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Items: 1 to 20 of 123

1.

Acute myeloid leukemia: advances in diagnosis and classification.

Hasserjian RP.

Int J Lab Hematol. 2013 Jun;35(3):358-66. doi: 10.1111/ijlh.12081. Review.

PMID:
23590662
2.

Prognostic significance of CEBPA mutations in a large cohort of younger adult patients with acute myeloid leukemia: impact of double CEBPA mutations and the interaction with FLT3 and NPM1 mutations.

Green CL, Koo KK, Hills RK, Burnett AK, Linch DC, Gale RE.

J Clin Oncol. 2010 Jun 1;28(16):2739-47. doi: 10.1200/JCO.2009.26.2501. Epub 2010 May 3.

3.

Mutations in nucleophosmin (NPM1) in acute myeloid leukemia (AML): association with other gene abnormalities and previously established gene expression signatures and their favorable prognostic significance.

Verhaak RG, Goudswaard CS, van Putten W, Bijl MA, Sanders MA, Hugens W, Uitterlinden AG, Erpelinck CA, Delwel R, Löwenberg B, Valk PJ.

Blood. 2005 Dec 1;106(12):3747-54. Epub 2005 Aug 18.

4.

Prognostic significance of, and gene and microRNA expression signatures associated with, CEBPA mutations in cytogenetically normal acute myeloid leukemia with high-risk molecular features: a Cancer and Leukemia Group B Study.

Marcucci G, Maharry K, Radmacher MD, Mrózek K, Vukosavljevic T, Paschka P, Whitman SP, Langer C, Baldus CD, Liu CG, Ruppert AS, Powell BL, Carroll AJ, Caligiuri MA, Kolitz JE, Larson RA, Bloomfield CD.

J Clin Oncol. 2008 Nov 1;26(31):5078-87. doi: 10.1200/JCO.2008.17.5554. Epub 2008 Sep 22. Erratum in: J Clin Oncol. 2008 Dec 20;26(36):6021.

5.

Acute Myeloid Leukemia Genetics: Risk Stratification and Implications for Therapy.

Wang ML, Bailey NG.

Arch Pathol Lab Med. 2015 Oct;139(10):1215-23. doi: 10.5858/arpa.2015-0203-RA. Review.

PMID:
26414465
6.

Mutations and treatment outcome in cytogenetically normal acute myeloid leukemia.

Schlenk RF, Döhner K, Krauter J, Fröhling S, Corbacioglu A, Bullinger L, Habdank M, Späth D, Morgan M, Benner A, Schlegelberger B, Heil G, Ganser A, Döhner H; German-Austrian Acute Myeloid Leukemia Study Group.

N Engl J Med. 2008 May 1;358(18):1909-18. doi: 10.1056/NEJMoa074306.

7.

Favorable prognostic impact of NPM1 mutations in older patients with cytogenetically normal de novo acute myeloid leukemia and associated gene- and microRNA-expression signatures: a Cancer and Leukemia Group B study.

Becker H, Marcucci G, Maharry K, Radmacher MD, Mrózek K, Margeson D, Whitman SP, Wu YZ, Schwind S, Paschka P, Powell BL, Carter TH, Kolitz JE, Wetzler M, Carroll AJ, Baer MR, Caligiuri MA, Larson RA, Bloomfield CD.

J Clin Oncol. 2010 Feb 1;28(4):596-604. doi: 10.1200/JCO.2009.25.1496. Epub 2009 Dec 21.

8.

Multiplex high-throughput gene mutation analysis in acute myeloid leukemia.

Dunlap J, Beadling C, Warrick A, Neff T, Fleming WH, Loriaux M, Heinrich MC, Kovacsovics T, Kelemen K, Leeborg N, Gatter K, Braziel RM, Press R, Corless CL, Fan G.

Hum Pathol. 2012 Dec;43(12):2167-76. doi: 10.1016/j.humpath.2012.03.002. Epub 2012 Jun 1.

PMID:
22658276
9.

[Correlation of adult AML Npm1 mutations with prognosis and its relationship with gene mutation of FLT3 and CEBPA].

Bao LY, Wang JS.

