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Items: 1 to 20 of 284


NOD2 promotes renal injury by exacerbating inflammation and podocyte insulin resistance in diabetic nephropathy.

Du P, Fan B, Han H, Zhen J, Shang J, Wang X, Li X, Shi W, Tang W, Bao C, Wang Z, Zhang Y, Zhang B, Wei X, Yi F.

Kidney Int. 2013 Aug;84(2):265-76. doi: 10.1038/ki.2013.113. Epub 2013 Apr 17.


Requirement for TLR2 in the development of albuminuria, inflammation and fibrosis in experimental diabetic nephropathy.

Ma J, Wu H, Zhao CY, Panchapakesan U, Pollock C, Chadban SJ.

Int J Clin Exp Pathol. 2014 Jan 15;7(2):481-95. eCollection 2014.


Histone deacetylase 4 selectively contributes to podocyte injury in diabetic nephropathy.

Wang X, Liu J, Zhen J, Zhang C, Wan Q, Liu G, Wei X, Zhang Y, Wang Z, Han H, Xu H, Bao C, Song Z, Zhang X, Li N, Yi F.

Kidney Int. 2014 Oct;86(4):712-25. doi: 10.1038/ki.2014.111. Epub 2014 Apr 9.


Novel role of NOD2 in mediating Ca2+ signaling: evidence from NOD2-regulated podocyte TRPC6 channels in hyperhomocysteinemia.

Han H, Wang Y, Li X, Wang PA, Wei X, Liang W, Ding G, Yu X, Bao C, Zhang Y, Wang Z, Yi F.

Hypertension. 2013 Sep;62(3):506-11. doi: 10.1161/HYPERTENSIONAHA.113.01638. Epub 2013 Jul 15.


NOD-like and Toll-like receptors or inflammasomes contribute to kidney disease in a canonical and a non-canonical manner.

Anders HJ, Lech M.

Kidney Int. 2013 Aug;84(2):225-8. doi: 10.1038/ki.2013.122.


Overexpression of Mafb in podocytes protects against diabetic nephropathy.

Morito N, Yoh K, Ojima M, Okamura M, Nakamura M, Hamada M, Shimohata H, Moriguchi T, Yamagata K, Takahashi S.

J Am Soc Nephrol. 2014 Nov;25(11):2546-57. doi: 10.1681/ASN.2013090993. Epub 2014 Apr 10.


Deletion of soluble epoxide hydrolase gene improves renal endothelial function and reduces renal inflammation and injury in streptozotocin-induced type 1 diabetes.

Elmarakby AA, Faulkner J, Al-Shabrawey M, Wang MH, Maddipati KR, Imig JD.

Am J Physiol Regul Integr Comp Physiol. 2011 Nov;301(5):R1307-17. doi: 10.1152/ajpregu.00759.2010. Epub 2011 Aug 10.


Schisandra chinensis fruit extract attenuates albuminuria and protects podocyte integrity in a mouse model of streptozotocin-induced diabetic nephropathy.

Zhang M, Liu M, Xiong M, Gong J, Tan X.

J Ethnopharmacol. 2012 May 7;141(1):111-8. doi: 10.1016/j.jep.2012.02.007. Epub 2012 Feb 14.


Mesenchymal stem cells ameliorate podocyte injury and proteinuria in a type 1 diabetic nephropathy rat model.

Wang S, Li Y, Zhao J, Zhang J, Huang Y.

Biol Blood Marrow Transplant. 2013 Apr;19(4):538-46. doi: 10.1016/j.bbmt.2013.01.001. Epub 2013 Jan 4.


Deficiency of cannabinoid receptor of type 2 worsens renal functional and structural abnormalities in streptozotocin-induced diabetic mice.

Barutta F, Grimaldi S, Franco I, Bellini S, Gambino R, Pinach S, Corbelli A, Bruno G, Rastaldi MP, Aveta T, Hirsch E, Di Marzo V, Gruden G.

