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Items: 1 to 20 of 87

1.

Discovery of a new bioactive molecule for neuroblastoma.

Leitão A, Schramm A, Eggert A.

Chem Biol Drug Des. 2013 Aug;82(2):233-41. doi: 10.1111/cbdd.12148. Epub 2013 Jul 1.

PMID:
23601248
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Signal transduction pathways through TRK-A and TRK-B receptors in human neuroblastoma cells.

Sugimoto T, Kuroda H, Horii Y, Moritake H, Tanaka T, Hattori S.

Jpn J Cancer Res. 2001 Feb;92(2):152-60.

PMID:
11223544
4.

UCN-01 alters phosphorylation of Akt and GSK3beta and induces apoptosis in six independent human neuroblastoma cell lines.

Shankar SL, Krupski M, Parashar B, Okwuaka C, O'Guin K, Mani S, Shafit-Zagardo B.

J Neurochem. 2004 Aug;90(3):702-11.

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Prognostic and biological role of neurotrophin-receptor TrkA and TrkB in neuroblastoma.

Eggert A, Ikegaki N, Liu XG, Brodeur GM.

Klin Padiatr. 2000 Jul-Aug;212(4):200-5.

PMID:
10994551
8.

Identification of novel candidate compounds targeting TrkB to induce apoptosis in neuroblastoma.

Nakamura Y, Suganami A, Fukuda M, Hasan MK, Yokochi T, Takatori A, Satoh S, Hoshino T, Tamura Y, Nakagawara A.

Cancer Med. 2014 Feb;3(1):25-35. doi: 10.1002/cam4.175. Epub 2014 Jan 1.

9.

MYC inhibition induces metabolic changes leading to accumulation of lipid droplets in tumor cells.

Zirath H, Frenzel A, Oliynyk G, Segerström L, Westermark UK, Larsson K, Munksgaard Persson M, Hultenby K, Lehtiö J, Einvik C, Påhlman S, Kogner P, Jakobsson PJ, Henriksson MA.

Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):10258-63. doi: 10.1073/pnas.1222404110. Epub 2013 Jun 3.

10.

Biological characterization of AT7519, a small-molecule inhibitor of cyclin-dependent kinases, in human tumor cell lines.

Squires MS, Feltell RE, Wallis NG, Lewis EJ, Smith DM, Cross DM, Lyons JF, Thompson NT.

Mol Cancer Ther. 2009 Feb;8(2):324-32. doi: 10.1158/1535-7163.MCT-08-0890. Epub 2009 Jan 27.

11.

Down-regulation of insulin-like growth factor I receptor activity by NVP-AEW541 has an antitumor effect on neuroblastoma cells in vitro and in vivo.

Tanno B, Mancini C, Vitali R, Mancuso M, McDowell HP, Dominici C, Raschellà G.

Clin Cancer Res. 2006 Nov 15;12(22):6772-80.

12.

Microarray analysis reveals differential gene expression patterns and regulation of single target genes contributing to the opposing phenotype of TrkA- and TrkB-expressing neuroblastomas.

Schulte JH, Schramm A, Klein-Hitpass L, Klenk M, Wessels H, Hauffa BP, Eils J, Eils R, Brodeur GM, Schweigerer L, Havers W, Eggert A.

Oncogene. 2005 Jan 6;24(1):165-77.

PMID:
15637590
13.

Identification and preclinical characterization of AZ-23, a novel, selective, and orally bioavailable inhibitor of the Trk kinase pathway.

Thress K, Macintyre T, Wang H, Whitston D, Liu ZY, Hoffmann E, Wang T, Brown JL, Webster K, Omer C, Zage PE, Zeng L, Zweidler-McKay PA.

Mol Cancer Ther. 2009 Jul;8(7):1818-27. doi: 10.1158/1535-7163.MCT-09-0036. Epub 2009 Jun 9.

14.

Integrating virtual screening and combinatorial chemistry for accelerated drug discovery.

López-Vallejo F, Caulfield T, Martínez-Mayorga K, Giulianotti MA, Nefzi A, Houghten RA, Medina-Franco JL.

Comb Chem High Throughput Screen. 2011 Jul;14(6):475-87. Review.

PMID:
21521151
15.

Molecular dissection of TrkA signal transduction pathways mediating differentiation in human neuroblastoma cells.

Eggert A, Ikegaki N, Liu X, Chou TT, Lee VM, Trojanowski JQ, Brodeur GM.

Oncogene. 2000 Apr 13;19(16):2043-51.

16.

Library construction and biological evaluation of enmein-type diterpenoid analogues as potential anticancer agents.

Li D, Xu S, Cai H, Pei L, Wang L, Wu X, Yao H, Jiang J, Sun Y, Xu J.

ChemMedChem. 2013 May;8(5):812-8. doi: 10.1002/cmdc.201200559. Epub 2013 Mar 20.

PMID:
23520191
17.

Effect of imatinib mesylate on neuroblastoma tumorigenesis and vascular endothelial growth factor expression.

Beppu K, Jaboine J, Merchant MS, Mackall CL, Thiele CJ.

J Natl Cancer Inst. 2004 Jan 7;96(1):46-55.

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Applying ligands profiling using multiple extended electron distribution based field templates and feature trees similarity searching in the discovery of new generation of urea-based antineoplastic kinase inhibitors.

Dokla EM, Mahmoud AH, Elsayed MS, El-Khatib AH, Linscheid MW, Abouzid KA.

PLoS One. 2012;7(11):e49284. doi: 10.1371/journal.pone.0049284. Epub 2012 Nov 20.

20.

Novel functional interactions between Trk kinase and p75 neurotrophin receptor in neuroblastoma cells.

Lachyankar MB, Condon PJ, Daou MC, De AK, Levine JB, Obermeier A, Ross AH.

J Neurosci Res. 2003 Jan 15;71(2):157-72.

PMID:
12503079
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