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2010 Feb;18(1):19-24. Chinese.

PMID:
20137111
10.

Acute myeloid leukemia with biallelic CEBPA gene mutations and normal karyotype represents a distinct genetic entity associated with a favorable clinical outcome.

Dufour A, Schneider F, Metzeler KH, Hoster E, Schneider S, Zellmeier E, Benthaus T, Sauerland MC, Berdel WE, Büchner T, Wörmann B, Braess J, Hiddemann W, Bohlander SK, Spiekermann K.

J Clin Oncol. 2010 Feb 1;28(4):570-7. doi: 10.1200/JCO.2008.21.6010. Epub 2009 Dec 28.

11.

Acute myeloid leukemia with mutated NPM1: diagnosis, prognosis and therapeutic perspectives.

Falini B, Sportoletti P, Martelli MP.

Curr Opin Oncol. 2009 Nov;21(6):573-81. doi: 10.1097/CCO.0b013e3283313dfa. Review.

PMID:
19770764
12.

Risk assessment in patients with acute myeloid leukemia and a normal karyotype.

Bienz M, Ludwig M, Leibundgut EO, Mueller BU, Ratschiller D, Solenthaler M, Fey MF, Pabst T.

Clin Cancer Res. 2005 Feb 15;11(4):1416-24. Erratum in: Clin Cancer Res. 2005 Aug 1;11(15):5659.

13.

Prognostic factors in AML in relation to (ab)normal karyotype.

Stone RM.

Best Pract Res Clin Haematol. 2009 Dec;22(4):523-8. doi: 10.1016/j.beha.2009.07.003. Review.

PMID:
19959103
14.

FLT3 and NPM1 mutations in myelodysplastic syndromes: Frequency and potential value for predicting progression to acute myeloid leukemia.

Bains A, Luthra R, Medeiros LJ, Zuo Z.

Am J Clin Pathol. 2011 Jan;135(1):62-9. doi: 10.1309/AJCPEI9XU8PYBCIO.

15.

Mutant nucleophosmin (NPM1) predicts favorable prognosis in younger adults with acute myeloid leukemia and normal cytogenetics: interaction with other gene mutations.

Döhner K, Schlenk RF, Habdank M, Scholl C, Rücker FG, Corbacioglu A, Bullinger L, Fröhling S, Döhner H.

Blood. 2005 Dec 1;106(12):3740-6. Epub 2005 Jul 28.

16.

[C-kit, NPM1 and FLT3 gene mutation patterns and their prognostic significance in 656 Chinese patients with acute myeloid leukemia].

Ding ZX, Shen HJ, Miao JC, Chen SN, Qiu QC, Qi XF, Jin ZM, Wu DP, He J.

Zhonghua Xue Ye Xue Za Zhi. 2012 Oct;33(10):829-34. Chinese.

PMID:
23384905
17.

C/EBPA gene mutation and C/EBPA promoter hypermethylation in acute myeloid leukemia with normal cytogenetics.

Lu Y, Chen W, Chen W, Stein A, Weiss LM, Huang Q.

Am J Hematol. 2010 Jun;85(6):426-30. doi: 10.1002/ajh.21706.

18.

NPM1 mutations are more stable than FLT3 mutations during the course of disease in patients with acute myeloid leukemia.

Palmisano M, Grafone T, Ottaviani E, Testoni N, Baccarani M, Martinelli G.

Haematologica. 2007 Sep;92(9):1268-9.

19.

Prognostic implications of gene mutations in acute myeloid leukemia with normal cytogenetics.

Gaidzik V, Döhner K.

Semin Oncol. 2008 Aug;35(4):346-55. doi: 10.1053/j.seminoncol.2008.04.005. Review.

PMID:
18692685
20.

Simultaneous detection of NPM1 and FLT3-ITD mutations by capillary electrophoresis in acute myeloid leukemia.

Noguera NI, Ammatuna E, Zangrilli D, Lavorgna S, Divona M, Buccisano F, Amadori S, Mecucci C, Falini B, Lo-Coco F.

Leukemia. 2005 Aug;19(8):1479-82. Erratum in: Leukemia. 2007 May;21(5):1134.

PMID:
15973451
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