushima-Nishiwaki R, Hanai Y, Adachi S, Minamitani C, Mizutani J, Otsuka T, Kozawa O.

Prostaglandins Leukot Essent Fatty Acids. 2008 Jul-Aug;79(1-2):41-6. doi: 10.1016/j.plefa.2008.07.004. Epub 2008 Sep 3.

PMID:
18771907
18.

(--)-epigallocatechin gallate enhances prostaglandin F2alpha-induced VEGF synthesis via upregulating SAPK/JNK activation in osteoblasts.

Tokuda H, Takai S, Matsushima-Nishiwaki R, Akamatsu S, Hanai Y, Hosoi T, Harada A, Ohta T, Kozawa O.

J Cell Biochem. 2007 Apr 1;100(5):1146-53.

PMID:
17031857
19.

AMP-activated protein kinase positively regulates FGF-2-stimulated VEGF synthesis in osteoblasts.

Kato K, Tokuda H, Adachi S, Matsushima-Nishiwaki R, Natsume H, Yamakawa K, Gu Y, Otsuka T, Kozawa O.

Biochem Biophys Res Commun. 2010 Sep 10;400(1):123-7. doi: 10.1016/j.bbrc.2010.08.024. Epub 2010 Aug 12.

PMID:
20708602
20.

Midazolam suppresses interleukin-1β-induced interleukin-6 release from rat glial cells.

Tanabe K, Kozawa O, Iida H.

J Neuroinflammation. 2011 Jun 17;8:68. doi: 10.1186/1742-2094-8-68.

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