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Results: 1 to 20 of 113

1.

Microphthalmia transcription factor regulates pancreatic β-cell function.

Mazur MA, Winkler M, Ganic E, Colberg JK, Johansson JK, Bennet H, Fex M, Nuber UA, Artner I.

Diabetes. 2013 Aug;62(8):2834-42. doi: 10.2337/db12-1464. Epub 2013 Apr 22.

PMID:
23610061
[PubMed - indexed for MEDLINE]
Free Article
2.

Pax6 is crucial for β-cell function, insulin biosynthesis, and glucose-induced insulin secretion.

Gosmain Y, Katz LS, Masson MH, Cheyssac C, Poisson C, Philippe J.

Mol Endocrinol. 2012 Apr;26(4):696-709. doi: 10.1210/me.2011-1256. Epub 2012 Mar 8.

PMID:
22403172
[PubMed - indexed for MEDLINE]
3.

A regulatory loop involving PAX6, MITF, and WNT signaling controls retinal pigment epithelium development.

Bharti K, Gasper M, Ou J, Brucato M, Clore-Gronenborn K, Pickel J, Arnheiter H.

PLoS Genet. 2012 Jul;8(7):e1002757. doi: 10.1371/journal.pgen.1002757. Epub 2012 Jul 5.

PMID:
22792072
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Adult pancreatic islets require differential pax6 gene dosage.

Hamasaki A, Yamada Y, Kurose T, Ban N, Nagashima K, Takahashi A, Fujimoto S, Shimono D, Fujiwara M, Toyokuni S, Seino Y, Inagaki N.

Biochem Biophys Res Commun. 2007 Feb 2;353(1):40-6. Epub 2006 Dec 4.

PMID:
17178107
[PubMed - indexed for MEDLINE]
5.

The developmental regulator Pax6 is essential for maintenance of islet cell function in the adult mouse pancreas.

Hart AW, Mella S, Mendrychowski J, van Heyningen V, Kleinjan DA.

PLoS One. 2013;8(1):e54173. doi: 10.1371/journal.pone.0054173. Epub 2013 Jan 11.

PMID:
23326594
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Pax6 controls the expression of critical genes involved in pancreatic {alpha} cell differentiation and function.

Gosmain Y, Marthinet E, Cheyssac C, Guérardel A, Mamin A, Katz LS, Bouzakri K, Philippe J.

J Biol Chem. 2010 Oct 22;285(43):33381-93. doi: 10.1074/jbc.M110.147215. Epub 2010 Jun 30.

PMID:
20592023
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

In vitro effects of mycophenolic acid on survival, function, and gene expression of pancreatic beta-cells.

Gallo R, Natale M, Vendrame F, Boggi U, Filipponi F, Marchetti P, Laghi Pasini F, Dotta F.

Acta Diabetol. 2012 Dec;49 Suppl 1:S123-31. doi: 10.1007/s00592-011-0368-8. Epub 2012 Jan 17.

PMID:
22249339
[PubMed - indexed for MEDLINE]
8.

Mitf functions as an in ovo regulator for cell differentiation and proliferation during development of the chick RPE.

Tsukiji N, Nishihara D, Yajima I, Takeda K, Shibahara S, Yamamoto H.

Dev Biol. 2009 Feb 15;326(2):335-46. doi: 10.1016/j.ydbio.2008.11.029. Epub 2008 Dec 7.

PMID:
19100253
[PubMed - indexed for MEDLINE]
Free Article
9.

A common variant upstream of the PAX6 gene influences islet function in man.

Ahlqvist E, Turrini F, Lang ST, Taneera J, Zhou Y, Almgren P, Hansson O, Isomaa B, Tuomi T, Eriksson K, Eriksson JG, Lyssenko V, Groop L.

Diabetologia. 2012 Jan;55(1):94-104. doi: 10.1007/s00125-011-2300-8. Epub 2011 Sep 16.

PMID:
21922321
[PubMed - indexed for MEDLINE]
10.

Paired-homeodomain transcription factor PAX4 acts as a transcriptional repressor in early pancreatic development.

Smith SB, Ee HC, Conners JR, German MS.

Mol Cell Biol. 1999 Dec;19(12):8272-80.

