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1.

TREM-2 promotes host resistance against Pseudomonas aeruginosa infection by suppressing corneal inflammation via a PI3K/Akt signaling pathway.

Sun M, Zhu M, Chen K, Nie X, Deng Q, Hazlett LD, Wu Y, Li M, Wu M, Huang X.

Invest Ophthalmol Vis Sci. 2013 May 17;54(5):3451-62. doi: 10.1167/iovs.12-10938.

2.

TREM-1 amplifies corneal inflammation after Pseudomonas aeruginosa infection by modulating Toll-like receptor signaling and Th1/Th2-type immune responses.

Wu M, Peng A, Sun M, Deng Q, Hazlett LD, Yuan J, Liu X, Gao Q, Feng L, He J, Zhang P, Huang X.

Infect Immun. 2011 Jul;79(7):2709-16. doi: 10.1128/IAI.00144-11. Epub 2011 May 9.

3.

ST2 is essential for Th2 responsiveness and resistance to pseudomonas aeruginosa keratitis.

Huang X, Du W, Barrett RP, Hazlett LD.

Invest Ophthalmol Vis Sci. 2007 Oct;48(10):4626-33.

PMID:
17898286
4.

TREM-2 promotes macrophage-mediated eradication of Pseudomonas aeruginosa via a PI3K/Akt pathway.

Zhu M, Li D, Wu Y, Huang X, Wu M.

Scand J Immunol. 2014 Mar;79(3):187-96. doi: 10.1111/sji.12148.

PMID:
24383713
5.

Lithium chloride promotes host resistance against Pseudomonas aeruginosa keratitis.

Chen K, Wu Y, Zhu M, Deng Q, Nie X, Li M, Wu M, Huang X.

Mol Vis. 2013 Jul 19;19:1502-14. Print 2013.

6.

TLR4 is required for host resistance in Pseudomonas aeruginosa keratitis.

Huang X, Du W, McClellan SA, Barrett RP, Hazlett LD.

Invest Ophthalmol Vis Sci. 2006 Nov;47(11):4910-6.

PMID:
17065506
7.

Silencing Toll-like receptor-9 in Pseudomonas aeruginosa keratitis.

Huang X, Barrett RP, McClellan SA, Hazlett LD.

Invest Ophthalmol Vis Sci. 2005 Nov;46(11):4209-16.

PMID:
16249500
8.

IL-33 shifts macrophage polarization, promoting resistance against Pseudomonas aeruginosa keratitis.

Hazlett LD, McClellan SA, Barrett RP, Huang X, Zhang Y, Wu M, van Rooijen N, Szliter E.

Invest Ophthalmol Vis Sci. 2010 Mar;51(3):1524-32. doi: 10.1167/iovs.09-3983. Epub 2009 Nov 5.

9.

Role of the Fas pathway in Pseudomonas aeruginosa keratitis.

Zhou Z, Wu M, Barrett RP, McClellan SA, Zhang Y, Hazlett LD.

Invest Ophthalmol Vis Sci. 2010 May;51(5):2537-47. doi: 10.1167/iovs.09-4152. Epub 2009 Dec 17.

10.

MRP8/14 enhances corneal susceptibility to Pseudomonas aeruginosa Infection by amplifying inflammatory responses.

Deng Q, Sun M, Yang K, Zhu M, Chen K, Yuan J, Wu M, Huang X.

Invest Ophthalmol Vis Sci. 2013 Feb 1;54(2):1227-34. doi: 10.1167/iovs.12-10172.

11.

Testican-1 promotes resistance against Pseudomonas aeruginosa-induced keratitis through regulation of MMP-2 expression and activation.

Berger EA, McClellan SA, Barrett RP, Hazlett LD.

Invest Ophthalmol Vis Sci. 2011 Jul 18;52(8):5339-46. doi: 10.1167/iovs.10-6920.

12.
13.

Beta-defensin-2 promotes resistance against infection with P. aeruginosa.

Wu M, McClellan SA, Barrett RP, Hazlett LD.

J Immunol. 2009 Feb 1;182(3):1609-16.

14.
15.

Substance P promotes susceptibility to Pseudomonas aeruginosa keratitis in resistant mice: anti-inflammatory mediators downregulated.

McClellan SA, Zhang Y, Barrett RP, Hazlett LD.

Invest Ophthalmol Vis Sci. 2008 Apr;49(4):1502-11. doi: 10.1167/iovs.07-1369.

PMID:
18385069
16.

Interferon regulatory factor-1 in flagellin-induced reprogramming: potential protective role of CXCL10 in cornea innate defense against Pseudomonas aeruginosa infection.

Yoon GS, Dong C, Gao N, Kumar A, Standiford TJ, Yu FS.

Invest Ophthalmol Vis Sci. 2013 Nov 15;54(12):7510-21. doi: 10.1167/iovs.13-12453.

17.

Interleukin 17 regulates Mer tyrosine kinase-positive cells in Pseudomonas aeruginosa keratitis.

Li C, McClellan SA, Barrett R, Hazlett LD.

Invest Ophthalmol Vis Sci. 2014 Oct 8;55(10):6886-900. doi: 10.1167/iovs.14-14522.

18.

HGF signaling impacts severity of Pseudomonas aeruginosa keratitis.

Jiang X, McClellan SA, Barrett R, Foldenauer M, Hazlett LD.

Invest Ophthalmol Vis Sci. 2014 Apr 9;55(4):2180-90. doi: 10.1167/iovs.13-13743.

19.

β-Catenin promotes host resistance against Pseudomonas aeruginosa keratitis.

Chen K, Yin L, Nie X, Deng Q, Wu Y, Zhu M, Li D, Li M, Wu M, Huang X.

J Infect. 2013 Dec;67(6):584-94. doi: 10.1016/j.jinf.2013.07.025. Epub 2013 Jul 31.

PMID:
23911965
20.

Cathelicidin-deficient (Cnlp -/- ) mice show increased susceptibility to Pseudomonas aeruginosa keratitis.

Huang LC, Reins RY, Gallo RL, McDermott AM.

Invest Ophthalmol Vis Sci. 2007 Oct;48(10):4498-508.

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