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Polyelectrolyte multilayers promote stent-mediated delivery of DNA to vascular tissue.

Saurer EM, Jewell CM, Roenneburg DA, Bechler SL, Torrealba JR, Hacker TA, Lynn DM.

Biomacromolecules. 2013 May 13;14(5):1696-704. doi: 10.1021/bm4005222. Epub 2013 May 2.


Reduction of intimal hyperplasia in injured rat arteries promoted by catheter balloons coated with polyelectrolyte multilayers that contain plasmid DNA encoding PKCδ.

Bechler SL, Si Y, Yu Y, Ren J, Liu B, Lynn DM.

Biomaterials. 2013 Jan;34(1):226-36. doi: 10.1016/j.biomaterials.2012.09.010. Epub 2012 Oct 13.


Delivery of plasmid DNA to vascular tissue in vivo using catheter balloons coated with polyelectrolyte multilayers.

Saurer EM, Yamanouchi D, Liu B, Lynn DM.

Biomaterials. 2011 Jan;32(2):610-8. doi: 10.1016/j.biomaterials.2010.09.009. Epub 2010 Oct 8.


Release of plasmid DNA from intravascular stents coated with ultrathin multilayered polyelectrolyte films.

Jewell CM, Zhang J, Fredin NJ, Wolff MR, Hacker TA, Lynn DM.

Biomacromolecules. 2006 Sep;7(9):2483-91.


Degradable polyelectrolyte multilayers that promote the release of siRNA.

Flessner RM, Jewell CM, Anderson DG, Lynn DM.

Langmuir. 2011 Jun 21;27(12):7868-76. doi: 10.1021/la200815t. Epub 2011 May 16.


Rapid release of plasmid DNA from surfaces coated with polyelectrolyte multilayers promoted by the application of electrochemical potentials.

Aytar BS, Prausnitz MR, Lynn DM.

ACS Appl Mater Interfaces. 2012 May;4(5):2726-34. doi: 10.1021/am3003632. Epub 2012 May 3.


Assembly of erodible, DNA-containing thin films on the surfaces of polymer microparticles: toward a layer-by-layer approach to the delivery of DNA to antigen-presenting cells.

Saurer EM, Jewell CM, Kuchenreuther JM, Lynn DM.

Acta Biomater. 2009 Mar;5(3):913-24. doi: 10.1016/j.actbio.2008.08.022. Epub 2008 Sep 11.


Release of DNA from polyelectrolyte multilayers fabricated using 'charge-shifting' cationic polymers: tunable temporal control and sequential, multi-agent release.

Sun B, Lynn DM.

J Control Release. 2010 Nov 20;148(1):91-100. doi: 10.1016/j.jconrel.2010.07.112. Epub 2010 Jul 30.


Layer-by-layer assembly of DNA- and protein-containing films on microneedles for drug delivery to the skin.

Saurer EM, Flessner RM, Sullivan SP, Prausnitz MR, Lynn DM.

Biomacromolecules. 2010 Nov 8;11(11):3136-43. doi: 10.1021/bm1009443. Epub 2010 Oct 13.


Transgene delivery of plasmid DNA to smooth muscle cells and macrophages from a biostable polymer-coated stent.

Takahashi A, Palmer-Opolski M, Smith RC, Walsh K.

Gene Ther. 2003 Aug;10(17):1471-8.


Multilayered polyelectrolyte films promote the direct and localized delivery of DNA to cells.

Jewell CM, Zhang J, Fredin NJ, Lynn DM.

J Control Release. 2005 Aug 18;106(1-2):214-23.


Local gene transfer of phVEGF-2 plasmid by gene-eluting stents: an alternative strategy for inhibition of restenosis.

Walter DH, Cejna M, Diaz-Sandoval L, Willis S, Kirkwood L, Stratford PW, Tietz AB, Kirchmair R, Silver M, Curry C, Wecker A, Yoon YS, Heidenreich R, Hanley A, Kearney M, Tio FO, Kuenzler P, Isner JM, Losordo DW.

Circulation. 2004 Jul 6;110(1):36-45. Epub 2004 Jun 21.


Development of a functionalized polymer for stent coating in the arterial delivery of small interfering RNA.

San Juan A, Bala M, Hlawaty H, Portes P, Vranckx R, Feldman LJ, Letourneur D.

Biomacromolecules. 2009 Nov 9;10(11):3074-80. doi: 10.1021/bm900740g.


[A novel anti-DNA antibody modified coronary stent for site-specific plasmid DNA delivery].

Jin X, Leng XG, Liu LX, Gu HG, Zhang C, Wang H, Song CX.

Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2006 Oct;28(5):665-9. Chinese.


Gene delivery in vitro and in vivo from bioreducible multilayered polyelectrolyte films of plasmid DNA.

Blacklock J, You YZ, Zhou QH, Mao G, Oupický D.

Biomaterials. 2009 Feb;30(5):939-50. doi: 10.1016/j.biomaterials.2008.10.012. Epub 2008 Nov 17.


Polymer Multilayers that Promote the Rapid Release and Contact Transfer of DNA.

Yu Y, Si Y, Bechler SL, Liu B, Lynn DM.

Biomacromolecules. 2015 Sep 14;16(9):2998-3007. doi: 10.1021/acs.biomac.5b00905. Epub 2015 Aug 28.

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