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Results: 1 to 20 of 250

1.

Synthesis of antitumor azolato-bridged dinuclear platinum(ii) complexes with in vivo antitumor efficacy and unique in vitro cytotoxicity profiles.

Komeda S, Takayama H, Suzuki T, Odani A, Yamori T, Chikuma M.

Metallomics. 2013 May;5(5):461-8. doi: 10.1039/c3mt00040k. Epub 2013 Apr 23.

PMID:
23608770
[PubMed - indexed for MEDLINE]
2.
3.

[Drug discovery research in in-vivo antitumor-active azolato-bridged dinuclear Pt(II) complexes].

Komeda S.

Yakugaku Zasshi. 2012;132(3):253-9. Review. Japanese.

PMID:
22382827
[PubMed - indexed for MEDLINE]
Free Article
4.

A novel isomerization on interaction of antitumor-active azole-bridged dinuclear platinum(II) complexes with 9-ethylguanine. Platinum(II) atom migration from N2 to N3 on 1,2,3-triazole.

Komeda S, Lutz M, Spek AL, Yamanaka Y, Sato T, Chikuma M, Reedijk J.

J Am Chem Soc. 2002 May 1;124(17):4738-46.

PMID:
11971723
[PubMed - indexed for MEDLINE]
5.

Novel oximato-bridged platinum(II) di- and trimer(s): synthetic, structural, and in vitro anticancer activity studies.

Scaffidi-Domianello YY, Legin AA, Jakupec MA, Roller A, Kukushkin VY, Galanski M, Keppler BK.

Inorg Chem. 2012 Jul 2;51(13):7153-63. doi: 10.1021/ic300148e. Epub 2012 Jun 12.

PMID:
22691006
[PubMed - indexed for MEDLINE]
6.

Second- and higher-order structural changes of DNA induced by antitumor-active tetrazolato-bridged dinuclear platinum(II) complexes with different types of 5-substituent.

Uemura M, Yoshikawa Y, Yoshikawa K, Sato T, Mino Y, Chikuma M, Komeda S.

J Inorg Biochem. 2013 Oct;127:169-74. doi: 10.1016/j.jinorgbio.2013.05.004. Epub 2013 May 9.

PMID:
23725767
[PubMed - indexed for MEDLINE]
7.

Synthesis, structural characterization, and antitumor properties of a novel class of large-ring platinum(II) chelate complexes incorporating the cis-1,4-diaminocyclohexane ligand in a unique locked boat conformation.

Hoeschele JD, Showalter HD, Kraker AJ, Elliott WL, Roberts BJ, Kampf JW.

J Med Chem. 1994 Aug 19;37(17):2630-6.

PMID:
8064793
[PubMed - indexed for MEDLINE]
8.

Energetics, conformation, and recognition of DNA duplexes containing a major adduct of an anticancer azolato-bridged dinuclear Pt(II) complex.

Mlcouskova J, Malina J, Novohradsky V, Kasparkova J, Komeda S, Brabec V.

Biochim Biophys Acta. 2012 Oct;1820(10):1502-11. doi: 10.1016/j.bbagen.2012.05.014. Epub 2012 Jun 7.

PMID:
22683702
[PubMed - indexed for MEDLINE]
9.

DNA conformation and repair of polymeric natural DNA damaged by antitumor azolato-bridged dinuclear Pt(II) complex.

Mlcouskova J, Kasparkova J, Suchankova T, Komeda S, Brabec V.

J Inorg Biochem. 2012 Sep;114:15-23. doi: 10.1016/j.jinorgbio.2012.04.015. Epub 2012 May 4.

PMID:
22687561
[PubMed - indexed for MEDLINE]
10.

New antitumor-active azole-bridged dinuclear platinum(II) complexes: synthesis, characterization, crystal structures, and cytotoxic studies.

Komeda S, Lutz M, Spek AL, Chikuma M, Reedijk J.

Inorg Chem. 2000 Sep 18;39(19):4230-6. Erratum in: Inorg Chem 2000 Sep 18;39(19):4382.

