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Items: 1 to 20 of 101


Histone deacetylase inhibitor enhances recovery after AKI.

Cianciolo Cosentino C, Skrypnyk NI, Brilli LL, Chiba T, Novitskaya T, Woods C, West J, Korotchenko VN, McDermott L, Day BW, Davidson AJ, Harris RC, de Caestecker MP, Hukriede NA.

J Am Soc Nephrol. 2013 May;24(6):943-53. doi: 10.1681/ASN.2012111055. Epub 2013 Apr 25.


A PTBA small molecule enhances recovery and reduces postinjury fibrosis after aristolochic acid-induced kidney injury.

Novitskaya T, McDermott L, Zhang KX, Chiba T, Paueksakon P, Hukriede NA, de Caestecker MP.

Am J Physiol Renal Physiol. 2014 Mar 1;306(5):F496-504. doi: 10.1152/ajprenal.00534.2013. Epub 2013 Dec 26.


Bardoxolone methyl (BARD) ameliorates ischemic AKI and increases expression of protective genes Nrf2, PPARγ, and HO-1.

Wu QQ, Wang Y, Senitko M, Meyer C, Wigley WC, Ferguson DA, Grossman E, Chen J, Zhou XJ, Hartono J, Winterberg P, Chen B, Agarwal A, Lu CY.

Am J Physiol Renal Physiol. 2011 May;300(5):F1180-92. doi: 10.1152/ajprenal.00353.2010. Epub 2011 Feb 2.


Role of matrix metalloproteinase-2 in recovery after tubular damage in acute kidney injury in mice.

Kaneko T, Shimizu A, Mii A, Fujita E, Fujino T, Kunugi S, Du X, Akimoto T, Tsuruoka S, Ohashi R, Masuda Y, Iino Y, Katayama Y, Fukuda Y.

Nephron Exp Nephrol. 2012;122(1-2):23-35. doi: 10.1159/000346569. Epub 2013 Mar 14.


Ischemia-reperfusion model of acute kidney injury and post injury fibrosis in mice.

Skrypnyk NI, Harris RC, de Caestecker MP.

J Vis Exp. 2013 Aug 9;(78). doi: 10.3791/50495.


Histone deacetylase modulates the proinflammatory and -fibrotic changes in tubulointerstitial injury.

Marumo T, Hishikawa K, Yoshikawa M, Hirahashi J, Kawachi S, Fujita T.

Am J Physiol Renal Physiol. 2010 Jan;298(1):F133-41. doi: 10.1152/ajprenal.00400.2009. Epub 2009 Nov 11.


Formoterol restores mitochondrial and renal function after ischemia-reperfusion injury.

Jesinkey SR, Funk JA, Stallons LJ, Wills LP, Megyesi JK, Beeson CC, Schnellmann RG.

J Am Soc Nephrol. 2014 Jun;25(6):1157-62. doi: 10.1681/ASN.2013090952. Epub 2014 Feb 7.


α2-Adrenoceptor agonist dexmedetomidine protects septic acute kidney injury through increasing BMP-7 and inhibiting HDAC2 and HDAC5.

Hsing CH, Lin CF, So E, Sun DP, Chen TC, Li CF, Yeh CH.

Am J Physiol Renal Physiol. 2012 Nov 15;303(10):F1443-53. doi: 10.1152/ajprenal.00143.2012. Epub 2012 Aug 29.


Development of high-content assays for kidney progenitor cell expansion in transgenic zebrafish.

Sanker S, Cirio MC, Vollmer LL, Goldberg ND, McDermott LA, Hukriede NA, Vogt A.

J Biomol Screen. 2013 Dec;18(10):1193-202. doi: 10.1177/1087057113495296. Epub 2013 Jul 5.


Deletion of the epidermal growth factor receptor in renal proximal tubule epithelial cells delays recovery from acute kidney injury.

Chen J, Chen JK, Harris RC.