PMID:
10567552
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

CCCTC-binding factor mediates effects of glucose on beta cell survival.

Tsui S, Dai W, Lu L.

Cell Prolif. 2014 Feb;47(1):28-37. doi: 10.1111/cpr.12085. Epub 2013 Dec 20.

PMID:
24354619
[PubMed - indexed for MEDLINE]
12.

The activation of the rat insulin gene II by BETA2 and PDX-1 in rat insulinoma cells is repressed by Pax6.

Wolf G, Hessabi B, Karkour A, Henrion U, Dahlhaus M, Ostmann A, Giese B, Fraunholz M, Grabarczyk P, Jack R, Walther R.

Mol Endocrinol. 2010 Dec;24(12):2331-42. doi: 10.1210/me.2009-0220. Epub 2010 Oct 13.

PMID:
20943817
[PubMed - indexed for MEDLINE]
13.

MafB: an activator of the glucagon gene expressed in developing islet alpha- and beta-cells.

Artner I, Le Lay J, Hang Y, Elghazi L, Schisler JC, Henderson E, Sosa-Pineda B, Stein R.

Diabetes. 2006 Feb;55(2):297-304.

PMID:
16443760
[PubMed - indexed for MEDLINE]
Free Article
14.

Glial cell line-derived neurotrophic factor enhances neurogenin3 gene expression and beta-cell proliferation in the developing mouse pancreas.

Mwangi SM, Usta Y, Raja SM, Anitha M, Chandrasekharan B, Parsadanian A, Sitaraman SV, Srinivasan S.

Am J Physiol Gastrointest Liver Physiol. 2010 Jul;299(1):G283-92. doi: 10.1152/ajpgi.00096.2010. Epub 2010 May 6.

PMID:
20448145
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Retinal pigmented epithelium determination requires the redundant activities of Pax2 and Pax6.

Bäumer N, Marquardt T, Stoykova A, Spieler D, Treichel D, Ashery-Padan R, Gruss P.

Development. 2003 Jul;130(13):2903-15.

PMID:
12756174
[PubMed - indexed for MEDLINE]
Free Article
16.

Mutant PAX6 downregulates prohormone convertase 2 expression in mouse islets.

Chen Y, Cao W, Zhou S, Shen L, Wen J.

Exp Biol Med (Maywood). 2013 Nov 1;238(11):1259-64. doi: 10.1177/1535370213502627. Epub 2013 Sep 18.

PMID:
24047795
[PubMed - indexed for MEDLINE]
17.

The diabetes-linked transcription factor Pax4 is expressed in human pancreatic islets and is activated by mitogens and GLP-1.

Brun T, Hu He KH, Lupi R, Boehm B, Wojtusciszyn A, Sauter N, Donath M, Marchetti P, Maedler K, Gauthier BR.

Hum Mol Genet. 2008 Feb 15;17(4):478-89. Epub 2007 Nov 7.

PMID:
17989064
[PubMed - indexed for MEDLINE]
Free Article
18.

CTCF mediates effect of insulin on glucagon expression.

Tsui S, Gao J, Wang C, Lu L.

Exp Cell Res. 2012 May 1;318(8):887-95. doi: 10.1016/j.yexcr.2012.03.001. Epub 2012 Mar 8.

PMID:
22426149
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Pax4 represses pancreatic glucagon gene expression.

Petersen HV, Jørgensen MC, Andersen FG, Jensen J, F-Nielsen T, Jørgensen R, Madsen OD, Serup P.

Mol Cell Biol Res Commun. 2000 Apr;3(4):249-54.

PMID:
10891400
[PubMed - indexed for MEDLINE]
20.

In vivo conditional Pax4 overexpression in mature islet β-cells prevents stress-induced hyperglycemia in mice.

Hu He KH, Lorenzo PI, Brun T, Jimenez Moreno CM, Aeberhard D, Vallejo Ortega J, Cornu M, Thorel F, Gjinovci A, Thorens B, Herrera PL, Meda P, Wollheim CB, Gauthier BR.

Diabetes. 2011 Jun;60(6):1705-15. doi: 10.2337/db10-1102. Epub 2011 Apr 26.

PMID:
21521872
[PubMed - indexed for MEDLINE]
Free PMC Article

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