PMID:
11196916
[PubMed - indexed for MEDLINE]
11.

Highly efficient DNA compaction mediated by an in vivo antitumor-active tetrazolato-bridged dinuclear platinum(II) complex.

Yoshikawa Y, Komeda S, Uemura M, Kanbe T, Chikuma M, Yoshikawa K, Imanaka T.

Inorg Chem. 2011 Nov 21;50(22):11729-35. doi: 10.1021/ic2017165. Epub 2011 Oct 17.

PMID:
22004345
[PubMed - indexed for MEDLINE]
12.

Synthesis and in vitro and in vivo antitumor activity of a series of trans platinum antitumor complexes.

Kelland LR, Barnard CF, Evans IG, Murrer BA, Theobald BR, Wyer SB, Goddard PM, Jones M, Valenti M, Bryant A, et al.

J Med Chem. 1995 Aug 4;38(16):3016-24.

PMID:
7636864
[PubMed - indexed for MEDLINE]
13.

Synthesis, characterization, and biological evaluation of new tetrazole-based platinum(II) and palladium(II) chlorido complexes--potent cisplatin analogues and their trans isomers.

Serebryanskaya TV, Yung T, Bogdanov AA, Shchebet A, Johnsen SA, Lyakhov AS, Ivashkevich LS, Ibrahimava ZA, Garbuzenco TS, Kolesnikova TS, Melnova NI, Gaponik PN, Ivashkevich OA.

J Inorg Biochem. 2013 Mar;120:44-53. doi: 10.1016/j.jinorgbio.2012.12.001. Epub 2012 Dec 13.

PMID:
23305964
[PubMed - indexed for MEDLINE]
14.

Anticancer activity in murine and human tumor cell lines of bis(platinum) complexes incorporating straight-chain aliphatic diamine linker groups.

Kraker AJ, Hoeschele JD, Elliott WL, Showalter HD, Sercel AD, Farrell NP.

J Med Chem. 1992 Nov 27;35(24):4526-32.

PMID:
1335074
[PubMed - indexed for MEDLINE]
15.

New isomeric azine-bridged dinuclear platinum(II) complexes circumvent cross-resistance to cisplatin.

Komeda S, Kalayda GV, Lutz M, Spek AL, Yamanaka Y, Sato T, Chikuma M, Reedijk J.

J Med Chem. 2003 Mar 27;46(7):1210-9.

PMID:
12646031
[PubMed - indexed for MEDLINE]
17.

Synthesis, characterization and antitumor activity of novel octahedral Pt(IV) complexes.

Kwon YE, Whang KJ, Park YJ, Kim KH.

Bioorg Med Chem. 2003 Apr 17;11(8):1669-76.

PMID:
12659753
[PubMed - indexed for MEDLINE]
18.

Synthesis and biological activity of binuclear platinum complexes containing two monofunctional cis-[Pt(NH3)2Cl]+ units bridged by 4,4'-dipyridyl selenides or sulfides.

Zhao G, Lin H, Zhu S, Sun H, Chen Y.

Anticancer Drug Des. 1998 Oct;13(7):769-77.

PMID:
9807161
[PubMed - indexed for MEDLINE]
19.

Preparation of antitumor oxaliplatin/cisplatin docking dinuclear platinum complex.

Noji M, Kizu R, Takeda Y, Akiyama N, Yoshizaki I, Eriguchi M, Kidani Y.

Biomed Pharmacother. 2005 Jun;59(5):224-9.

PMID:
15919175
[PubMed - indexed for MEDLINE]
20.

Inversion of the cis geometry requirement for cytotoxicity in structurally novel platinum(II) complexes containing the bidentate N,O-donor pyridin-2-yl-acetate.

Bierbach U, Sabat M, Farrell N.

Inorg Chem. 2000 May 1;39(9):1882-90. Erratum in: Inorg Chem 2000 Jun 26;39(13):2960.

PMID:
11428108
[PubMed - indexed for MEDLINE]
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