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Items: 1 to 20 of 93

1.

Systematic evaluation of candidate ligands regulating ectodomain shedding of amyloid precursor protein.

Rice HC, Young-Pearse TL, Selkoe DJ.

Biochemistry. 2013 May 14;52(19):3264-77. doi: 10.1021/bi400165f. Epub 2013 May 2.

2.

Interaction of reelin with amyloid precursor protein promotes neurite outgrowth.

Hoe HS, Lee KJ, Carney RS, Lee J, Markova A, Lee JY, Howell BW, Hyman BT, Pak DT, Bu G, Rebeck GW.

J Neurosci. 2009 Jun 10;29(23):7459-73. doi: 10.1523/JNEUROSCI.4872-08.2009.

3.

Reduced Reelin expression accelerates amyloid-beta plaque formation and tau pathology in transgenic Alzheimer's disease mice.

Kocherhans S, Madhusudan A, Doehner J, Breu KS, Nitsch RM, Fritschy JM, Knuesel I.

J Neurosci. 2010 Jul 7;30(27):9228-40. doi: 10.1523/JNEUROSCI.0418-10.2010.

4.

DAB1 and Reelin effects on amyloid precursor protein and ApoE receptor 2 trafficking and processing.

Hoe HS, Tran TS, Matsuoka Y, Howell BW, Rebeck GW.

J Biol Chem. 2006 Nov 17;281(46):35176-85. Epub 2006 Sep 1.

5.

Reelin delays amyloid-beta fibril formation and rescues cognitive deficits in a model of Alzheimer's disease.

Pujadas L, Rossi D, Andrés R, Teixeira CM, Serra-Vidal B, Parcerisas A, Maldonado R, Giralt E, Carulla N, Soriano E.

Nat Commun. 2014 Mar 6;5:3443. doi: 10.1038/ncomms4443.

PMID:
24599114
6.

Beta-amyloid controls altered Reelin expression and processing in Alzheimer's disease.

Botella-López A, Cuchillo-Ibáñez I, Cotrufo T, Mok SS, Li QX, Barquero MS, Dierssen M, Soriano E, Sáez-Valero J.

Neurobiol Dis. 2010 Mar;37(3):682-91. doi: 10.1016/j.nbd.2009.12.006. Epub 2009 Dec 16.

PMID:
20025970
7.

Reelin-immunoreactivity in the hippocampal formation of 9-month-old wildtype mouse: effects of APP/PS1 genotype and ovariectomy.

Miettinen R, Riedel A, Kalesnykas G, Kettunen HP, Puoliväli J, Soininen H, Arendt T.

J Chem Neuroanat. 2005 Oct;30(2-3):105-18.

PMID:
16081247
8.

Reelin depletion in the entorhinal cortex of human amyloid precursor protein transgenic mice and humans with Alzheimer's disease.

Chin J, Massaro CM, Palop JJ, Thwin MT, Yu GQ, Bien-Ly N, Bender A, Mucke L.

J Neurosci. 2007 Mar 14;27(11):2727-33.

9.

Atorvastatin-induced activation of Alzheimer's alpha secretase is resistant to standard inhibitors of protein phosphorylation-regulated ectodomain shedding.

Parvathy S, Ehrlich M, Pedrini S, Diaz N, Refolo L, Buxbaum JD, Bogush A, Petanceska S, Gandy S.

J Neurochem. 2004 Aug;90(4):1005-10.

10.

Co-localization of Reelin and proteolytic AbetaPP fragments in hippocampal plaques in aged wild-type mice.

Doehner J, Madhusudan A, Konietzko U, Fritschy JM, Knuesel I.

J Alzheimers Dis. 2010;19(4):1339-57. doi: 10.3233/JAD-2010-1333.

PMID:
20061602
11.

Determination of the proteolytic cleavage sites of the amyloid precursor-like protein 2 by the proteases ADAM10, BACE1 and γ-secretase.

Hogl S, Kuhn PH, Colombo A, Lichtenthaler SF.

PLoS One. 2011;6(6):e21337. doi: 10.1371/journal.pone.0021337. Epub 2011 Jun 17.

12.

Reelin in plaques of beta-amyloid precursor protein and presenilin-1 double-transgenic mice.

Wirths O, Multhaup G, Czech C, Blanchard V, Tremp G, Pradier L, Beyreuther K, Bayer TA.

Neurosci Lett. 2001 Dec 28;316(3):145-8.

PMID:
11744223
13.

Phosphorylation of FE65 Ser610 by serum- and glucocorticoid-induced kinase 1 modulates Alzheimer's disease amyloid precursor protein processing.

Chow WN, Ngo JC, Li W, Chen YW, Tam KM, Chan HY, Miller CC, Lau KF.

Biochem J. 2015 Sep 15;470(3):303-17. doi: 10.1042/BJ20141485. Epub 2015 Jul 17.

14.

LRRTM3 promotes processing of amyloid-precursor protein by BACE1 and is a positional candidate gene for late-onset Alzheimer's disease.

Majercak J, Ray WJ, Espeseth A, Simon A, Shi XP, Wolffe C, Getty K, Marine S, Stec E, Ferrer M, Strulovici B, Bartz S, Gates A, Xu M, Huang Q, Ma L, Shughrue P, Burchard J, Colussi D, Pietrak B, Kahana J, Beher D, Rosahl T, Shearman M, Hazuda D, Sachs AB, Koblan KS, Seabrook GR, Stone DJ.

Proc Natl Acad Sci U S A. 2006 Nov 21;103(47):17967-72. Epub 2006 Nov 10.

15.

The gamma-secretase-generated intracellular domain of beta-amyloid precursor protein binds Numb and inhibits Notch signaling.

Roncarati R, Sestan N, Scheinfeld MH, Berechid BE, Lopez PA, Meucci O, McGlade JC, Rakic P, D'Adamio L.

Proc Natl Acad Sci U S A. 2002 May 14;99(10):7102-7.

17.

Age-related accumulation of Reelin in amyloid-like deposits.

Knuesel I, Nyffeler M, Mormède C, Muhia M, Meyer U, Pietropaolo S, Yee BK, Pryce CR, LaFerla FM, Marighetto A, Feldon J.

Neurobiol Aging. 2009 May;30(5):697-716. Epub 2007 Sep 27.

PMID:
17904250
18.

Insulin-like growth factor-1 (IGF-1)-induced processing of amyloid-beta precursor protein (APP) and APP-like protein 2 is mediated by different metalloproteinases.

Jacobsen KT, Adlerz L, Multhaup G, Iverfeldt K.

J Biol Chem. 2010 Apr 2;285(14):10223-31. doi: 10.1074/jbc.M109.038224. Epub 2010 Feb 5.

19.

IGF-1-induced processing of the amyloid precursor protein family is mediated by different signaling pathways.

Adlerz L, Holback S, Multhaup G, Iverfeldt K.

J Biol Chem. 2007 Apr 6;282(14):10203-9. Epub 2007 Feb 14.

20.
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