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Items: 1 to 20 of 124

1.

Genetic deletion of microsomal prostaglandin E synthase-1 suppresses mouse mammary tumor growth and angiogenesis.

Howe LR, Subbaramaiah K, Kent CV, Zhou XK, Chang SH, Hla T, Jakobsson PJ, Hudis CA, Dannenberg AJ.

Prostaglandins Other Lipid Mediat. 2013 Oct;106:99-105. doi: 10.1016/j.prostaglandins.2013.04.002. Epub 2013 Apr 25.

2.

HER2/neu-induced mammary tumorigenesis and angiogenesis are reduced in cyclooxygenase-2 knockout mice.

Howe LR, Chang SH, Tolle KC, Dillon R, Young LJ, Cardiff RD, Newman RA, Yang P, Thaler HT, Muller WJ, Hudis C, Brown AM, Hla T, Subbaramaiah K, Dannenberg AJ.

Cancer Res. 2005 Nov 1;65(21):10113-9.

3.

Pharmacological inhibition of microsomal prostaglandin E synthase-1 suppresses epidermal growth factor receptor-mediated tumor growth and angiogenesis.

Finetti F, Terzuoli E, Bocci E, Coletta I, Polenzani L, Mangano G, Alisi MA, Cazzolla N, Giachetti A, Ziche M, Donnini S.

PLoS One. 2012;7(7):e40576. doi: 10.1371/journal.pone.0040576. Epub 2012 Jul 18.

4.

Microsomal prostaglandin E synthase-1 is involved in multiple steps of colon carcinogenesis.

Sasaki Y, Kamei D, Ishikawa Y, Ishii T, Uematsu S, Akira S, Murakami M, Hara S.

Oncogene. 2012 Jun 14;31(24):2943-52. doi: 10.1038/onc.2011.472. Epub 2011 Oct 10.

PMID:
21986945
5.

Roles of microsomal prostaglandin E synthase-1 in lung metastasis formation in prostate cancer RM9 cells.

Takahashi R, Amano H, Satoh T, Tabata K, Ikeda M, Kitasato H, Akira S, Iwamura M, Majima M.

Biomed Pharmacother. 2014 Feb;68(1):71-7. doi: 10.1016/j.biopha.2013.10.008. Epub 2013 Nov 8.

PMID:
24291175
6.

Genetic deletion of mPGES-1 suppresses intestinal tumorigenesis.

Nakanishi M, Montrose DC, Clark P, Nambiar PR, Belinsky GS, Claffey KP, Xu D, Rosenberg DW.

Cancer Res. 2008 May 1;68(9):3251-9. doi: 10.1158/0008-5472.CAN-07-6100.

7.

p130Cas as a new regulator of mammary epithelial cell proliferation, survival, and HER2-neu oncogene-dependent breast tumorigenesis.

Cabodi S, Tinnirello A, Di Stefano P, Bisarò B, Ambrosino E, Castellano I, Sapino A, Arisio R, Cavallo F, Forni G, Glukhova M, Silengo L, Altruda F, Turco E, Tarone G, Defilippi P.

Cancer Res. 2006 May 1;66(9):4672-80.

8.

HER-2/neu status is a determinant of mammary aromatase activity in vivo: evidence for a cyclooxygenase-2-dependent mechanism.

Subbaramaiah K, Howe LR, Port ER, Brogi E, Fishman J, Liu CH, Hla T, Hudis C, Dannenberg AJ.

Cancer Res. 2006 May 15;66(10):5504-11.

9.

Inducible microsomal prostaglandin E synthase is overexpressed in colorectal adenomas and cancer.

Yoshimatsu K, Golijanin D, Paty PB, Soslow RA, Jakobsson PJ, DeLellis RA, Subbaramaiah K, Dannenberg AJ.

Clin Cancer Res. 2001 Dec;7(12):3971-6.

10.

Haploinsufficiency for p190B RhoGAP inhibits MMTV-Neu tumor progression.

Heckman-Stoddard BM, Vargo-Gogola T, McHenry PR, Jiang V, Herrick MP, Hilsenbeck SG, Settleman J, Rosen JM.

Breast Cancer Res. 2009;11(4):R61. doi: 10.1186/bcr2352. Epub 2009 Aug 24.

11.

mPGES-1-expressing bone marrow-derived cells enhance tumor growth and angiogenesis in mice.

Kamata H, Hosono K, Suzuki T, Ogawa Y, Kubo H, Katoh H, Ito Y, Uematsu S, Akira S, Watanabe M, Majima M.

Biomed Pharmacother. 2010 Jul;64(6):409-16. doi: 10.1016/j.biopha.2010.01.017. Epub 2010 Feb 25.

PMID:
20452172
12.

Microsomal prostaglandin E synthase-1 inhibits PTEN and promotes experimental cholangiocarcinogenesis and tumor progression.

Lu D, Han C, Wu T.

Gastroenterology. 2011 Jun;140(7):2084-94. doi: 10.1053/j.gastro.2011.02.056. Epub 2011 Feb 24.

13.

Genetic deletion of mPGES-1 accelerates intestinal tumorigenesis in APC(Min/+) mice.

Elander N, Ungerbäck J, Olsson H, Uematsu S, Akira S, Söderkvist P.

Biochem Biophys Res Commun. 2008 Jul 18;372(1):249-53. doi: 10.1016/j.bbrc.2008.05.026. Epub 2008 May 15.

PMID:
18485889
15.

Combination chemoprevention of HER2/neu-induced breast cancer using a cyclooxygenase-2 inhibitor and a retinoid X receptor-selective retinoid.

Brown PH, Subbaramaiah K, Salmon AP, Baker R, Newman RA, Yang P, Zhou XK, Bissonnette RP, Dannenberg AJ, Howe LR.

Cancer Prev Res (Phila). 2008 Aug;1(3):208-14. doi: 10.1158/1940-6207.CAPR-08-0021.

16.

Microsomal prostaglandin E synthase-1 in both cancer cells and hosts contributes to tumour growth, invasion and metastasis.

Kamei D, Murakami M, Sasaki Y, Nakatani Y, Majima M, Ishikawa Y, Ishii T, Uematsu S, Akira S, Hara S, Kudo I.

Biochem J. 2009 Dec 23;425(2):361-71. doi: 10.1042/BJ20090045.

17.

Alcohol promotes mammary tumor development via the estrogen pathway in estrogen receptor alpha-negative HER2/neu mice.

Wong AW, Dunlap SM, Holcomb VB, Nunez NP.

Alcohol Clin Exp Res. 2012 Apr;36(4):577-87. doi: 10.1111/j.1530-0277.2011.01654.x. Epub 2011 Oct 7.

PMID:
21981381
18.

Potential role of microsomal prostaglandin E synthase-1 in tumorigenesis.

Kamei D, Murakami M, Nakatani Y, Ishikawa Y, Ishii T, Kudo I.

J Biol Chem. 2003 May 23;278(21):19396-405. Epub 2003 Mar 7.

20.

Attenuated transforming growth factor beta signaling promotes metastasis in a model of HER2 mammary carcinogenesis.

Novitskiy SV, Forrester E, Pickup MW, Gorska AE, Chytil A, Aakre M, Polosukhina D, Owens P, Yusupova DR, Zhao Z, Ye F, Shyr Y, Moses HL.

Breast Cancer Res. 2014 Oct 4;16(5):425. doi: 10.1186/s13058-014-0425-7.

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