Format
Sort by

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 141

1.

Glycogen synthase kinase 3 regulates expression of nuclear factor-erythroid-2 related transcription factor-1 (Nrf1) and inhibits pro-survival function of Nrf1.

Biswas M, Kwong EK, Park E, Nagra P, Chan JY.

Exp Cell Res. 2013 Aug 1;319(13):1922-31. doi: 10.1016/j.yexcr.2013.04.013. Epub 2013 Apr 23.

2.

The Fbw7 tumor suppressor regulates nuclear factor E2-related factor 1 transcription factor turnover through proteasome-mediated proteolysis.

Biswas M, Phan D, Watanabe M, Chan JY.

J Biol Chem. 2011 Nov 11;286(45):39282-9. doi: 10.1074/jbc.M111.253807. Epub 2011 Sep 27.

3.

Stringent Control of NFE2L3 (Nuclear Factor, Erythroid 2-Like 3; NRF3) Protein Degradation by FBW7 (F-box/WD Repeat-containing Protein 7) and Glycogen Synthase Kinase 3 (GSK3).

Kannan MB, Dodard-Friedman I, Blank V.

J Biol Chem. 2015 Oct 23;290(43):26292-302. doi: 10.1074/jbc.M115.666446. Epub 2015 Aug 25.

PMID:
26306035
4.

Regulation of GATA-binding protein 2 levels via ubiquitin-dependent degradation by Fbw7: involvement of cyclin B-cyclin-dependent kinase 1-mediated phosphorylation of THR176 in GATA-binding protein 2.

Nakajima T, Kitagawa K, Ohhata T, Sakai S, Uchida C, Shibata K, Minegishi N, Yumimoto K, Nakayama KI, Masumoto K, Katou F, Niida H, Kitagawa M.

J Biol Chem. 2015 Apr 17;290(16):10368-81. doi: 10.1074/jbc.M114.613018. Epub 2015 Feb 10.

5.

E3 ubiquitin ligase Fbw7 negatively regulates granulocytic differentiation by targeting G-CSFR for degradation.

Lochab S, Pal P, Kapoor I, Kanaujiya JK, Sanyal S, Behre G, Trivedi AK.

Biochim Biophys Acta. 2013 Dec;1833(12):2639-52. doi: 10.1016/j.bbamcr.2013.06.018. Epub 2013 Jun 29.

6.

The Fbw7/human CDC4 tumor suppressor targets proproliferative factor KLF5 for ubiquitination and degradation through multiple phosphodegron motifs.

Liu N, Li H, Li S, Shen M, Xiao N, Chen Y, Wang Y, Wang W, Wang R, Wang Q, Sun J, Wang P.

J Biol Chem. 2010 Jun 11;285(24):18858-67. doi: 10.1074/jbc.M109.099440. Epub 2010 Apr 13.

7.

Dual regulation of the transcriptional activity of Nrf1 by β-TrCP- and Hrd1-dependent degradation mechanisms.

Tsuchiya Y, Morita T, Kim M, Iemura S, Natsume T, Yamamoto M, Kobayashi A.

Mol Cell Biol. 2011 Nov;31(22):4500-12. doi: 10.1128/MCB.05663-11. Epub 2011 Sep 12.

9.

FBW7 regulates endothelial functions by targeting KLF2 for ubiquitination and degradation.

Wang R, Wang Y, Liu N, Ren C, Jiang C, Zhang K, Yu S, Chen Y, Tang H, Deng Q, Fu C, Wang Y, Li R, Liu M, Pan W, Wang P.

Cell Res. 2013 Jun;23(6):803-19. doi: 10.1038/cr.2013.42. Epub 2013 Mar 19.

10.

Competition of nuclear factor-erythroid 2 factors related transcription factor isoforms, Nrf1 and Nrf2, in antioxidant enzyme induction.

Chepelev NL, Zhang H, Liu H, McBride S, Seal AJ, Morgan TE, Finch CE, Willmore WG, Davies KJ, Forman HJ.

Redox Biol. 2013 Jan 19;1:183-9. doi: 10.1016/j.redox.2013.01.005. eCollection 2013.

11.

Fbw7 promotes ubiquitin-dependent degradation of c-Myb: involvement of GSK3-mediated phosphorylation of Thr-572 in mouse c-Myb.

Kitagawa K, Hiramatsu Y, Uchida C, Isobe T, Hattori T, Oda T, Shibata K, Nakamura S, Kikuchi A, Kitagawa M.

Oncogene. 2009 Jun 25;28(25):2393-405. doi: 10.1038/onc.2009.111. Epub 2009 May 4.

PMID:
19421138
12.
13.

The Fbw7 tumor suppressor targets KLF5 for ubiquitin-mediated degradation and suppresses breast cell proliferation.

Zhao D, Zheng HQ, Zhou Z, Chen C.

Cancer Res. 2010 Jun 1;70(11):4728-38. doi: 10.1158/0008-5472.CAN-10-0040. Epub 2010 May 18.

14.

GSK-3β regulates cell growth, migration, and angiogenesis via Fbw7 and USP28-dependent degradation of HIF-1α.

Flügel D, Görlach A, Kietzmann T.

Blood. 2012 Feb 2;119(5):1292-301. doi: 10.1182/blood-2011-08-375014. Epub 2011 Dec 5.

15.

The v-Jun point mutation allows c-Jun to escape GSK3-dependent recognition and destruction by the Fbw7 ubiquitin ligase.

Wei W, Jin J, Schlisio S, Harper JW, Kaelin WG Jr.

Cancer Cell. 2005 Jul;8(1):25-33.

16.

MCRS2 represses the transactivation activities of Nrf1.

Wu JL, Lin YS, Yang CC, Lin YJ, Wu SF, Lin YT, Huang CF.

BMC Cell Biol. 2009 Feb 2;10:9. doi: 10.1186/1471-2121-10-9.

17.
19.

Rictor Undergoes Glycogen Synthase Kinase 3 (GSK3)-dependent, FBXW7-mediated Ubiquitination and Proteasomal Degradation.

Koo J, Wu X, Mao Z, Khuri FR, Sun SY.

J Biol Chem. 2015 May 29;290(22):14120-9. doi: 10.1074/jbc.M114.633057. Epub 2015 Apr 20.

20.

Characterization of Nrf1b, a novel isoform of the nuclear factor-erythroid-2 related transcription factor-1 that activates antioxidant response element-regulated genes.

Kwong EK, Kim KM, Penalosa PJ, Chan JY.

PLoS One. 2012;7(10):e48404. doi: 10.1371/journal.pone.0048404. Epub 2012 Oct 29.

Items per page

Supplemental Content

Write to the Help Desk