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Adenylyl cyclase 6 deletion increases mortality during sustained β-adrenergic receptor stimulation.

Tang T, Lai NC, Wright AT, Gao MH, Lee P, Guo T, Tang R, McCulloch AD, Hammond HK.

J Mol Cell Cardiol. 2013 Jul;60:60-7. doi: 10.1016/j.yjmcc.2013.04.005. Epub 2013 Apr 12.


Adenylyl cyclase type V deletion increases basal left ventricular function and reduces left ventricular contractile responsiveness to beta-adrenergic stimulation.

Tang T, Lai NC, Roth DM, Drumm J, Guo T, Lee KW, Han PL, Dalton N, Gao MH.

Basic Res Cardiol. 2006 Mar;101(2):117-26. Epub 2005 Nov 11.


Strain-dependent beta-adrenergic receptor function influences myocardial responses to isoproterenol stimulation in mice.

Faulx MD, Ernsberger P, Vatner D, Hoffman RD, Lewis W, Strachan R, Hoit BD.

Am J Physiol Heart Circ Physiol. 2005 Jul;289(1):H30-6. Epub 2005 Mar 4.


Adenylyl cyclase 6 improves calcium uptake and left ventricular function in aged hearts.

Tang T, Hammond HK, Firth A, Yang Y, Gao MH, Yuan JX, Lai NC.

J Am Coll Cardiol. 2011 May 3;57(18):1846-55. doi: 10.1016/j.jacc.2010.11.052.


Overexpression of myocardial Gsalpha prevents full expression of catecholamine desensitization despite increased beta-adrenergic receptor kinase.

Vatner DE, Asai K, Iwase M, Ishikawa Y, Wagner TE, Shannon RP, Homcy CJ, Vatner SF.

J Clin Invest. 1998 May 1;101(9):1916-22.


Adenylyl cyclase type 6 deletion decreases left ventricular function via impaired calcium handling.

Tang T, Gao MH, Lai NC, Firth AL, Takahashi T, Guo T, Yuan JX, Roth DM, Hammond HK.

Circulation. 2008 Jan 1;117(1):61-9. Epub 2007 Dec 10.


Disruption of type 5 adenylyl cyclase prevents β-adrenergic receptor cardiomyopathy: a novel approach to β-adrenergic receptor blockade.

Yan L, Vatner SF, Vatner DE.

Am J Physiol Heart Circ Physiol. 2014 Nov 15;307(10):H1521-8. doi: 10.1152/ajpheart.00491.2014. Epub 2014 Sep 5.


Cardiac-directed adenylyl cyclase expression improves heart function in murine cardiomyopathy.

Roth DM, Gao MH, Lai NC, Drumm J, Dalton N, Zhou JY, Zhu J, Entrikin D, Hammond HK.

Circulation. 1999 Jun 22;99(24):3099-102.


cAMP-mediated beta-adrenergic signaling negatively regulates Gq-coupled receptor-mediated fetal gene response in cardiomyocytes.

Patrizio M, Vago V, Musumeci M, Fecchi K, Sposi NM, Mattei E, Catalano L, Stati T, Marano G.

J Mol Cell Cardiol. 2008 Dec;45(6):761-9. doi: 10.1016/j.yjmcc.2008.09.120. Epub 2008 Sep 25.


Differential alterations in cardiac adrenergic signaling in chronic hypoxia or norepinephrine infusion.

León-Velarde F, Bourin MC, Germack R, Mohammadi K, Crozatier B, Richalet JP.

Am J Physiol Regul Integr Comp Physiol. 2001 Jan;280(1):R274-81.


Impaired beta-adrenergic response and decreased L-type calcium current of hypertrophied left ventricular myocytes in postinfarction heart failure.

Saraiva RM, Chedid NG, Quintero H CC, Díaz G LE, Masuda MO.

Braz J Med Biol Res. 2003 May;36(5):635-48. Epub 2003 Apr 22.


beta-Adrenoceptor density and adenylyl cyclase activity in obese rabbit hearts.

Carroll JF, Kyser CK, Martin MM.

Int J Obes Relat Metab Disord. 2002 May;26(5):627-32.


Sex differences and the effects of ovariectomy on the β-adrenergic contractile response.

McIntosh VJ, Chandrasekera PC, Lasley RD.

Am J Physiol Heart Circ Physiol. 2011 Sep;301(3):H1127-34. doi: 10.1152/ajpheart.00711.2010. Epub 2011 Jun 17.


Comparison of pharmacodynamics between carvedilol and metoprolol in rats with isoproterenol-induced cardiac hypertrophy: effects of carvedilol enantiomers.

Hanada K, Asari K, Saito M, Kawana J, Mita M, Ogata H.

Eur J Pharmacol. 2008 Jul 28;589(1-3):194-200. doi: 10.1016/j.ejphar.2008.04.055. Epub 2008 May 6.


Beta-adrenergic signal transduction and contractility in the canine heart after cardiopulmonary bypass.

Dupuis JY, Li K, Calderone A, Gosselin H, Yang XP, Anand-Srivastava MB, Teijeira J, Rouleau JL.

Cardiovasc Res. 1997 Nov;36(2):223-35.

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