Kidney Int. 2014 Nov;86(5):979-90. doi: 10.1038/ki.2014.165. Epub 2014 May 14.


Protective role of cannabinoid receptor type 2 in a mouse model of diabetic nephropathy.

Barutta F, Piscitelli F, Pinach S, Bruno G, Gambino R, Rastaldi MP, Salvidio G, Di Marzo V, Cavallo Perin P, Gruden G.

Diabetes. 2011 Sep;60(9):2386-96. doi: 10.2337/db10-1809. Epub 2011 Aug 1.


Selective phosphodiesterase-5 (PDE-5) inhibitor vardenafil ameliorates renal damage in type 1 diabetic rats by restoring cyclic 3',5' guanosine monophosphate (cGMP) level in podocytes.

Fang L, Radovits T, Szabó G, Mózes MM, Rosivall L, Kökény G.

Nephrol Dial Transplant. 2013 Jul;28(7):1751-61. doi: 10.1093/ndt/gfs391. Epub 2012 Nov 29.


The purinergic 2X7 receptor participates in renal inflammation and injury induced by high-fat diet: possible role of NLRP3 inflammasome activation.

Solini A, Menini S, Rossi C, Ricci C, Santini E, Blasetti Fantauzzi C, Iacobini C, Pugliese G.

J Pathol. 2013 Nov;231(3):342-53. doi: 10.1002/path.4237. Epub 2013 Sep 3.


Glomerular cell death and inflammation with high-protein diet and diabetes.

Meek RL, LeBoeuf RC, Saha SA, Alpers CE, Hudkins KL, Cooney SK, Anderberg RJ, Tuttle KR.

Nephrol Dial Transplant. 2013 Jul;28(7):1711-20. doi: 10.1093/ndt/gfs579. Epub 2013 Jan 12.


Effects of linalool on inflammation, matrix accumulation and podocyte loss in kidney of streptozotocin-induced diabetic rats.

Deepa B, Venkatraman Anuradha C.

Toxicol Mech Methods. 2013 May;23(4):223-34. doi: 10.3109/15376516.2012.743638. Epub 2013 Jan 16.


eNOS deficiency predisposes podocytes to injury in diabetes.

Yuen DA, Stead BE, Zhang Y, White KE, Kabir MG, Thai K, Advani SL, Connelly KA, Takano T, Zhu L, Cox AJ, Kelly DJ, Gibson IW, Takahashi T, Harris RC, Advani A.

J Am Soc Nephrol. 2012 Nov;23(11):1810-23. doi: 10.1681/ASN.2011121170. Epub 2012 Sep 20.


Expression of SHP-1 induced by hyperglycemia prevents insulin actions in podocytes.

Drapeau N, Lizotte F, Denhez B, Guay A, Kennedy CR, Geraldes P.

Am J Physiol Endocrinol Metab. 2013 Jun 1;304(11):E1188-98. doi: 10.1152/ajpendo.00560.2012. Epub 2013 Mar 26.


Valsartan slows the progression of diabetic nephropathy in db/db mice via a reduction in podocyte injury, and renal oxidative stress and inflammation.

Zhou G, Cheung AK, Liu X, Huang Y.

Clin Sci (Lond). 2014 May;126(10):707-20. doi: 10.1042/CS20130223.


Rapamycin promotes podocyte autophagy and ameliorates renal injury in diabetic mice.

Xiao T, Guan X, Nie L, Wang S, Sun L, He T, Huang Y, Zhang J, Yang K, Wang J, Zhao J.

Mol Cell Biochem. 2014 Sep;394(1-2):145-54. doi: 10.1007/s11010-014-2090-7. Epub 2014 May 22.


Macrophages directly mediate diabetic renal injury.

You H, Gao T, Cooper TK, Brian Reeves W, Awad AS.

Am J Physiol Renal Physiol. 2013 Dec 15;305(12):F1719-27. doi: 10.1152/ajprenal.00141.2013. Epub 2013 Oct 30.

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