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Items: 1 to 20 of 100

1.

Tumor suppressor p53 plays a key role in induction of both tristetraprolin and let-7 in human cancer cells.

Lee JY, Kim HJ, Yoon NA, Lee WH, Min YJ, Ko BK, Lee BJ, Lee A, Cha HJ, Cho WJ, Park JW.

Nucleic Acids Res. 2013 Jun;41(11):5614-25. doi: 10.1093/nar/gkt222. Epub 2013 Apr 16.

2.

Ectopic over-expression of tristetraprolin in human cancer cells promotes biogenesis of let-7 by down-regulation of Lin28.

Kim CW, Vo MT, Kim HK, Lee HH, Yoon NA, Lee BJ, Min YJ, Joo WD, Cha HJ, Park JW, Cho WJ.

Nucleic Acids Res. 2012 May;40(9):3856-69. doi: 10.1093/nar/gkr1302. Epub 2011 Dec 30.

3.

The mRNA binding proteins HuR and tristetraprolin regulate cyclooxygenase 2 expression during colon carcinogenesis.

Young LE, Sanduja S, Bemis-Standoli K, Pena EA, Price RL, Dixon DA.

Gastroenterology. 2009 May;136(5):1669-79. doi: 10.1053/j.gastro.2009.01.010. Epub 2009 Jan 15.

4.

A synonymous polymorphism of the Tristetraprolin (TTP) gene, an AU-rich mRNA-binding protein, affects translation efficiency and response to Herceptin treatment in breast cancer patients.

Griseri P, Bourcier C, Hieblot C, Essafi-Benkhadir K, Chamorey E, Touriol C, Pagès G.

Hum Mol Genet. 2011 Dec 1;20(23):4556-68. doi: 10.1093/hmg/ddr390. Epub 2011 Aug 29.

5.

Tristetraprolin down-regulates IL-23 expression in colon cancer cells.

Lee HH, Yang SS, Vo MT, Cho WJ, Lee BJ, Leem SH, Lee SH, Cha HJ, Park JW.

Mol Cells. 2013 Dec;36(6):571-6. doi: 10.1007/s10059-013-0268-6. Epub 2013 Nov 29.

6.

Tristetraprolin regulates expression of VEGF and tumorigenesis in human colon cancer.

Lee HH, Son YJ, Lee WH, Park YW, Chae SW, Cho WJ, Kim YM, Choi HJ, Choi DH, Jung SW, Min YJ, Park SE, Lee BJ, Cha HJ, Park JW.

Int J Cancer. 2010 Apr 15;126(8):1817-27. doi: 10.1002/ijc.24847.

7.

CREB targets define the gene expression signature of malignancies having reduced levels of the tumor suppressor tristetraprolin.

Fallahi M, Amelio AL, Cleveland JL, Rounbehler RJ.

PLoS One. 2014 Dec 26;9(12):e115517. doi: 10.1371/journal.pone.0115517. eCollection 2014.

8.

Constitutive ERK activity induces downregulation of tristetraprolin, a major protein controlling interleukin8/CXCL8 mRNA stability in melanoma cells.

Bourcier C, Griseri P, Grépin R, Bertolotto C, Mazure N, Pagès G.

Am J Physiol Cell Physiol. 2011 Sep;301(3):C609-18. doi: 10.1152/ajpcell.00506.2010. Epub 2011 May 18.

9.

Functional switching of TGF-beta1 signaling in liver cancer via epigenetic modulation of a single CpG site in TTP promoter.

Sohn BH, Park IY, Lee JJ, Yang SJ, Jang YJ, Park KC, Kim DJ, Lee DC, Sohn HA, Kim TW, Yoo HS, Choi JY, Bae YS, Yeom YI.

Gastroenterology. 2010 May;138(5):1898-908. doi: 10.1053/j.gastro.2009.12.044. Epub 2009 Dec 29.

PMID:
20038433
10.

Mammary differentiation induces expression of Tristetraprolin, a tumor suppressor AU-rich mRNA-binding protein.

Goddio MV, Gattelli A, Slomiansky V, Lacunza E, Gingerich T, Tocci JM, Facchinetti MM, Curino AC, LaMarre J, Abba MC, Kordon EC.

Breast Cancer Res Treat. 2012 Oct;135(3):749-58. doi: 10.1007/s10549-012-2216-0. Epub 2012 Aug 29.

PMID:
22968621
11.

Stability of the LATS2 tumor suppressor gene is regulated by tristetraprolin.

Lee HH, Vo MT, Kim HJ, Lee UH, Kim CW, Kim HK, Ko MS, Lee WH, Cha SJ, Min YJ, Choi DH, Suh HS, Lee BJ, Park JW, Cho WJ.

J Biol Chem. 2010 Jun 4;285(23):17329-37. doi: 10.1074/jbc.M109.094235. Epub 2010 Mar 24.

12.

Expression of proviral integration site for Moloney murine leukemia virus 1 (Pim-1) is post-transcriptionally regulated by tristetraprolin in cancer cells.

Kim HK, Kim CW, Vo MT, Lee HH, Lee JY, Yoon NA, Lee CY, Moon CH, Min YJ, Park JW, Cho WJ.

J Biol Chem. 2012 Aug 17;287(34):28770-8. doi: 10.1074/jbc.M112.376483. Epub 2012 Jun 14.

13.

Role of the p53/p21 system in the response of human colon carcinoma cells to Doxorubicin.

Ravizza R, Gariboldi MB, Passarelli L, Monti E.

BMC Cancer. 2004 Dec 15;4:92.

14.

Depletion of tristetraprolin in breast cancer cells increases interleukin-16 expression and promotes tumor infiltration with monocytes/macrophages.

Milke L, Schulz K, Weigert A, Sha W, Schmid T, Brüne B.

Carcinogenesis. 2013 Apr;34(4):850-7. doi: 10.1093/carcin/bgs387. Epub 2012 Dec 14.

15.

CD95 is part of a let-7/p53/miR-34 regulatory network.

Hau A, Ceppi P, Peter ME.

PLoS One. 2012;7(11):e49636. doi: 10.1371/journal.pone.0049636. Epub 2012 Nov 14.

16.

Tumour suppressor p53 down-regulates the expression of the human hepatocyte nuclear factor 4alpha (HNF4alpha) gene.

Maeda Y, Hwang-Verslues WW, Wei G, Fukazawa T, Durbin ML, Owen LB, Liu X, Sladek FM.

Biochem J. 2006 Dec 1;400(2):303-13.

17.

A mutant p53/let-7i-axis-regulated gene network drives cell migration, invasion and metastasis.

Subramanian M, Francis P, Bilke S, Li XL, Hara T, Lu X, Jones MF, Walker RL, Zhu Y, Pineda M, Lee C, Varanasi L, Yang Y, Martinez LA, Luo J, Ambs S, Sharma S, Wakefield LM, Meltzer PS, Lal A.

Oncogene. 2015 Feb 26;34(9):1094-104. doi: 10.1038/onc.2014.46. Epub 2014 Mar 24.

18.

Transcriptional regulation of tristetraprolin by transforming growth factor-beta in human T cells.

Ogawa K, Chen F, Kim YJ, Chen Y.

J Biol Chem. 2003 Aug 8;278(32):30373-81. Epub 2003 May 15.

19.

MicroRNA-34 mediates AR-dependent p53-induced apoptosis in prostate cancer.

Rokhlin OW, Scheinker VS, Taghiyev AF, Bumcrot D, Glover RA, Cohen MB.

Cancer Biol Ther. 2008 Aug;7(8):1288-96. Epub 2008 Aug 13.

PMID:
18497571
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