Kidney Int. 2012 Jul;82(1):45-52. doi: 10.1038/ki.2012.43. Epub 2012 Mar 14.


Blockade of cysteine-rich protein 61 attenuates renal inflammation and fibrosis after ischemic kidney injury.

Lai CF, Lin SL, Chiang WC, Chen YM, Wu VC, Young GH, Ko WJ, Kuo ML, Tsai TJ, Wu KD.

Am J Physiol Renal Physiol. 2014 Sep 1;307(5):F581-92. doi: 10.1152/ajprenal.00670.2013. Epub 2014 Jun 11.


The p53 inhibitor pifithrin-α can stimulate fibrosis in a rat model of ischemic acute kidney injury.

Dagher PC, Mai EM, Hato T, Lee SY, Anderson MD, Karozos SC, Mang HE, Knipe NL, Plotkin Z, Sutton TA.

Am J Physiol Renal Physiol. 2012 Jan 15;302(2):F284-91. doi: 10.1152/ajprenal.00317.2011. Epub 2011 Nov 2.


T2 relaxation time and apparent diffusion coefficient for noninvasive assessment of renal pathology after acute kidney injury in mice: comparison with histopathology.

Hueper K, Rong S, Gutberlet M, Hartung D, Mengel M, Lu X, Haller H, Wacker F, Meier M, Gueler F.

Invest Radiol. 2013 Dec;48(12):834-42. doi: 10.1097/RLI.0b013e31829d0414.


Class I HDAC activity is required for renal protection and regeneration after acute kidney injury.

Tang J, Yan Y, Zhao TC, Gong R, Bayliss G, Yan H, Zhuang S.

Am J Physiol Renal Physiol. 2014 Aug 1;307(3):F303-16. doi: 10.1152/ajprenal.00102.2014. Epub 2014 May 7.


Blocking the class I histone deacetylase ameliorates renal fibrosis and inhibits renal fibroblast activation via modulating TGF-beta and EGFR signaling.

Liu N, He S, Ma L, Ponnusamy M, Tang J, Tolbert E, Bayliss G, Zhao TC, Yan H, Zhuang S.

PLoS One. 2013;8(1):e54001. doi: 10.1371/journal.pone.0054001. Epub 2013 Jan 16.


Cell Therapy Using Human Induced Pluripotent Stem Cell-Derived Renal Progenitors Ameliorates Acute Kidney Injury in Mice.

Toyohara T, Mae S, Sueta S, Inoue T, Yamagishi Y, Kawamoto T, Kasahara T, Hoshina A, Toyoda T, Tanaka H, Araoka T, Sato-Otsubo A, Takahashi K, Sato Y, Yamaji N, Ogawa S, Yamanaka S, Osafune K.

Stem Cells Transl Med. 2015 Sep;4(9):980-92. doi: 10.5966/sctm.2014-0219. Epub 2015 Jul 21.


Exocyst Sec10 protects renal tubule cells from injury by EGFR/MAPK activation and effects on endocytosis.

Fogelgren B, Zuo X, Buonato JM, Vasilyev A, Baek JI, Choi SY, Chacon-Heszele MF, Palmyre A, Polgar N, Drummond I, Park KM, Lazzara MJ, Lipschutz JH.

Am J Physiol Renal Physiol. 2014 Dec 15;307(12):F1334-41. doi: 10.1152/ajprenal.00032.2014. Epub 2014 Oct 8.


Autophagy in acute kidney injury and repair.

He L, Livingston MJ, Dong Z.

Nephron Clin Pract. 2014;127(1-4):56-60. doi: 10.1159/000363677. Epub 2014 Sep 24. Review.


Role of histone deacetylase activity in the developing lateral line neuromast of zebrafish larvae.

He Y, Mei H, Yu H, Sun S, Ni W, Li H.

Exp Mol Med. 2014 May 9;46:e94. doi: 10.1038/emm.2014.18.

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