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Results: 1 to 20 of 107

1.

Mechanisms of thymus medulla development and function.

Anderson G, Baik S, Cowan JE, Holland AM, McCarthy NI, Nakamura K, Parnell SM, White AJ, Lane PJ, Jenkinson EJ, Jenkinson WE.

Curr Top Microbiol Immunol. 2014;373:19-47. doi: 10.1007/82_2013_320. Review.

PMID:
23612988
[PubMed - indexed for MEDLINE]
2.

Thymic commitment of regulatory T cells is a pathway of TCR-dependent selection that isolates repertoires undergoing positive or negative selection.

Coutinho A, Caramalho I, Seixas E, Demengeot J.

Curr Top Microbiol Immunol. 2005;293:43-71. Review.

PMID:
15981475
[PubMed - indexed for MEDLINE]
3.

Lymphotoxin signals from positively selected thymocytes regulate the terminal differentiation of medullary thymic epithelial cells.

White AJ, Nakamura K, Jenkinson WE, Saini M, Sinclair C, Seddon B, Narendran P, Pfeffer K, Nitta T, Takahama Y, Caamano JH, Lane PJ, Jenkinson EJ, Anderson G.

J Immunol. 2010 Oct 15;185(8):4769-76. doi: 10.4049/jimmunol.1002151. Epub 2010 Sep 22.

PMID:
20861360
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Differentiation of regulatory Foxp3+ T cells in the thymic cortex.

Liston A, Nutsch KM, Farr AG, Lund JM, Rasmussen JP, Koni PA, Rudensky AY.

Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11903-8. doi: 10.1073/pnas.0801506105. Epub 2008 Aug 11.

PMID:
18695219
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Development and function of cortical thymic epithelial cells.

Takada K, Ohigashi I, Kasai M, Nakase H, Takahama Y.

Curr Top Microbiol Immunol. 2014;373:1-17. doi: 10.1007/82_2013_322. Review.

PMID:
23612989
[PubMed - indexed for MEDLINE]
6.

The thymic medulla is required for Foxp3+ regulatory but not conventional CD4+ thymocyte development.

Cowan JE, Parnell SM, Nakamura K, Caamano JH, Lane PJ, Jenkinson EJ, Jenkinson WE, Anderson G.

J Exp Med. 2013 Apr 8;210(4):675-81. doi: 10.1084/jem.20122070. Epub 2013 Mar 25.

PMID:
23530124
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Generating intrathymic microenvironments to establish T-cell tolerance.

Anderson G, Lane PJ, Jenkinson EJ.

Nat Rev Immunol. 2007 Dec;7(12):954-63. Review.

PMID:
17992179
[PubMed - indexed for MEDLINE]
8.

Epithelial and dendritic cells in the thymic medulla promote CD4+Foxp3+ regulatory T cell development via the CD27-CD70 pathway.

Coquet JM, Ribot JC, Bąbała N, Middendorp S, van der Horst G, Xiao Y, Neves JF, Fonseca-Pereira D, Jacobs H, Pennington DJ, Silva-Santos B, Borst J.

J Exp Med. 2013 Apr 8;210(4):715-28. doi: 10.1084/jem.20112061. Epub 2013 Apr 1.

PMID:
23547099
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Effects of RANKL on the thymic medulla.

Ohigashi I, Nitta T, Lkhagvasuren E, Yasuda H, Takahama Y.

Eur J Immunol. 2011 Jul;41(7):1822-7. doi: 10.1002/eji.201141480.

PMID:
21706487
[PubMed - indexed for MEDLINE]
10.

Absence of thymus crosstalk in the fetus does not preclude hematopoietic induction of a functional thymus in the adult.

Roberts NA, Desanti GE, Withers DR, Scott HR, Jenkinson WE, Lane PJ, Jenkinson EJ, Anderson G.

Eur J Immunol. 2009 Sep;39(9):2395-402. doi: 10.1002/eji.200939501.

PMID:
19662637
[PubMed - indexed for MEDLINE]
11.

An essential role for medullary thymic epithelial cells during the intrathymic development of invariant NKT cells.

White AJ, Jenkinson WE, Cowan JE, Parnell SM, Bacon A, Jones ND, Jenkinson EJ, Anderson G.

J Immunol. 2014 Mar 15;192(6):2659-66. doi: 10.4049/jimmunol.1303057. Epub 2014 Feb 7.

PMID:
24510964
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Thymic epithelial cells: working class heroes for T cell development and repertoire selection.

Anderson G, Takahama Y.

Trends Immunol. 2012 Jun;33(6):256-63. doi: 10.1016/j.it.2012.03.005. Epub 2012 May 14. Review.

PMID:
22591984
[PubMed - indexed for MEDLINE]
13.

Serial progression of cortical and medullary thymic epithelial microenvironments.

Alves NL, Takahama Y, Ohigashi I, Ribeiro AR, Baik S, Anderson G, Jenkinson WE.

Eur J Immunol. 2014 Jan;44(1):16-22. doi: 10.1002/eji.201344110. Epub 2013 Dec 4. Review.

PMID:
24214487
[PubMed - indexed for MEDLINE]
14.

Immunohistology of T cell differentiation in the thymus of H-Y-specific T cell receptor alpha/beta transgenic mice.

Van Ewijk W, Kisielow P, Von Boehmer H.

Eur J Immunol. 1990 Jan;20(1):129-37.

PMID:
1968388
[PubMed - indexed for MEDLINE]
15.

Manipulating thymic apoptosis for future therapy of autoimmune diseases.

Delfino DV, Pozzesi N, Pierangeli S, Ayroldi E, Fierabracci A.

Curr Pharm Des. 2011;17(29):3108-19. Review.

PMID:
21864269
[PubMed - indexed for MEDLINE]
16.

Thymic epithelial cells: antigen presenting cells that regulate T cell repertoire and tolerance development.

Alexandropoulos K, Danzl NM.

Immunol Res. 2012 Dec;54(1-3):177-90. doi: 10.1007/s12026-012-8301-y. Review.

PMID:
22454100
[PubMed - indexed for MEDLINE]
17.

Selection of Foxp3+ regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cells.

Aschenbrenner K, D'Cruz LM, Vollmann EH, Hinterberger M, Emmerich J, Swee LK, Rolink A, Klein L.

Nat Immunol. 2007 Apr;8(4):351-8. Epub 2007 Feb 25.

PMID:
17322887
[PubMed - indexed for MEDLINE]
18.

Analysis of APC types involved in CD4 tolerance and regulatory T cell generation using reaggregated thymic organ cultures.

Guerri L, Peguillet I, Geraldo Y, Nabti S, Premel V, Lantz O.

J Immunol. 2013 Mar 1;190(5):2102-10. doi: 10.4049/jimmunol.1202883. Epub 2013 Jan 30.

PMID:
23365074
[PubMed - indexed for MEDLINE]
Free Article
19.

Ltbetar signaling does not regulate Aire-dependent transcripts in medullary thymic epithelial cells.

Martins VC, Boehm T, Bleul CC.

J Immunol. 2008 Jul 1;181(1):400-7.

PMID:
18566406
[PubMed - indexed for MEDLINE]
Free Article
20.

Delayed functional maturation of natural regulatory T cells in the medulla of postnatal thymus: role of TSLP.

Jiang Q, Su H, Knudsen G, Helms W, Su L.

BMC Immunol. 2006 Apr 3;7:6.

PMID:
16579866
[PubMed - indexed for MEDLINE]
Free PMC Article

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