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Items: 1 to 20 of 106

1.

Increased susceptibility of HIF-1α heterozygous-null mice to cardiovascular malformations associated with maternal diabetes.

Bohuslavova R, Skvorova L, Sedmera D, Semenza GL, Pavlinkova G.

J Mol Cell Cardiol. 2013 Jul;60:129-41. doi: 10.1016/j.yjmcc.2013.04.015. Epub 2013 Apr 22.

PMID:
23619295
2.

Cardiac malformations and alteration of TGFbeta signaling system in diabetic embryopathy.

Zhao Z.

Birth Defects Res B Dev Reprod Toxicol. 2010 Apr;89(2):97-105. doi: 10.1002/bdrb.20225.

PMID:
20127828
3.

Gene expression profiling of changes induced by maternal diabetes in the embryonic heart.

Bohuslavova R, Skvorova L, Cerychova R, Pavlinkova G.

Reprod Toxicol. 2015 Nov;57:147-56. doi: 10.1016/j.reprotox.2015.06.045. Epub 2015 Jun 11.

PMID:
26073000
4.
5.

Specific local cardiovascular changes of Nepsilon-(carboxymethyl)lysine, vascular endothelial growth factor, and Smad2 in the developing embryos coincide with maternal diabetes-induced congenital heart defects.

Roest PA, Molin DG, Schalkwijk CG, van Iperen L, Wentzel P, Eriksson UJ, Gittenberger-de Groot AC.

Diabetes. 2009 May;58(5):1222-8. doi: 10.2337/db07-1016. Epub 2009 Feb 2.

6.

Cardia bifida, defective heart development and abnormal neural crest migration in embryos lacking hypoxia-inducible factor-1alpha.

Compernolle V, Brusselmans K, Franco D, Moorman A, Dewerchin M, Collen D, Carmeliet P.

Cardiovasc Res. 2003 Dec 1;60(3):569-79.

7.

Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha.

Iyer NV, Kotch LE, Agani F, Leung SW, Laughner E, Wenger RH, Gassmann M, Gearhart JD, Lawler AM, Yu AY, Semenza GL.

Genes Dev. 1998 Jan 15;12(2):149-62.

8.

The essential role of Cited2, a negative regulator for HIF-1alpha, in heart development and neurulation.

Yin Z, Haynie J, Yang X, Han B, Kiatchoosakun S, Restivo J, Yuan S, Prabhakar NR, Herrup K, Conlon RA, Hoit BD, Watanabe M, Yang YC.

Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10488-93. Epub 2002 Jul 29.

9.

Impaired physiological responses to chronic hypoxia in mice partially deficient for hypoxia-inducible factor 1alpha.

Yu AY, Shimoda LA, Iyer NV, Huso DL, Sun X, McWilliams R, Beaty T, Sham JS, Wiener CM, Sylvester JT, Semenza GL.

J Clin Invest. 1999 Mar;103(5):691-6.

11.

Partial deficiency of HIF-1α stimulates pathological cardiac changes in streptozotocin-induced diabetic mice.

Bohuslavova R, Kolar F, Sedmera D, Skvorova L, Papousek F, Neckar J, Pavlinkova G.

BMC Endocr Disord. 2014 Feb 6;14:11. doi: 10.1186/1472-6823-14-11.

12.
13.

Epiblastic Cited2 deficiency results in cardiac phenotypic heterogeneity and provides a mechanism for haploinsufficiency.

MacDonald ST, Bamforth SD, Chen CM, Farthing CR, Franklyn A, Broadbent C, Schneider JE, Saga Y, Lewandoski M, Bhattacharya S.

Cardiovasc Res. 2008 Aug 1;79(3):448-57. doi: 10.1093/cvr/cvn101. Epub 2008 Apr 25.

14.

Ablation of Nkx2-5 at mid-embryonic stage results in premature lethality and cardiac malformation.

Terada R, Warren S, Lu JT, Chien KR, Wessels A, Kasahara H.

Cardiovasc Res. 2011 Jul 15;91(2):289-99. doi: 10.1093/cvr/cvr037. Epub 2011 Feb 1.

15.

Molecular and morphological characterization of neural tube defects in embryos of diabetic Swiss Albino mice.

Loh WT, Dheen ST, Jiang B, Kumar SD, Tay SS.

Histol Histopathol. 2011 Aug;26(8):965-78.

PMID:
21692030
16.

Differential gene expression profiles during embryonic heart development in diabetic mice pregnancy.

Vijaya M, Manikandan J, Parakalan R, Dheen ST, Kumar SD, Tay SS.

Gene. 2013 Mar 10;516(2):218-27. doi: 10.1016/j.gene.2012.12.071. Epub 2012 Dec 31.

PMID:
23287646
17.
18.

HIF-1alpha signaling upstream of NKX2.5 is required for cardiac development in Xenopus.

Nagao K, Taniyama Y, Kietzmann T, Doi T, Komuro I, Morishita R.

J Biol Chem. 2008 Apr 25;283(17):11841-9. doi: 10.1074/jbc.M702563200. Epub 2008 Feb 25.

19.

Essential role of developmentally activated hypoxia-inducible factor 1alpha for cardiac morphogenesis and function.

Krishnan J, Ahuja P, Bodenmann S, Knapik D, Perriard E, Krek W, Perriard JC.

Circ Res. 2008 Nov 7;103(10):1139-46. doi: 10.1161/01.RES.0000338613.89841.c1. Epub 2008 Oct 10.

20.

Krüppel-like factor 2 is required for normal mouse cardiac development.

Chiplunkar AR, Lung TK, Alhashem Y, Koppenhaver BA, Salloum FN, Kukreja RC, Haar JL, Lloyd JA.

PLoS One. 2013;8(2):e54891. doi: 10.1371/journal.pone.0054891. Epub 2013 Feb 14.

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